METHOD FOR MAKING IMPLANTABLE LEAD

• US 20170054263A1
• Filed: 11/07/2016
• Published: 02/23/2017
• Est. Priority Date: 09/07/2012
• Status: Active Grant

• Current Assignee: Tsinghua University
• Original Assignee: Tsinghua University
• Inventors: Li, Lu-Ming, Jiang, Chang-Qing, Hao, Hong-Wei
• Granted Patent: US 10,155,106 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/086 Magnetic resonance imaging [MRI] compatible leads
• CPC Class Codes: H01R 13/6599 Dielectric material made conductive, e.g. plastic material coated with metal
• CPC Class Codes: H01R 2201/12 for medicine and surgery
• CPC Class Codes: H01R 24/58 Contacts spaced along longitudinal axis of engagement
• CPC Class Codes: Y10T 29/49208 by assembling plural parts

Abstract

A method for making an implantable lead is related. A pipe is provided. The pipe includes a first end portion, a second end portion opposite to the first end portion, and a middle portion connecting the first end portion and the second end portion. A flexible conductive layer is formed on the middle portion of the pipe. At least one contactor is applied on the first end portion of the pipe. At least one connector is applied on the second end portion of the pipe. At least one wire is placed in the pipe to electrically connect the at least one contactor and the at least one connector.

Claims

1. A method for making an implantable lead, the method comprising:

providing a pipe comprising a first end portion, a second end portion opposite to the first end portion, and a middle portion connecting the first end portion and the second end portion;

forming a flexible conductive layer on the middle portion of the pipe, the flexible conductive layer having a mesh structure with a plurality of flexible conductive wires;

applying at least one contactor on the first end portion of the pipe;

applying at least one connector on the second end portion of the pipe; and

electrically connecting the at least one contactor and the at least one connector with at least one connecting wire inside of the pipe.

2. The method of claim 1, wherein the pipe is made of a flexible material selected from the group consisting of polyurethane, silicone rubber, and nylon.

3. The method of claim 1, wherein forming the flexible conductive layer on the middle portion of the pipe comprises coating a paste of carbon nanotubes or graphene, depositing a layer of carbon nanotubes or graphene, or wrapping a film, a ribbon, a fiber, a yarn or a wire of carbon nanotubes or graphene on the middle portion of the pipe.

4. The method of claim 1, wherein the flexible conductive layer is formed on an outer surface of the pipe, an inner surface of the pipe, embedded in a side wall of the pipe, or combinations thereof.

7. The method of claim 1, wherein the flexible conductive layer has a hollow and undivided shape.

9. The method of claim 1, wherein the flexible conductive layer is formed to have a thickness gradient.

10. The method of claim 1, wherein a thickness of the flexible conductive layer is in a range from about 1 micrometer to about 2 millimeters.

11. The method of claim 1, wherein an average line resistance ratio of the flexible conductive layer is less than 20 Ω

/mm.

12. The method of claim 1, wherein the at least one contactor comprises a material selected from the group consisting of platinum, platinum alloy, iridium, iridium alloy, titanium, titanium alloy, tungsten, stainless steel, carbon nanotubes, carbon fiber, and conductive polymer.

14. The method of claim 1, wherein an average resistivity of the at least one contactor is greater than 10⁻

6 Ω

·

m.

21. The method of claim 1, further comprising:

extending a portion of the at least one connecting wire out of the pipe to form an exposed portion.

22. The method of claim 21, further comprising:

making a groove around the pipe; and

placing the exposed portion in the groove.

23. The method of claim 21, wherein applying the at least one contactor on the first end portion of the pipe comprises wrapping the at least one contactor on the exposed portion.

24. The method of claim 23, wherein the at least one contactor is selected from the group consisting of carbon nanotube film, carbon fiber, and a combination thereof.

25. The method of claim 23, further comprising:

folding the exposed portion to form a U-shaped configuration; and

sandwiching the exposed portion between two layers of the at least one contactor.

5. (canceled)

6. (canceled)

8. (canceled)

13. (canceled)

15-20. -20. (canceled)

26. A method for making an implantable lead, the method comprising:

providing a pipe comprising a first end portion, a second end portion opposite to the first end portion, and a middle portion connecting the first end portion and the second end portion;

forming a flexible conductive layer on the middle portion of the pipe, the flexible conductive layer comprising a mesh structure with a plurality of flexible conductive wires;

applying at least one connector on the second end portion of the pipe;

extending at least one connecting wire inside the pipe and an exposed portion of the at least one connecting wire out of the pipe at the first end portion;

wrapping at least one contactor on the exposed portion to electrically connect the at least one contactor with the at least one connecting wire; and

electrically connecting the at least one connector with the at least one connecting wire.