OPHTHALMIC IMPLANT FOR DELIVERING THERAPEUTIC SUBSTANCES
First Claim
1. A therapeutic device configured to be at least partially implanted in an eye, the device comprising:
- a porous structure positioned in fluid communication with an outlet of the device;
a reservoir having a volume sized to contain one or more therapeutic agents and to be in fluid communication with the outlet through the porous structure;
a retention structure positioned near a proximal end region of the device, the retention structure comprising a narrowed portion and a flanged portion extending proximally from the narrowed portion;
an access portion opening extending through the retention structure leading into the reservoir; and
a pre-molded, penetrable barrier configured to be repeatedly penetrated positioned within and oversized relative to the access portion opening.
1 Assignment
0 Petitions
Accused Products
Abstract
Described are implantable therapeutic devices, systems and methods to treat a patient. The device includes a hollow refillable housing for implantation within the posterior segment of an eye through a penetration in the sclera including a proximal retention structure protruding outward from a proximal end region of the housing, an access portion opening, and a penetrable barrier positioned at least in part within the access portion opening, the penetrable barrier configured to be repeatedly penetrated. A rigid porous structure is positioned within a region of the housing away from the access portion opening into a reservoir chamber extends along an axis between the penetrable barrier and the porous structure includes a volume sized to deliver therapeutic amounts of a therapeutic agent to the eye for an extended period of time. A cover is coupled to at least an upper surface of the proximal retention structure.
19 Citations
19 Claims
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1. A therapeutic device configured to be at least partially implanted in an eye, the device comprising:
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a porous structure positioned in fluid communication with an outlet of the device; a reservoir having a volume sized to contain one or more therapeutic agents and to be in fluid communication with the outlet through the porous structure; a retention structure positioned near a proximal end region of the device, the retention structure comprising a narrowed portion and a flanged portion extending proximally from the narrowed portion; an access portion opening extending through the retention structure leading into the reservoir; and a pre-molded, penetrable barrier configured to be repeatedly penetrated positioned within and oversized relative to the access portion opening. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification