FOAMABLE SUNSCREEN FORMULATION

• US 20170100310A1
• Filed: 12/22/2016
• Published: 04/13/2017
• Est. Priority Date: 10/11/2011
• Status: Active Grant

• Current Assignee: Fallien Cosmeceuticals Ltd
• Original Assignee: Fallien Cosmeceuticals Ltd
• Inventors: MILORA, David J., FALLICK, Harry
• Granted Patent: US 10,154,946 B2
• Time in Patent Office: Days
• CPC Class Codes: A61K 2800/21 Emulsions characterized by droplet sizes below 1 micron
• CPC Class Codes: A61K 2800/52 Stabilizers
• CPC Class Codes: A61K 8/0241 Containing particulates characterized by their shape and/or structure see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/27 Zinc; Compounds thereof
• CPC Class Codes: A61K 8/29 Titanium; Compounds thereof
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61K 8/375 the alcohol moiety containing more than one hydroxy group
• CPC Class Codes: A61K 8/4993 Derivatives containing from 2 to 10 oxyalkylene groups
• CPC Class Codes: A61K 8/60 Sugars; Derivatives thereof
• CPC Class Codes: A61K 8/731 Cellulose; Quaternized cellulose derivatives
• CPC Class Codes: A61K 8/8147 Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/8152 Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/8176 Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/85 Polyesters
• CPC Class Codes: A61K 8/86 Polyethers
• CPC Class Codes: A61K 8/87 Polyurethanes
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Abstract

The present application relates to sunscreen formulations, including foamable sunscreen formulations, that comprise zinc oxide and titanium dioxide particles, suitably in the size range of about 1-100 nm. The compositions suitably produce a minimal residual whitening effect when applied to a skin surface.

Claims

1. A foamable sunscreen formulation comprising:

a) about 1 wt % to about 25 wt % zinc oxide particles having a primary particle size of about 5 nm to about 500 nm;

b) about 0.1 wt % to about 10 wt % emulsion stabilizer;

c) about 0.1 wt % to about 25 wt % skin conditioner;

d) about 1 wt % to about 10 wt % emulsifier;

e) about 0.1 wt % to about 10 wt % suspending agent; and

f) the remainder water, wherein the formulation produces a minimal residual whitening effect when applied to a skin surface.

2. The foamable sunscreen formulation of claim 1, comprising about 10 wt % to about 15 wt % zinc oxide particles.

3. The foamable sunscreen formulation of claim 1, comprising zinc oxide particles having a primary particle size of about 10 nm to about 200 nm.

4. The foamable sunscreen formulation of claim 1, wherein the emulsion stabilizer is selected from the group consisting of microcrystalline cellulose, cellulose gum, and combinations thereof.

5. The foamable sunscreen formulation of claim 1, wherein the skin conditioner is selected from the group consisting of C_12-15 alkyl benzoate, octyldodecyl neopentanoate, butyl octyl salicylate, caprylyl glycol, glycerin, and combinations thereof.

6. The foamable sunscreen formulation of claim 1, wherein the emulsifier is selected from the group consisting of glyceryl stearate, ceteareth-20, polysorbate 80, and combinations thereof.

7. The foamable sunscreen formulation of claim 1, wherein the suspending agent is selected from the group consisting of polyhydroxystearic acid, methyl methacrylate, crosspolymer and combinations thereof.

8. The foamable sunscreen formulation of claim 1, further comprising about 0.5 wt % to about 3 wt % film former, wherein the film former is selected from the group consisting of polyurethane-2, polymethyl methacrylate, tricontanyl poly(vinyl pyrollidone) (PVP), and combinations thereof.

9. The foamable sunscreen formulation of claim 1, further comprising about 0.01 wt % to about 1 wt % iron oxide particles.

10. The foamable sunscreen formulation of claim 1, wherein the zinc oxide particles have a primary particle size of about 10 nm to about 100 nm.

11. A foamable sunscreen formulation consisting essentially of:

a) about 1 wt % to about 25 wt % active particles having a primary particle size of about 5 nm to about 500 nm;

b) about 0.1 wt % to about 10 wt % emulsion stabilizer;

c) about 0.1 wt % to about 25 wt % skin conditioner;

d) about 1 wt % to about 10 wt % emulsifier;

e) about 0.1 wt % to about 10 wt % suspending agent; and

f) the remainder water, wherein the formulation produces a minimal residual whitening effect when applied to a skin surface.

12. The foamable sunscreen formulation of claim 11, wherein the wt % of active particles is about 10 wt % to about 15 wt %.

13. The foamable sunscreen formulation of claim 11, wherein the active particles have a primary particle size of about 10 nm to about 200 nm.

14. The foamable sunscreen formulation of claim 11, wherein the emulsion stabilizer is selected from the group consisting of microcrystalline cellulose, cellulose gum, and combinations thereof.

15. The foamable sunscreen formulation of claim 11, wherein the skin conditioner is selected from the group consisting of C_12-15 alkyl benzoate, octyldodecyl neopentanoate, butyl octyl salicylate, caprylyl glycol, glycerin, and combinations thereof.

16. The foamable sunscreen formulation of claim 11, wherein the emulsifier is selected from the group consisting of glyceryl stearate, ceteareth-20, polysorbate 80, and combinations thereof.

17. The foamable sunscreen formulation of claim 11, wherein the suspending agent is selected from the group consisting of polyhydroxystearic acid, methyl methacrylate crosspolymer, and combinations thereof.

18. The foamable sunscreen formulation of claim 11, further consisting essentially of about 0.5 wt % to about 3 wt % film former, wherein the film former is selected from the group consisting of polyurethane-2, polymethyl methacrylate, tricontanyl poly(vinyl pyrollidone) (PVP), and combinations thereof.

19. The foamable sunscreen formulation of claim 11, further consisting essentially of about 0.01 wt % to about 1 wt % iron oxide particles.

20. The foamable sunscreen formulation of claim 11, wherein the active particles have a primary particle size of about 10 nm to about 100 nm.

21. A foamable sunscreen formulation comprising:

a) about 1 wt % to about 25 wt % zinc oxide particles having a primary particle size of about 5 nm to about 500 nm;

c) about 0.1 wt % to about 5 wt % microcrystalline cellulose and about 0.1 wt % to about 5 wt % cellulose gum;

d) about 15 wt % to about 20 wt % C_12-15 alkyl benzoate, about 0.1 wt % to about 5 wt % octyldodecyl neopentanoate, and about 0.1 wt % to about 5 wt % butyl octyl salicylate;

e) about 0.1 wt % to about 5 wt % glyceryl stearate, about 0.1 wt % to about 5 wt % ceteareth-20, and about 0.1 wt % to about 5 wt % polysorbate 80;

f) about 0.1 wt % to about 5 wt % polyhydroxystearic acid and about 0.1 wt % to about 5 wt % methyl methacrylate crosspolymer;

g) about 0.1 wt % to about 3 wt % polyurethane-2, about 0.1 wt % to about 3 wt % polymethyl methacrylate, and about 0.1 wt % to about 3 wt % tricontanyl PVP film; and

i) about 50 wt % to about 60 wt % water, wherein the formulation produces a minimal residual whitening effect when applied to a skin surface.

22. The foamable sunscreen formulation of claim 21, further comprising about 0.01 wt % to about 1 wt % iron oxide particles.