SYSTEMS AND METHODS FOR MULTIFUNCTIONAL VOLUMETRIC FLUID CONTROL
First Claim
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1. A system for performing any one of hemodialysis, hemodiafiltration, hemofiltration, comprising:
- a controlled compliant flow path comprising a dialyzer;
at least a first pump in fluid communication with the controlled compliant flow path;
a common reservoir in fluid communication with the first pump, wherein the common reservoir contains any one of a dialysate, a filtrate, a volume of a physiologically compatible priming solution, a volume of a physiologically compatible solution to provide a bolus of fluid to a subject receiving treatment, a volume of physiologically compatible solution to provide solution for return of blood from an extracorporeal flow path to a subject receiving treatment, a volume of solution returned to the common reservoir from an extracorporeal flow path when blood from a subject is introduced to the extracorporeal flow path, and combinations thereof;
the at least first pump for selectively metering in and/or metering out fluid from the controlled compliant flow path; and
the at least first pump operable to control net fluid movement into and/or out of the controlled compliant flow path, wherein the at least first pump is operated by a controller applying an instantaneous rate of fluid removal to a control algorithm.
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Abstract
Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end.
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20 Claims
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1. A system for performing any one of hemodialysis, hemodiafiltration, hemofiltration, comprising:
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a controlled compliant flow path comprising a dialyzer; at least a first pump in fluid communication with the controlled compliant flow path;
a common reservoir in fluid communication with the first pump, wherein the common reservoir contains any one of a dialysate, a filtrate, a volume of a physiologically compatible priming solution, a volume of a physiologically compatible solution to provide a bolus of fluid to a subject receiving treatment, a volume of physiologically compatible solution to provide solution for return of blood from an extracorporeal flow path to a subject receiving treatment, a volume of solution returned to the common reservoir from an extracorporeal flow path when blood from a subject is introduced to the extracorporeal flow path, and combinations thereof;the at least first pump for selectively metering in and/or metering out fluid from the controlled compliant flow path; and the at least first pump operable to control net fluid movement into and/or out of the controlled compliant flow path, wherein the at least first pump is operated by a controller applying an instantaneous rate of fluid removal to a control algorithm. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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2. The system of claim Error! Reference source not found., wherein the controller applies the control algorithm to obtain a net volume of fluid added to and/or removed from a patient during therapy by an equation:
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Σ
i=0nXi=patient fluid balance;wherein n is a number of pumps fluidly connected to the controlled compliant flow path, i refers to a specific pump fluidly connected to the controlled compliant flow path, and Xi is volumetric flow rate of a pump in either an influx or efflux direction;
wherein is negative when pump i is operated in the efflux direction and positive when pump i is operated in an influx direction. - View Dependent Claims (3, 4)
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Specification