MULTI-STREAM DATA COLLECTION SYSTEM FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS

• US 20200221978A1
• Filed: 03/25/2020
• Published: 07/16/2020
• Est. Priority Date: 07/03/2008
• Status: Active Grant

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Corporation
• Inventors: Poeze, Jeroen, Lamego, Marcelo, Merritt, Sean, Dalvi, Cristiano, Vo, Hung, Bruinsma, Johannes, Lesmana, Ferdyan, Kiani, Massi Joe E., Olsen, Greg
• Granted Patent: US 10,709,366 B1
• Time in Patent Office: Days
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/146 for optical coupling
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/4875 Hydration status, fluid retention of the body
• CPC Class Codes: A61B 5/6816 Ear lobe
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/70 Means for positioning the patient in relation to the detecting, measuring or recording means
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor

Abstract

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Claims

1. (canceled)

2. A noninvasive physiological parameter measurement device adapted to be worn by a wearer, the noninvasive physiological parameter measurement device comprising:

one or more light emitters;

a substrate having a surface;

a first set of photodiodes arranged on the surface and spaced apart from each other, wherein;

the first set of photodiodes comprises at least four photodiodes, and

the photodiodes of the first set of photodiodes are connected to one another in parallel to provide a first signal stream responsive to light from at least one of the one or more light emitters attenuated by body tissue;

a second set of photodiodes arranged on the surface and spaced apart from each other, wherein;

the second set of photodiodes comprises at least four photodiodes,

the photodiodes of the second set of photodiodes are connected to one another in parallel to provide a second signal stream responsive to light from at least one of the one or more light emitters attenuated by body tissue, and

at least one of the first signal stream or the second signal stream includes information usable to determine a physiological parameter of a wearer of the noninvasive physiological parameter measurement device;

a wall extending from the surface and configured to surround at least the first and second sets of photodiodes; and

a cover arranged to cover at least a portion of the surface of the substrate, wherein the cover comprises a protrusion that extends over all of the photodiodes of the first and second sets of photodiodes arranged on the surface, and wherein the cover is further configured to cover the wall.

3. The noninvasive physiological parameter measurement device of claim 2 further comprising preprocessing electronics including at least:

first preprocessing electronics configured to preprocess the first signal stream; and

second preprocessing electronics configured to preprocess the second signal stream.

4. The noninvasive physiological parameter measurement device of claim 3, wherein:

the first preprocessing electronics comprise at least a first amplifier configured to receive the first signal stream and at least amplify the first signal stream, and

the second preprocessing electronics comprise at least a second amplifier configured to receive the second signal stream and at least amplify the second signal stream.

5. The noninvasive physiological parameter measurement device of claim 4, wherein the preprocessing further comprises converting at least one of the first signal stream or the second signal stream from analog to digital.

6. The noninvasive physiological parameter measurement device of claim 4, wherein the protrusion comprises a convex protrusion, and wherein at least a portion the cover is comprised of a sufficiently rigid material to cause tissue of the wearer to conform to at least a portion of a shape of the cover.

7. The noninvasive physiological parameter measurement device of claim 6, wherein the physiological parameter comprises at least one of:

pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.

8. The noninvasive physiological parameter measurement device of claim 7, wherein at least part of the cover is light permeable.

9. The noninvasive physiological parameter measurement device of claim 7 further comprising:

one or more openings that allow light to pass through to the photodiodes of the first and second sets of photodiodes.

10. The noninvasive physiological parameter measurement device of claim 9, wherein the wall operably connects to the substrate on one side and operably connects to the cover on an opposite side.

11. The noninvasive physiological parameter measurement device of claim 10 further comprising:

a touch-screen display;

a strap configured to facilitate attachment of at least part of the noninvasive physiological parameter measurement device to an arm of the wearer; and

one or more processors configured to;

receive information responsive to at least one of the first signal stream or the second signal stream;

process the information to determine physiological parameter measurement information; and

cause communication of the physiological parameter measurement information to a user interface displayed on the touch-screen display.

12. The noninvasive physiological parameter measurement device of claim 11, wherein the attenuated light is reflected by the tissue.

13. The noninvasive physiological parameter measurement device of claim 12, wherein the one or more processors are further configured to:

cause transmission of the physiological parameter measurement information to at least one of;

a mobile phone, or a computer network.

14. The noninvasive physiological parameter measurement device of claim 13 further comprising:

a magnet configured to be used as a connecting mechanism.

15. A noninvasive physiological parameter measurement device comprising:

one or more light emitters;

a first set of photodiodes, the first set of photodiodes comprising at least four photodiodes, the photodiodes of the first set of photodiodes connected to one another in parallel to provide a first signal stream responsive to light from at least one of the one or more light emitters attenuated by body tissue;

a second set of photodiodes, the second set of photodiodes comprising at least four photodiodes, the photodiodes of the second set of photodiodes connected to one another in parallel to provide a second signal stream responsive to light from at least one of the one or more light emitters attenuated by body tissue;

a wall configured to surround at least the first and second sets of photodiodes;

a protrusion that extends over the wall and the photodiodes of the first and second sets of photodiodes; and

one or more processors configured to;

receive information responsive to at least one of the first signal stream or the second signal stream; and

process the information to determine physiological parameter measurement information.

