METHOD AND APPARATUS FOR ATRIAL ARRHYTHMIA EPISODE DETECTION

• US 20180028082A1
• Filed: 02/18/2016
• Published: 02/01/2018
• Est. Priority Date: 02/18/2015
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: SARKAR, Shantanu, HANSEN, Daniel L., NEITZELL, Grant A., REILAND, Jerry D., WYSZYNSKI, Ryan
• Granted Patent: US 10,492,706 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61N 1/3624 occurring in the atrium, i.e. atrial tachycardia
• CPC Class Codes: A61N 1/36507 controlled by gradient or slope of the heart potential
• CPC Class Codes: A61N 1/36592 controlled by the heart rate variability
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

Techniques and devices for implementing the techniques for adjusting atrial arrhythmia detection based on analysis of one or more P-wave sensing windows associated with one or more R-waves. An implantable medical device may determine signal characteristics of the cardiac signal within the P-wave sensing window, determine whether the cardiac signal within the sensing window corresponds to a P-wave based on the determined signal characteristics, determine a signal to noise ratio of the cardiac signal within the sensing window, update the arrhythmia score when the P wave is identified in the sensing window and the determined signal to noise ratio satisfies a signal to noise threshold.

Claims

1. An implantable medical device for determining an atrial arrhythmia event within a cardiac signal, comprising:

a plurality of electrodes configured to sense the cardiac signal; and

a processor configured to identify one or more R-waves within the sensed cardiac signal, determine an atrial arrhythmia score for identifying the arrhythmia event based at least on the one or more R-waves, determine a sensing window associated with the one or more R-waves and having a first portion and a second portion, determine signal characteristics of the cardiac signal within the sensing window, determine whether the cardiac signal within the sensing window corresponds to a P-wave based on the determined signal characteristics, determine a signal to noise ratio of the cardiac signal within the sensing window, update the arrhythmia score when the P-wave is identified in the sensing window and the determined signal to noise ratio satisfies a signal to noise threshold.

2. The medical device of claim 1, wherein the processor is further configured to determine whether to delivery an arrhythmia therapy based on the updated arrhythmia score.

3. The medical device of claim 1, wherein the processor is further configured to determine a second derivative signal of the cardiac signal within the sensing window, determine a first maximum amplitude of the second derivative signal within the first portion of the sensing window and a second maximum amplitude of the second derivative signal within the second portion of the sensing window, compare the first maximum amplitude with the second maximum amplitude, and determine whether the signal to noise ratio satisfies the signal to noise threshold based on the comparison.

4. The medical device of claim 3, wherein the comparing comprises determining whether the second maximum amplitude is greater than a multiple of the first maximum amplitude and the signal to noise ratio satisfies the signal to noise ratio threshold when the second maximum amplitude is greater than the multiple of the first maximum amplitude.

5. The medical device of claim 1, wherein the processor is further configured to determine a second derivative signal of the cardiac signal within the sensing window, determine a first minimum amplitude of the second derivative signal within the first portion of the sensing window and a second minimum amplitude of the second derivative signal within the second portion of the sensing window, compare the first minimum amplitude with the second minimum amplitude, determine whether the signal to noise ratio satisfies the signal to noise threshold based on the comparison.

6. The medical device of claim 1, wherein the comparing comprises determining whether the second minimum amplitude is less than a multiple of the first minimum amplitude and the signal to noise ratio satisfies is satisfied the signal to noise ratio threshold when the second minimum amplitude is less than the multiple of the first minimum amplitude.

7. The medical device of claim 1, wherein the processor is further configured to determine, in response to the P-wave being identified in the sensing window and the signal to noise ratio not satisfying the signal to noise threshold, whether the cardiac signal within the sensing window corresponds to one of a flutter event and a noise event, and update the arrhythmia score in response to the cardiac signal within the sensing window not corresponding to one of a flutter event and a noise event.

8. The medical device of claim 1, wherein the atrial arrhythmia event comprises one of an atrial tachycardia event and an atrial fibrillation event, the processor is further configured to increase, in response to the cardiac signal within the sensing window corresponding to a P-wave, a P-wave evidence counter for atrial fibrillation by a first predetermined amount and increase a P-wave evidence counter for atrial tachycardia by a second predetermined amount not equal to the first predetermined amount.

