METHODS AND COMPOSITIONS FOR BINDING VEGF
First Claim
1. A fusion polypeptide comprising two or more VEGF receptor immunoglobulin-like-type 2 domains fused with a dimerization polypeptide, wherein at least one of said two or more VEGF receptor immunoglobulin-like-type 2 domains is fused to an N-terminus of said dimerization polypeptide and at least another of said two or more VEGF receptor immunoglobulin-like-type 2 domains is fused to a C-terminus of said dimerization polypeptide.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention relates to fusion polypeptide compositions comprising immunoglobulin-type-2 binding domains of Vascular Endothelial Growth Factor Receptor, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.
6 Citations
53 Claims
- 1. A fusion polypeptide comprising two or more VEGF receptor immunoglobulin-like-type 2 domains fused with a dimerization polypeptide, wherein at least one of said two or more VEGF receptor immunoglobulin-like-type 2 domains is fused to an N-terminus of said dimerization polypeptide and at least another of said two or more VEGF receptor immunoglobulin-like-type 2 domains is fused to a C-terminus of said dimerization polypeptide.
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Specification