METHODS AND SYSTEMS FOR THE DELIVERY OF DISSOLVED GASES AND DE-GASSING MEDICAL FLUID LINES

• US 20170173247A1
• Filed: 12/21/2016
• Published: 06/22/2017
• Est. Priority Date: 12/21/2015
• Status: Active Grant

• Current Assignee: Transluminal Systems, LLC
• Original Assignee: Hybernia Medical, LLC
• Inventors: Choi, Jae H., Pile-Spellman, John
• Granted Patent: US 10,773,009 B2
• Time in Patent Office: Days
• CPC Class Codes: A61M 1/1603 Regulation parameters
• CPC Class Codes: A61M 1/1629 with integral heat exchanger
• CPC Class Codes: A61M 1/1698 Blood oxygenators with or without heat-exchangers intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/32 Oxygenators without membranes
• CPC Class Codes: A61M 1/3613 Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
• CPC Class Codes: A61M 1/3626 Gas bubble detectors
• CPC Class Codes: A61M 1/363 Degassing by using vibrations
• CPC Class Codes: A61M 1/3638 with a vapour trap
• CPC Class Codes: A61M 1/3652 using gas, e.g. air
• CPC Class Codes: A61M 2202/0225 Carbon oxides, e.g. Carbon dioxide
• CPC Class Codes: A61M 2202/0275 Nitric oxide [NO]
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/36 related to heating or cooling
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 5/14 Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor

Abstract

A method and system for infusing medical liquid with gasses, the system comprising a gas source, a vacuum pump, a temperature-controlled container including a fluid reservoir coupled to the gas source and the vacuum pump, a heating and cooling system, and a sonicator, and a controller configured to de-gas a liquid in the fluid reservoir by activating the vacuum pump, re-gas the liquid in the fluid reservoir by releasing gas from the gas source to the fluid reservoir via a first fluid line, and deliver the re-gassed liquid from the fluid reservoir to a catheter via a second fluid line.

Claims

1. A system for infusing medical liquid with gasses, the system comprising:

a gas source;

a vacuum pump;

a temperature-controlled container including a fluid reservoir coupled to the gas source and the vacuum pump, a heating and cooling system, and a sonicator; and

a controller configured to;

de-gas a liquid in the fluid reservoir by activating the vacuum pump;

re-gas the liquid in the fluid reservoir by releasing gas from the gas source to the fluid reservoir via a first fluid line; and

deliver the re-gassed liquid from the fluid reservoir to a catheter via a second fluid line.

2. The system of claim 1 wherein the controller is further configured to de-gas the liquid in the fluid reservoir by enabling the heating and cooling system to heat the fluid reservoir, and activating the sonicator to sonificate the fluid reservoir.

3. The system of claim 1 wherein the controller is further configured to re-gas the liquid in the fluid reservoir by enabling the heating and cooling system to cool the fluid reservoir, and activating the sonicator to sonificate the fluid reservoir.

4. The system of claim 1 wherein the gas comprises a gas selected from the group consisting of oxygen, carbon dioxide, and nitric oxide.

5. The system of claim 1 further comprising sensors to detect bubbles, gas concentration, and temperature of the liquid.

6. The system of claim 1 further comprising a device that flushes the first fluid line and the second fluid line with safe gases.

7. The system of claim 6 wherein the safe gases comprise a gas that is quickly metabolized, highly soluble, and non-toxic.

8. The system of claim 6 wherein the safe gases comprise a gas selected from the group consisting of carbon dioxide and oxygen.

9. The system of claim 1 wherein the controller is further configured to flush the first fluid line and the second fluid line with the liquid subsequent to de-gassing the liquid.

10. Non-transitory computer readable media comprising program code that when executed by a programmable processor causes execution of a method for infusing medical liquid with gasses, the computer readable media comprising:

computer program code for de-gassing a liquid in a fluid reservoir by activating a vacuum pump, the fluid reservoir coupled to a gas source and the vacuum pump, and is comprised in a temperature-controlled container that includes a heating and cooling system and a sonicator;

computer program code for re-gassing the liquid in the fluid reservoir by releasing gas from the gas source to the fluid reservoir via a first fluid line; and

computer program code for delivering the re-gassed liquid from the fluid reservoir to a catheter via a second fluid line.

11. The non-transitory computer readable media of claim 10 further comprising computer program code for de-gassing the liquid in the fluid reservoir by enabling the heating and cooling system to heat the fluid reservoir and activating the sonicator to sonificate the fluid reservoir.

12. The non-transitory computer readable media of claim 10 further comprising computer program code for re-gassing the liquid in the fluid reservoir by enabling the heating and cooling system to cool the fluid reservoir, and activating the sonicator to sonificate the fluid reservoir.

13. The non-transitory computer readable media of claim 10 wherein the gas comprises a gas selected from the group consisting of oxygen, carbon dioxide, and nitric oxide.

14. The non-transitory computer readable media of claim 10 further comprising computer program code for detecting bubbles, gas concentration, and temperature of the liquid.

15. The non-transitory computer readable media of claim 10 further comprising computer program code for flushing the first fluid line and the second fluid line with the liquid subsequent to de-gassing the liquid.