Cell Preparations For Extemporaneous Use, Useful For Healing And Rejuvenation In Vivo
First Claim
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1. A medical separator system for preparation of a platelet concentrate, comprising:
- a tube being adapted to be centrifuged for a length of time and containing two additives, wherein said two additives include;
a thixotropic gel being adapted to separate blood components in whole blood to provide a platelet concentrate containing less than or equal to 1% hematocrit and a pellet containing more than or equal to 99% hematocrit by forming a barrier between plasma and erythrocytes when said tube is centrifuged; and
an anticoagulant being adapted to at least reduce coagulation of said whole blood.
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Abstract
The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides plasma or platelet-rich plasma alone or in cell combinations preparations for use in tissue regeneration and bone regeneration and pain reduction.
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30 Claims
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1. A medical separator system for preparation of a platelet concentrate, comprising:
a tube being adapted to be centrifuged for a length of time and containing two additives, wherein said two additives include; a thixotropic gel being adapted to separate blood components in whole blood to provide a platelet concentrate containing less than or equal to 1% hematocrit and a pellet containing more than or equal to 99% hematocrit by forming a barrier between plasma and erythrocytes when said tube is centrifuged; and an anticoagulant being adapted to at least reduce coagulation of said whole blood. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A medical separator system for preparation of a platelet concentrate, comprising:
a tube being adapted to be centrifuged for a length of time and containing two additives, wherein said two additives include; a thixotropic gel being adapted to separate blood components in whole blood to provide a platelet concentrate containing 2 or more times a normal level of platelets and growth factors compared to said whole blood and a pellet containing more than or equal to 99% hematocrit by forming a barrier between plasma and erythrocytes when said tube is centrifuged; and an anticoagulant being adapted to at least reduce coagulation of said whole blood. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A medical separator system for preparation of a platelet concentrate, comprising:
a tube being adapted to be centrifuged for a length of time and containing two additives, wherein said two additives include; a thixotropic gel being adapted to separate blood components in whole blood to provide a platelet concentrate containing less than or equal to 1% hematocrit by forming a barrier between plasma and erythrocytes when said tube is centrifuged, said platelet concentrate having 2 or more times a normal level of platelets and growth factors compared to said whole blood and having a platelet recovery of 95%±
5%; andan anticoagulant being adapted to at least reduce coagulation of said whole blood. - View Dependent Claims (23, 24, 25, 26, 27, 28)
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29. A medical separator system for preparation of a blood concentrate or a bone marrow concentrate, comprising:
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a tube being adapted to be centrifuged for a length of time and containing two additives, wherein said two additives include; a thixotropic gel being adapted to separate blood components in blood to provide a blood concentrate containing less than or equal to 1% hematocrit and a pellet containing more than or equal to 99% hematocrit by forming a barrier between plasma and erythrocytes when said tube is centrifuged; and an anticoagulant being adapted to at least reduce coagulation of said whole blood; wherein said tube contains between approximately 1 mL and approximately 3 mL of said thixotropic gel. - View Dependent Claims (30)
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Specification