COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID AND A HYDROXYL COMPOUND AND METHODS OF USE THEREOF
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Abstract
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
67 Citations
29 Claims
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1-9. -9. (canceled)
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10. A composition comprising a hydroxyl compound and eicosapentaenoate or a pharmaceutically acceptable salt or ester thereof, wherein the hydroxyl compound is:
a compound of Formula I; - View Dependent Claims (11, 12, 13, 14, 15, 16)
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17. A method of treating a cardiovascular-related disease or disorder in a subject comprising administering to the subject a composition comprising a hydroxyl compound and a composition comprising at least about 80%, by weight of all fatty acids present, eicosapentaenoate or a pharmaceutically acceptable salt or ester thereof, wherein the hydroxyl compound is:
a compound of Formula I; - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A method of treating a cardiovascular-related disease or disorder in a subject receiving therapy including a hydroxyl compound, the method comprising administering to the subject a composition comprising at least about 80%, by weight of all fatty acids present, eicosapentaenoate or a pharmaceutically acceptable salt or ester thereof, wherein the hydroxyl compound is:
a compound of Formula I; - View Dependent Claims (28, 29)
Specification