EXPANDABLE VASCULAR OCCLUSION DEVICE WITH LEAD FRAMING COIL

• US 20160317158A1
• Filed: 05/01/2015
• Published: 11/03/2016
• Est. Priority Date: 05/01/2015
• Status: Active Grant

• Current Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Original Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Inventors: Girnary, Hussein, Slazas, Robert, Lorenzo, Juan
• Granted Patent: US 10,111,670 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2/062 Apparatus for the production of blood vessels made from natural tissue or with layers of living cells prostheses made from natural tissue or living cells A61L27/507
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2230/0069 cylindrical

Abstract

An occlusion device for treating an aneurysm can have an inner embolic device with a proximal section and a distal section. The distal section has a first stiffness and the proximal section has a second stiffness. Further, the device has an expandable mesh capable of a collapsed position and an expanded position. The mesh can be disposed over, and attached to, a portion of the proximal section of the inner embolic device. The first stiffness is greater than the second stiffness and the inner embolic device comprises a preselected shape which assists in transforming the expandable mesh from the collapsed position to the expanded position.

Claims

1. An occlusion device comprising:

an inner embolic element comprising a proximal section and a distal section, wherein the distal section has a first stiffness and the proximal section has a second stiffness; and

an expandable mesh capable of being transformed between a collapsed position and an expanded position, wherein the expandable mesh is disposed over a portion of the proximal section of the inner embolic device.

2. The occlusion device of claim 1 wherein the first stiffness differs from the second stiffness.

3. The occlusion device of claim 1 wherein the inner embolic device comprises a coil having a predetermined preselected shape that assists in transforming the expandable mesh from the collapsed position to the expanded position.

4. The occlusion device of claim 1 wherein the expandable mesh covers substantially the proximal section of the inner embolic element.

5. The occlusion device of claim 1 wherein the expandable mesh comprises a predetermined shape.

6. The occlusion device of claim 5 wherein the expandable mesh takes on the predeterimed shape once in the expanded position.

7. The occlusion device of claim 1 wherein the inner embolic element further comprises a transition zone where the first stiffness changes to the second stiffness.

8. The occlusion device of claim 1 wherein the first stiffness is one of greater than or less than the second stiffness.

9. The occlusion device of claim 1 wherein the first stiffness is at least approximately ten times the second stiffness.

10. The occlusion device of claim 1 wherein the first stiffness is up to approximately twenty times the second stiffness.

11. The occlusion device of claim 1 wherein the first stiffness is up to approximately thirty times the second stiffness.

12. The occlusion device of claim 1 wherein the proximal section of the inner embolic device is in tension and the expandable mesh is in compression when the expandable mesh is in the collapsed position.

13. The occlusion device of claim 1 wherein the distal section comprises a distal length, the proximal section comprises a proximal length, and the distal length is at least 7% of a total length of the inner embolic element.

14. The occlusion device of claim 13, wherein the expandable mesh has a mesh length in the collapsed position, and

wherein the proximal length of the proximal section is approximately 2%-5% longer than the collapsed mesh length.

15. The occlusion device of claim 1, wherein the inner embolic element comprises a coil having a predetermined shape.

16. A method of treating an aneurysm using an occlusion device having an inner embolic element with a proximal section and a distal section, and an expandable mesh, wherein the expandable mesh is disposed over a portion of the proximal section of the inner embolic element and wherein the proximal section having a different stiffness than the distal section, comprising the steps of:

placing the occlusion device within a vessel of a patient;

directing the occlusion device to the aneurysm;

deploying the distal section of the inner embolic element into the aneurysm from a catheter;

assuming, by the distal section of the inner embolic element, a predetermined shape;

deploying the expandable mesh into the aneurysm.

17. The method of claim 16 wherein the distal section of the inner embolic element is a framing coil, and further comprising the step of configuring the different stiffness of inner embolic element so that the framing coil is stiffer than the proximal section.

18. The method of claim 16, wherein the distal section has a stiffness that is at least ten times the stiffness of the proximal section.

19. The method of claim 16, wherein the distal section has a stiffness that is up to twenty times stiffer than the proximal section.

20. The method of claim 16, wherein the distal section has a stiffness that is up to thirty times stiffer than the proximal section.

21. The method of claim 16, wherein the distal section has a length that is approximately at least 7% of a total length of the occlusion device.

22. The method of claim 16, wherein the expandable mesh has a mesh length in a collapsed position;

and

wherein the proximal section has a proximal length, that is approximately 2%-5% longer than the collapsed mesh length.

23. The method of claim 16, wherein the stiffness of the distal section is softer than the proximal part.

24. A method of treating an aneurysm using an occlusion device having an inner embolic element with a proximal section and a distal section, and an expandable mesh, wherein the expandable mesh is disposed over a portion of the distal section of the inner embolic element, and wherein the proximal section having a different stiffness than the distal section, comprising the steps of:

placing the occlusion device within a vessel of a patient;

directing the occlusion device to the aneurysm;

deploying the expandable mesh with the distal section of the inner embolic element into the aneurysm from a catheter;

assuming, by the expandable mesh, a predetermined shape;

deploying the proximal section of the inner embolic element into the aneurysm from a catheter; and

assuming, by the proximal section of the inner embolic element, a predetermined shape to frame the aneurysm.