INSULIN RECEPTOR PARTIAL AGONISTS
2 Assignments
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Accused Products
Abstract
Insulin dimers and insulin analog dimers that act as partial agonists at the insulin receptor are disclosed.
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94 Claims
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1-73. -73. (canceled)
- 74. A compound selected from the group consisting of
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78-81. -81. (canceled)
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82. An insulin dimer comprising:
(a) a first B29 or B28 Lys of a first insulin heterodimer molecule having a first A-chain polypeptide and first B-chain polypeptide and a second B29 or B28 Lys of a second insulin heterodimer having a second A-chain polypeptide and second B-chain polypeptide conjugated together by a bifunctional linker selected from the group consisting of;
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83-93. -93. (canceled)
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94. A compound having the following formula
Specification