COMPOSITIONS AND DEVICES INCORPORATING WATER-INSOLUBLE THERAPEUTIC AGENTS AND METHODS OF THE USE THEREOF
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Abstract
Various aspects of the present invention provide compositions and implantable devices including a water-insoluble therapeutic agent solubilized in a matrix of a gallate-containing compound. Other aspects provide methods of manufacturing and using such compositions and devices
1 Citation
39 Claims
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1-19. -19. (canceled)
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20. A composition comprising:
a cream, paste, or gel comprising a gallate containing compound and a drug. - View Dependent Claims (24, 25, 26, 27, 28)
- 21. The composition of claim 21, wherein the gallate containing compound is selected from a group consisting of epi gallo catechin gallate, tannic acid and epi catechin gallate.
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29. A microparticle comprising
a polymeric matrix, a gallate containing compound, and water-insoluble therapeutic agent.
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34. A composition comprising:
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an aqueous solvent; a gallate containing compound; and water-insoluble therapeutic agent. - View Dependent Claims (35, 36, 37, 38, 39)
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Specification