9. The medical device of claim 8, wherein the processor is further configured to update the arrhythmia score by at least one of withholding atrial arrhythmia detection based on at least one of the P-wave evidence counter for atrial tachycardia being greater than a first threshold or the P-wave evidence counter for atrial fibrillation being greater than a second threshold.

10. The medical device of claim 8, wherein at least one of a value of the P-wave evidence counter for atrial fibrillation, a value of the P-wave evidence counter for atrial tachycardia, a multiple of the value of the P-wave evidence counter for atrial fibrillation, or a multiple of the value of the P-wave evidence counter for atrial tachycardia is subtracted from the atrial arrhythmia score.

11. The medical device of claim 1, wherein the medical device comprises a subcutaneous device.

12. The medical device of claim 1, wherein the sensing window includes a first portion and a second portion, the first portion of the sensing window is a baseline portion and the second portion of the sensing window is a P-wave portion

13. The medical device of claim 1, wherein the processor is further configured to, in response to the P-wave being identified in the sensing window and the signal to noise ratio not satisfying the signal to noise threshold, determine whether the cardiac signal within the sensing window corresponds to an atrial flutter event, determine whether the cardiac signal within the sensing window corresponds to a noise event, and update the arrhythmia score in response to the cardiac signal within the sensing window not corresponding to an atrial flutter event and not corresponding to a noise event.

14. A method comprising:

sensing a cardiac signal on a plurality of electrodes;

identifying one or more R-waves within the sensed cardiac signal,

determining an atrial arrhythmia score for identifying the arrhythmia event based at least on the one or more R-waves,

determining a sensing window associated with the one or more R-waves,

determining signal characteristics of the cardiac signal within the sensing window,

determining whether the cardiac signal within the sensing window corresponds to a P-wave based on the determined signal characteristics,

determining a signal to noise ratio of the cardiac signal within the sensing window,

increasing, when the cardiac signal within the sensing window is determined to correspond to a P-wave and the determined signal to noise ratio satisfies a signal to noise threshold, a P-wave evidence counter for atrial fibrillation by a first predetermined amount;

increasing, when the cardiac signal within the sensing window is determined to correspond to a P-wave and the determined signal to noise ratio satisfies a signal to noise threshold, a P-wave evidence counter for atrial tachycardia by a second predetermined amount not equal to the first predetermined amount

updating the arrhythmia score based on at least one of the P-wave evidence counter for atrial fibrillation and the P-wave evidence counter for atrial tachycardia.

15. The method of claim 14, wherein updating the arrhythmia score comprises withholding atrial arrhythmia detection based on at least one of the P-wave evidence counter for atrial tachycardia being greater than a first threshold or the P-wave evidence counter for atrial fibrillation being greater than a second threshold.

16. The method of claim 14, wherein updating the arrhythmia score comprises at least one of a value of the P-wave evidence counter for atrial fibrillation, a value of the P-wave evidence counter for atrial tachycardia, a multiple of the value of the P-wave evidence counter for atrial fibrillation, or a multiple of the value of the P-wave evidence counter for atrial tachycardia is subtracted from the atrial arrhythmia score.

17. The method of claim 14, further comprising:

in response to the P-wave being identified in the sensing window and the signal to noise ratio not satisfying the signal to noise threshold, determining whether the cardiac signal within the sensing window corresponds to one of a flutter event and a noise event; and

updating the arrhythmia score in response to the cardiac signal within the sensing window not corresponding to one of a flutter event and a noise event.

18. The method of claim 14, further comprising:

in response to the P-wave being identified in the sensing window and the signal to noise ratio not satisfying the signal to noise threshold, determining whether the cardiac signal within the sensing window corresponds to an atrial flutter event;

determining whether the cardiac signal within the sensing window corresponds to a noise event; and

updating the arrhythmia score in response to the cardiac signal within the sensing window not corresponding to an atrial flutter event and not corresponding to a noise event.

19. The method of claim 14, further comprising:

identifying a first, baseline portion of the sensing window; and

identifying a second, P-wave portion of the sensing window,

wherein determining signal characteristics of the cardiac signal comprises determining signal characteristics of the cardiac signal within each of the first, baseline portion and the second, P-wave portion of the sensing window,

further wherein determining whether the cardiac signal within the sensing window corresponds to a P-wave comprises determining whether the cardiac signal within the sensing window corresponds to a P-wave based on the determined signal characteristics of each of the first, baseline portion and the second, P-wave portion of the sensing window.