NASOLACRIMAL IMPLANTS AND RELATED METHODS FOR TEAR STIMULATION

• US 20170049619A1
• Filed: 11/08/2016
• Published: 02/23/2017
• Est. Priority Date: 06/16/2015
• Status: Active Grant

• Current Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Original Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Inventors: KAHOOK, Malik Y.
• Granted Patent: US 10,004,635 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/0026 Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: A61F 9/00772 Apparatus for restoration of tear ducts
• CPC Class Codes: A61H 23/02 with electric or magnetic drive
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36046 of the eye
• CPC Class Codes: A61N 1/36057 adapted for stimulating afferent nerves
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators
• CPC Class Codes: A61N 1/37229 Shape or location of the implanted or external antenna
• CPC Class Codes: A61N 1/3787 from an external energy source
• CPC Class Codes: A61N 2/004 specially adapted for a specific therapy
• CPC Class Codes: A61N 2007/0004 Applications of ultrasound therapy
• CPC Class Codes: A61N 5/0603 for treatment of body cavities
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092

Abstract

A device for inducing production of tears may include a body extending from a proximal end to a distal end. The body may be configured for insertion through a puncta of a subject. The device also may include a stimulus delivery mechanism positioned between the proximal end and the distal end and an induction coil operably coupled to the stimulus delivery mechanism. Further, the device may include an external controller wirelessly coupled to the induction coil for inductively transferring energy to the induction coil.

Claims

1. A device for inducing production of tears, comprising:

a body extending from a proximal end to a distal end, wherein the body is configured for insertion through a puncta of a subject; and

a stimulus delivery mechanism positioned between the proximal end and the distal end.

2. The device of claim 1, wherein the stimulus delivery mechanism includes a conductor.

3. The device of claim 2, further including a plurality of conductors positioned between the proximal end and the distal end of the body.

4. The device of claim 1, wherein an induction coil is operably coupled to the stimulus delivery mechanism.

5. The device of claim 1, wherein the body is configured for direct contact with a portion of a nasolacrimal drainage system of a subject.

6. The device of claim 1, further including a faceplate adjacent the proximal end of the body.

7. The device of claim 1, further including a sensor configured for sensing one or more of biochemical properties of tears, placement of the body, and operation of the stimulus delivery mechanism.

8. A device for inducing production of tears, comprising:

a body extending from a proximal end to a distal end, wherein the body is configured for insertion within a portion of a nasolacrimal drainage system of a subject;

a stimulus delivery mechanism positioned between the proximal end and the distal end;

a power receptor operably coupled to the stimulus delivery mechanism; and

an external controller coupled to the power receptor for transferring energy to the power receptor.

9. The device of claim 8, wherein the body includes an opening extending through a side wall of the body.

10. The device of claim 9, wherein at least a portion of the stimulus delivery mechanism is positioned within the opening.

11. The device of claim 9, wherein the body includes a plurality of openings extending through a side wall of the body.

12. The device of claim 8, wherein the stimulus delivery mechanism includes a conductor.

13. The device of claim 12, further including a plurality of conductors positioned between the proximal end and the distal end of the body.

14. The device of claim 8, further including a faceplate adjacent the proximal end of the body, wherein the faceplate has a faceplate diameter larger than a diameter of the proximal end of the body.

16. The device of claim 14, wherein the power receptor is in direct contact with the faceplate.

17. The device of claim 14, wherein the body and the faceplate include non-planar surfaces.

18. The device of claim 8, wherein the body is tapered such that the proximal end has a proximal end diameter and the distal end has a distal end diameter, wherein the distal end diameter is smaller than the proximal end diameter.

19. The device of claim 8, further including a lumen extending from the proximal end of the body to the distal end of the body.

20. The device of claim 8, wherein the body comprises a self-expandable mesh.

22. The device of claim 8, further including a sensor configured for sensing one or more of biochemical properties of tears, placement of the body, and operation of the stimulus delivery mechanism.

15. (canceled)

21. (canceled)

23-30. -30. (canceled)