Electrocardiogram Device and Methods

• US 20170055863A1
• Filed: 08/30/2016
• Published: 03/02/2017
• Est. Priority Date: 08/31/2015
• Status: Active Grant

• Current Assignee: Ventrilink Corporation
• Original Assignee: Ventrilink Corporation
• Inventors: Baumann, Eric, Korzinov, Lev, Churchville, David
• Granted Patent: US 10,524,680 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/113 occurring during breathing
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

Devices and methods are described that provide improved diagnosis from the processing of physiological data. The methods include use of multiple algorithms and intelligently combing the results of multiple algorithms to provide a single optimized diagnostic result. The algorithms are adaptive and may be customized for particular data sets or for particular patients. Examples are shown with applications to electrocardiogram data, but the methods taught are applicable to many types of physiological data.

Claims

1. A method for the analysis of physiological data acquired from a patient said method comprising:

a) acquiring a first set of physiological data,

b) analyzing the first set of physiological data with at least two algorithms,

c) combining the diagnostic results of the at least two algorithms to provide a combined diagnostic result,

d) wherein the combined diagnostic result is determined by calculating a weighted average diagnosis wherein the weighted average diagnosis is the average of the diagnoses from each of the at least two algorithms weighted by a weighting factor of diagnoses from each of the at least two algorithms.

2. The method of claim 1 wherein the physiological data is an electrocardiogram.

3. The method of claim 1 wherein the weighting factor for each diagnosis from each of the at least two algorithms is a confidence estimate for the diagnosis.

4. The method of claim 1 wherein a true diagnosis for the patient is known and the weighting factors for each diagnosis are selected by a technician review such that the combined diagnostic result matches the true diagnosis.

5. The method of claim 1 wherein each algorithm was optimized for a subset of patients where certain similarity of physiological data is observed.

6. The method of claim 1 wherein a true diagnosis for the patient is known and the weighting factors for each diagnosis are adjusted by an adaptive algorithm.

7. The method of claim 1 wherein the first physiological data is acquired during a first time period, wherein a true diagnosis for the patient is known and the weighting factors for each diagnosis are selected by a technician review such that the combined diagnostic result matches the true diagnosis of the first physiological data and further acquiring a plurality of physiological data in a time period subsequent to the first time period and analyzing the plurality of physiological data using the weighting factors selected by a technician review of the first physiological data during the first time period.

8. A method for the analysis of physiological data acquired from a patient said method comprising:

a) acquiring a first set of physiological data,

b) analyzing the first set of physiological data with an algorithm having a plurality of input parameters,

c) wherein the plurality of input parameters are known to present different diagnoses when applied to the same data set,

d) reviewing the diagnosis results,

e) updating the parameters on the basis of the review,

f) reporting the diagnosis results.

9. The method of claim 8 wherein a true diagnosis for the patient is known and the parameters are selected by a technician review such that the diagnostic result matches the true diagnosis.

10. The method of claim 8 wherein the physiological data is an electrocardiogram.

11. The method of claim 8 wherein the parameters are optimized for a subset of patients where certain similarity of physiological data is observed.

12. The method of claim 8 wherein reviewing the diagnosis results further includes extrinsic data in the review

13. The method of claim 8 wherein the first physiological data is acquired during a first time period, wherein a true diagnosis for the patient is known and the weighting factors for each diagnosis are selected by a technician review such that the combined diagnostic result matches the true diagnosis of the first physiological data and further acquiring a plurality of physiological data after the first physiological data in a time period subsequent to the first time period and analyzing the plurality of physiological data acquired during the subsequent time period using the weighting factors selected by a technician review of the first physiological data acquired during the first time period.

14. The method of claim 13 wherein the first physiological data is an electrocardiogram.

15. A system for analysis of physiological data comprising:

a) a physiological data acquisition device that is attached to a patient and acquires physiological data from the patient,

b) a computing device connected to the physiological data acquisition device, the computing device programmed to;

i) acquire and store physiological data from the patient,

ii) calculate a clinically equivalent physiological data by comparing the physiological data from the patient with a database of stored physiological data and selecting indices of a portion of the data from the database of physiological data that is calculated to give the same diagnosis of the patient'"'"'s condition as the physiological data from the patient,

iii) present the clinically equivalent physiological data to a clinician for confirmation of the patient'"'"'s physiological condition.

16. The system of claim 15 where the physiological data is electrocardiogram data.

17. The system of claim 15 wherein the clinician is located remotely from the patient and the step of present the clinically equivalent physiological data to a clinician comprises sending to the clinician the indices and the clinically equivalent physiological data is then presented to the clinician by a computing device located at the location of the clinician by looking up and displaying those portions, corresponding to the transmitted indices, of a database of physiological data from a database stored on the computing device located at the location of the clinician.

18. The system of claim 16 wherein the clinician is located remotely from the patient and the step of present the clinically equivalent physiological data to a clinician comprises sending to the clinician the indices and the clinically equivalent physiological data is then presented to the clinician by a computing device located at the location of the clinician by looking up and displaying those portions, corresponding to the transmitted indices, of a database of physiological data from a database stored on the computing device located at the location of the clinician.

19. The system of claim 17 where the database of physiological data is physiological data acquired from subjects who are not the patient.

20. The system of claim 17 where the database of physiological data is physiological data acquired from the patient at an earlier time and stored by the computing device.

21. The system of claim 18 where the database of physiological data is physiological data acquired from subjects who are not the patient.

22. The system of claim 18 where the database of physiological data is physiological data acquired from the patient at an earlier time and stored by the computing device.

23. A method for analysis of physiological data comprising:

a) acquiring physiological data from a patient using a physiological data acquisition device that is attached to the patient, and,

b) storing the physiological data on a computing device connected to the physiological data acquisition device, and,

c) calculating a clinically equivalent physiological data by comparing the physiological data from the patient with a database of stored physiological data and selecting indices of a portion of the data from the database of physiological data that is calculated to give the same diagnosis of the patient'"'"'s condition as the physiological data from the patient, where the calculating is done on the computing device and the database is stored in a memory on the computing device, and,

d) presenting the clinically equivalent physiological data to a clinician for confirmation of the patient'"'"'s physiological condition.

24. The system of claim 23 where the physiological data is electrocardiogram data.

25. The system of claim 23 wherein the clinician is located remotely from the patient and presenting the clinically equivalent physiological data to a clinician comprises:

a) sending to the clinician the indices, and,

b) creating the clinically equivalent physiological data by a computing device located at the location of the clinician by looking up and displaying those portions, corresponding to the transmitted indices, of a database of physiological data from a database stored on the computing device located at the location of the clinician.

26. The system of claim 24 wherein the clinician is located remotely from the patient and presenting the clinically equivalent physiological data to a clinician comprises:

a) sending to the clinician the indices, and,

b) creating the clinically equivalent physiological data by a computing device located at the location of the clinician by looking up and displaying those portions, corresponding to the transmitted indices, of a database of physiological data from a database stored on the computing device located at the location of the clinician.

27. The system of claim 23 where the database of physiological data is physiological data acquired from subjects who are not the patient.

28. The system of claim 23 where the database of physiological data is physiological data acquired from the patient at an earlier time and stored by the computing device.

29. The system of claim 24 where the database of physiological data is physiological data acquired from subjects who are not the patient.

30. The system of claim 24 where the database of physiological data is physiological data acquired from the patient at an earlier time and stored by the computing device.