MIXED SALT COMPOSITIONS FOR PRODUCING ELEVATED AND SUSTAINED KETOSIS
First Claim
1. A composition for increasing ketone level in a subject, comprising:
- a beta-hydroxybutyrate mixed salt comprising at least two beta-hydroxybutyrate salts selected from the group consisting of;
10-70% by weight of sodium beta-hydroxybutyrate;
10-70% by weight of potassium beta-hydroxybutyrate;
10-70% by weight of calcium beta-hydroxybutyrate;
10-70% by weight of magnesium beta-hydroxybutyrate; and
a salt of one or more amino acids and beta-hydroxybutyrate,wherein the beta-hydroxybutyrate mixed salt is in solid and/or powder form.
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Accused Products
Abstract
Ketogenic compositions including a beta-hydroxybutyrate (BHB) mixed salt are formulated to induce or sustain ketosis in a subject to which the ketogenic compositions are administered. The BHB mixed salt is formulated to provide a biologically balanced set of cationic electrolytes, and is formulated to avoid detrimental health effects associated with imbalanced electrolyte ratios. A ketogenic composition includes BHB salts of at least sodium, potassium, calcium, and magnesium. The BHB salts may also include at least other component such as a BHB compound containing other cations, such as transition metal cations (e.g., zinc or iron), a BHB-amino acid salts, medium chain fatty acid source, vitamin D3, flavorant, or other excipient.
18 Citations
20 Claims
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1. A composition for increasing ketone level in a subject, comprising:
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a beta-hydroxybutyrate mixed salt comprising at least two beta-hydroxybutyrate salts selected from the group consisting of; 10-70% by weight of sodium beta-hydroxybutyrate; 10-70% by weight of potassium beta-hydroxybutyrate; 10-70% by weight of calcium beta-hydroxybutyrate; 10-70% by weight of magnesium beta-hydroxybutyrate; and a salt of one or more amino acids and beta-hydroxybutyrate, wherein the beta-hydroxybutyrate mixed salt is in solid and/or powder form. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A kit for use in increasing ketone level in a subject, comprising:
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a composition comprising a beta-hydroxybutyrate mixed salt comprising at least two beta-hydroxybutyrate salts selected from the group consisting of; 10-70% by weight of sodium beta-hydroxybutyrate; 10-70% by weight of potassium beta-hydroxybutyrate; 10-70% by weight of calcium beta-hydroxybutyrate; 10-70% by weight of magnesium beta-hydroxybutyrate; and a salt of one or more amino acids and beta-hydroxybutyrate; a container in which the composition is placed; and a measuring device configured to hold therein a unit dose, or fraction thereof, of the composition, wherein a unit dose of the composition contains about 1 g to about 50 g of beta-hydroxybutyrate mixed salt. - View Dependent Claims (12, 13, 14, 15, 16, 17)
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18. A method for increasing ketone level in a subject, comprising:
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administering or receiving a unit dose of a beta-hydroxybutyrate mixed salt comprising at least two beta-hydroxybutyrate salts selected from the group consisting of; 10-70% by weight of sodium beta-hydroxybutyrate; 10-70% by weight of potassium beta-hydroxybutyrate; 10-70% by weight of calcium beta-hydroxybutyrate; 10-70% by weight of magnesium beta-hydroxybutyrate; and a salt of one or more amino acids and beta-hydroxybutyrate, wherein the unit dose contains about 1 g to about 50 g of the beta-hydroxybutyrate mixed salt. - View Dependent Claims (19, 20)
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Specification