MULTI-STREAM DATA COLLECTION SYSTEM FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS

• US 20190261895A1
• Filed: 05/10/2019
• Published: 08/29/2019
• Est. Priority Date: 07/03/2008
• Status: Active Grant

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Corporation
• Inventors: Poeze, Jeroen, Lamego, Marcelo, Merritt, Sean, Dalvi, Cristiano, Vo, Hung, Bruinsma, Johannes, Lesmana, Ferdyan, Kiani, Massi Joe E., Olsen, Greg
• Granted Patent: US 10,376,190 B1
• Time in Patent Office: Days
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/146 for optical coupling
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/4875 Hydration status, fluid retention of the body
• CPC Class Codes: A61B 5/6816 Ear lobe
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/70 Means for positioning the patient in relation to the detecting, measuring or recording means
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor

Abstract

prepared that ranged from 0-55 mg/dL. Five samples were used as a training set and 20 samples were then used as a test population. As shown, embodiments of sensor 101 were able to obtain at least a standard deviation of 37 mg/dL in the training set and 32 mg/dL in the test population.

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Claims

1. (canceled)

2. A noninvasive optical physiological measurement device adapted to be worn by a wearer, the noninvasive optical physiological measurement device providing an indication of a physiological parameter of the wearer comprising:

one or more light emitters ;

a housing having a surface and a circular raised edge extending from the surface;

at least four detectors arranged on the surface and spaced apart from each other, the at least four detectors configured to output one or more signals responsive to light from the one or more light emitters attenuated by body tissue, the one or more signals indicative of a physiological parameter of the wearer; and

a light permeable cover arranged above at least a portion of the housing, the light permeable cover comprising a protrusion arranged to cover the at least four detectors.

3. The noninvasive optical physiological measurement device of claim 2, wherein the light permeable cover is attached to the housing and forms an airtight or substantially airtight seal enclosing the at least four detectors.

4. The noninvasive optical physiological measurement device of claim 3, wherein the circular raised edge creates a gap between the surface and the light permeable cover.

5. The noninvasive optical physiological measurement device of claim 3, wherein the housing provides noise shielding for the at least four detectors.

6. The noninvasive optical physiological measurement device of claim 5, wherein the light permeable cover comprises a conductive layer configured to shield the at least four detectors from noise.

7. The noninvasive optical physiological measurement device of claim 4, wherein the protrusion comprises a continuous protrusion.

8. The noninvasive optical physiological measurement device of claim 7, wherein the continuous protrusion comprises a convex protrusion.

9. The noninvasive optical physiological measurement device of claim 7, wherein the light permeable cover is comprised of a rigid material.

10. The noninvasive optical physiological measurement device of claim 9, wherein the light permeable cover is configured to be positioned between the at least four detectors and tissue of a user when the noninvasive optical physiological measurement device is worn by the user.

11. The noninvasive optical physiological measurement device of claim 10, wherein the light permeable cover is configured to press against and at least partially deform tissue of the user when the noninvasive optical physiological measurement device is worn by the user.

12. The noninvasive optical physiological measurement device of claim 11, wherein the light permeable cover is configured to act as a tissue shaper and conform tissue of the user to at least a portion of an external surface shape of the light permeable cover when the noninvasive optical physiological measurement device is worn by the user.

13. The noninvasive optical physiological measurement device of claim 12, wherein the light permeable cover is configured to reduce a mean path length of light traveling to the at least four detectors.

14. The noninvasive optical physiological measurement device of claim 12, wherein the at least four detectors are evenly spaced from one another.

15. The noninvasive optical physiological measurement device of claim 14, wherein the light permeable cover is configured to reduce a mean path length of light traveling to the at least four detectors.

16. The noninvasive optical physiological measurement device of claim 14, wherein the light permeable cover is configured to increase a signal to noise ratio of the noninvasive optical physiological measurement device.

17. The noninvasive optical physiological measurement device of claim 14, wherein the light permeable cover is configured to increase a signal strength per area of the at least four detectors.

18. The noninvasive optical physiological measurement device of claim 2, wherein the physiological parameter is pulse rate.

19. The noninvasive optical physiological measurement device of claim 2, wherein the physiological parameter is at least one of:

glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.

20. The noninvasive optical physiological measurement device of claim 2, wherein the noninvasive optical physiological measurement device is a disposable or a reusable device.

21. The noninvasive optical physiological measurement device of claim 2, wherein a first detector is arranged spaced apart from a second detector, and a third detector arranged spaced apart from a fourth detector.

22. The noninvasive optical physiological measurement device of claim 21, wherein the first detector is arranged across a central axis from the second detector and the third detector is arranged across the central axis from the fourth detector, wherein the first, second, third and fourth detectors form a cross pattern about the central axis.

23. The noninvasive optical physiological measurement device of claim 21, wherein the noninvasive optical physiological measurement device provides a variation in optical path length to the at least four detectors.

24. The noninvasive optical physiological measurement device of claim 2, wherein the noninvasive optical physiological measurement device is comprised as part of a mobile monitoring device.

25. The noninvasive optical physiological measurement device of claim 24, wherein the mobile monitoring device includes a touch-screen display.

26. A physiological monitoring system comprising:

the noninvasive optical physiological measurement device of claim 2; and

a processor configured to receive the one or more signals and communicate physiological measurement information to a mobile phone.

27. A noninvasive optical physiological measurement device adapted to be worn by a wearer providing an indication of a physiological parameter of the wearer comprising:

one or more light emitters;

a circular housing comprising a surface and a wall protruding from the surface;

at least four detectors arranged on the surface, wherein a first detector is arranged spaced apart from a second detector, and a third detector arranged spaced apart from a fourth detector; and

a cover of the circular housing comprising a lens portion, the lens portion comprising a protrusion in optical communication with the at least four detectors,

wherein the at least four detectors are configured to output one or more signals responsive to light from the one or more light emitters attenuated by body tissue, the one or more signals indicative of a physiological parameter of the wearer.

28. The noninvasive optical physiological measurement device of claim 27, wherein the first detector is arranged across a central axis from the second detector and the third detector is arranged across the central axis from the fourth detector, wherein the first, second, third and fourth detectors form a cross pattern about the central axis.

29. The noninvasive optical physiological measurement device of claim 27, wherein the at least four detectors are arranged in a grid pattern such that the first detector and the second detector are arranged across from each other on opposite sides of a central point along a first axis, and the third detector and the fourth detector are arranged across from each other on opposite sides of the central point along a second axis which is perpendicular to the first axis.

30. The noninvasive optical physiological measurement device of claim 28, wherein the physiological parameter is pulse rate.

31. The noninvasive optical physiological measurement device of claim 28, wherein the physiological parameter is at least one of:

glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.