FLUIDIC SYSTEMS AND METHODS FOR ANALYSES
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Accused Products
Abstract
Fluidic systems and methods for analyses are provided. In some embodiments, systems and methods for improved measurement of absorbance/transmission through fluidic systems are described. Specifically, in one set of embodiments, optical elements are fabricated on one side of a transparent fluidic device opposite a series of fluidic channels. The optical elements may guide incident light passing through the device such that most of the light is dispersed away from specific areas of the device, such as intervening portions between the fluidic channels. By decreasing the amount of light incident upon these intervening portions, the amount of noise in the detection signal can be decreased when using certain optical detection systems.
13 Citations
20 Claims
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1. (canceled)
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2. A multiplex assay system comprising:
an article supporting solid-phase assays, said article comprising a rigid planar substrate comprising two or more different liquid containment regions, each liquid containment region comprising at least one analysis region that can be interrogated optically, each analysis region having one or more binding partners associated with a surface of the substrate, wherein said binding partners bind one or more analytes present in a sample in the liquid containment region, and wherein, for at least one liquid containment region, the one or more analytes is selected from the group consisting of prostate specific antigen (PSA), free PSA, complexed-PSA, pro-PSA and human kallikrein protein (hk2). - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
Specification