DISPOSABLE DIAGNOSTIC DEVICE WITH VOLUMETRIC CONTROL OF SAMPLE AND REAGENTS AND METHOD OF PERFORMING A DIAGNOSIS THEREWITH
First Claim
1. A disposable diagnostic device, comprising:
- an upper surface having a sample inlet opening;
a lower surface;
a central body disposed between said upper and lower surfaces, said central body having an inlet port, a sample receiving chamber, an analysis chamber and a fluid channel extending between said sample receiving chamber and said analysis chamber;
a rupturable fluid dispensing member operably fixed to said central body and containing a fluid therein for selective fluid communication with said sample receiving chamber; and
a valve member disposed between said upper and lower surfaces, said valve member having a sample through port and a fluid passage, said valve member being selectively moveable between an unactuated closed state to an actuated open state, while in said unactuated closed state, said fluid passage being out of fluid communication with said sample receiving chamber and said sample through port being registered with said sample inlet opening of said upper surface and with said sample receiving chamber of said central body to allow a sample to be disposed into said sample receiving chamber, and while in said actuated open state, said fluid passage being moved into fluid communication with said sample receiving chamber to bring said fluid within said fluid dispensing member, upon being ruptured, into fluid communication with the sample disposed in said sample receiving chamber, wherein said fluid readily flows through said inlet port, through said fluid passage to said sample receiving chamber to transport the sample throughout said fluid channel to said analysis chamber.
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0 Petitions
Accused Products
Abstract
A single-use, consumable diagnostic cartridge and method of performing a diagnostic test are provided. The cartridge has a sample inlet opening, an inlet port, a sample receiving chamber, an analysis chamber and a fluid channel extending between the sample receiving chamber and analysis chamber. A rupturable blister contains a fluid for selective mixing with a sample selectively disposed in the sample receiving chamber. A valve member, having a sample through port and a fluid passage, is selectively moveable between closed and open states. In the closed state, the fluid passage is out of fluid communication with the sample, and the sample through port is registered with the sample inlet opening and the sample receiving chamber. In the open state, the fluid passage extends between the inlet port and the sample receiving chamber to allow fluid dispelled from the blister to transport the sample to the analysis chamber.
10 Citations
18 Claims
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1. A disposable diagnostic device, comprising:
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an upper surface having a sample inlet opening; a lower surface; a central body disposed between said upper and lower surfaces, said central body having an inlet port, a sample receiving chamber, an analysis chamber and a fluid channel extending between said sample receiving chamber and said analysis chamber; a rupturable fluid dispensing member operably fixed to said central body and containing a fluid therein for selective fluid communication with said sample receiving chamber; and a valve member disposed between said upper and lower surfaces, said valve member having a sample through port and a fluid passage, said valve member being selectively moveable between an unactuated closed state to an actuated open state, while in said unactuated closed state, said fluid passage being out of fluid communication with said sample receiving chamber and said sample through port being registered with said sample inlet opening of said upper surface and with said sample receiving chamber of said central body to allow a sample to be disposed into said sample receiving chamber, and while in said actuated open state, said fluid passage being moved into fluid communication with said sample receiving chamber to bring said fluid within said fluid dispensing member, upon being ruptured, into fluid communication with the sample disposed in said sample receiving chamber, wherein said fluid readily flows through said inlet port, through said fluid passage to said sample receiving chamber to transport the sample throughout said fluid channel to said analysis chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of performing a diagnostic test on a fluid sample via a disposable diagnostic cartridge, comprising:
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disposing a sample through an inlet opening in a cover of the disposable diagnostic cartridge, through a sample through port of a translatable valve member of the disposable diagnostic cartridge, and into a sample receiving chamber of the disposable diagnostic cartridge; translating the valve member from an unactuated closed state to an actuated open state to isolate a precise volume of the sample in the sample receiving chamber; rupturing a blister of the disposable diagnostic cartridge and causing fluid to flow from the blister to carry the sample through a fluidic channel in the disposable diagnostic cartridge to an analysis chamber of the disposable diagnostic cartridge; and analyzing the sample while in the analysis chamber of the disposable diagnostic cartridge. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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Specification