Functionally-Modified Oligonucleotides And Subunits Thereof
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Accused Products
Abstract
Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
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Citations
234 Claims
- 1. A compound having the structure of Formula (I):
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Specification