17. The noninvasive physiological parameter measurement device of claim 15, wherein the first and second sets of photodiodes are arranged on a substrate, and wherein the protrusion extends over at least a part of the substrate.

18. The noninvasive physiological parameter measurement device of claim 17 further comprising preprocessing electronics including at least:

first preprocessing electronics configured to preprocess the first signal stream; and

second preprocessing electronics configured to preprocess the second signal stream,

wherein the information responsive to the at least one of the first signal stream or the second signal stream is received by the one or more processors after preprocessing of the at least one of the first signal stream or the second signal stream.

19. The noninvasive physiological parameter measurement device of claim 18, wherein:

the first preprocessing electronics comprise at least a first amplifier configured to receive the first signal stream and at least amplify the first signal stream, and

the second preprocessing electronics comprise at least a second amplifier configured to receive the second signal stream and at least amplify the second signal stream.

20. The noninvasive physiological parameter measurement device of claim 19, wherein the preprocessing further comprises converting at least one of the first signal stream or the second signal stream from analog to digital.

22. The noninvasive physiological parameter measurement device of claim 19, wherein the protrusion comprises a convex protrusion, and wherein at least a portion the convex protrusion is comprised of a sufficiently rigid material to cause tissue of a wearer of the noninvasive physiological parameter measurement device to conform to at least a portion of a shape of the convex protrusion when the noninvasive physiological parameter measurement device is worn by the wearer.

23. The noninvasive physiological parameter measurement device of claim 22, wherein the physiological parameter comprises at least one of:

pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.

24. The noninvasive physiological parameter measurement device of claim 23, wherein at least part of the protrusion is light permeable.

25. The noninvasive physiological parameter measurement device of claim 23 further comprising:

one or more openings that allow light to pass through to the photodiodes of the first and second sets of photodiodes.

26. The noninvasive physiological parameter measurement device of claim 25 further comprising:

a strap configured to facilitate attachment of at least part of the noninvasive physiological parameter measurement device to an arm of the wearer; and

a touch-screen display,

wherein the one or more processors are further configured to cause communication of the physiological parameter measurement information to a user interface displayed on the touch-screen display.

27. The noninvasive physiological parameter measurement device of claim 26, wherein the attenuated light is reflected by the tissue.

28. The noninvasive physiological parameter measurement device of claim 27, wherein the one or more processors are further configured to:

cause transmission of the physiological parameter measurement information to at least one of;

a mobile phone, or a computer network.

29. A physiological measurement system comprising:

a noninvasive physiological parameter measurement device according to claim 28; and

a mobile phone configured to wirelessly communicate with the noninvasive physiological parameter measurement device.

16. (canceled)

21. (canceled)

30. A noninvasive physiological parameter measurement device adapted to be worn by a wearer, the noninvasive physiological parameter measurement device comprising:

one or more light emitters;

a substrate having a surface;

a first set of photodiodes arranged on the surface and spaced apart from each other, wherein;

the first set of photodiodes comprises at least four photodiodes, and

the photodiodes of the first set of photodiodes are connected to one another in parallel to provide a first signal stream responsive to light from at least one of the one or more light emitters attenuated by body tissue;

a second set of photodiodes arranged on the surface and spaced apart from each other, wherein;

the second set of photodiodes comprises at least four photodiodes,

the photodiodes of the second set of photodiodes are connected to one another in parallel to provide a second signal stream responsive to light from at least one of the one or more light emitters attenuated by body tissue,

at least one of the first signal stream or the second signal stream includes information usable to determine a physiological parameter of a wearer of the noninvasive physiological parameter measurement device, and

the physiological parameter comprises at least one of;

pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide;

first preprocessing electronics configured to preprocess the first signal stream, the first preprocessing electronics comprising at least a first amplifier configured to receive the first signal stream and at least amplify the first signal stream;

second preprocessing electronics configured to preprocess the second signal stream, the second preprocessing electronics comprising at least a second amplifier configured to receive the second signal stream and at least amplify the second signal stream;

a wall extending from the surface and configured to surround at least the first and second sets of photodiodes;

a cover arranged to cover at least a portion of the surface of the substrate, wherein;

the cover comprises a protrusion that extends over all of the photodiodes of the first and second sets of photodiodes arranged on the surface,

the protrusion comprises a convex protrusion,

at least a portion the cover is comprised of a sufficiently rigid material to cause tissue of the wearer to conform to at least a portion of a shape of the cover,

the cover is further configured to cover the wall, and

the wall operably connects to the substrate on one side and operably connects to the cover on an opposite side;

one or more openings that allow light to pass through to the photodiodes of the first and second sets of photodiodes;

a touch-screen display;

a strap configured to facilitate attachment of at least part of the noninvasive physiological parameter measurement device to an arm of the wearer; and

one or more processors configured to;

receive information responsive to at least one of the first signal stream or the second signal stream;

process the information to determine physiological parameter measurement information;

cause communication of the physiological parameter measurement information to a user interface displayed on the touch-screen display; and

cause transmission of the physiological parameter measurement information to at least one of;

a mobile phone, or a computer network.