SOLID-FORMING LOCAL ANESTHETIC FORMULATIONS FOR PAIN CONTROL
First Claim
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1. A solid forming local anesthetic formulation, comprising:
- lidocaine,tetracaine,from about 10 wt % to about 18 wt % polyvinyl alcohol,from about 30 wt % to about 50 wt % water, andan emulsifying agent,wherein the water to polyvinyl alcohol weight ratio (w/w) is greater than 2.4.
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Abstract
Solid-forming local anesthetic formulations for pain control can include a lidocaine base and tetracaine base, polyvinyl alcohol, water, and an emulsifier. The formulation can be prepared to be in a semi-solid state prior to application to a skin surface, can form a soft solidified layer after application, and can provide pain relief when applied to a skin surface proximate a pain site.
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Citations
20 Claims
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1. A solid forming local anesthetic formulation, comprising:
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lidocaine, tetracaine, from about 10 wt % to about 18 wt % polyvinyl alcohol, from about 30 wt % to about 50 wt % water, and an emulsifying agent, wherein the water to polyvinyl alcohol weight ratio (w/w) is greater than 2.4. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A solid forming local anesthetic formulation, comprising:
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a eutectic mixture of lidocaine and tetracaine, from about 10 wt % to about 18 wt % polyvinyl alcohol, from about 30 wt % to about 50 wt % water, petrolatum, and sorbitan monostearate, wherein the water to polyvinyl alcohol weight ratio (w/w) is greater than 2.4. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification