Antibiotics tylosin and desmycosin and derivatives thereof
First Claim
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6. A COMPOUND SELECTED FROM THE GROUP CONSISTING OF TYLOSIN, DESMYCOSIN, AND ACID ADDITION SALTS THEREOF, SAID TYLOSIN BEING CHARACTERIZED AS A WHITE, SOLID SUBSTANCE, SOLUBLE IN ACIDIC AQUEOUS SOLUTION AND IN MOST POLAR SOLVENTS, BEING SUBSTANTIALLY INSOLUBLE IN MOST POLAR ORGANIC SOLVENTS AND IN ALKALINE AQUEOUS SOLUTIONS, BEING STABLE IN AQUEOUS SOLUTION AT A PH IN THE RANGE OF ABOUT PH 4 TO ABOUT PH 9, HAVING A MOLECULAR WEIGHT OF ABOUT 900, HAVING SHOWN UPON ANALYSIS THE PRESENCE OF 59.68 PERCENT CARBON, 8.53 PERCENT HYDROGEN, 1.55 PERCENT NITROGEN, AND BY DIFFERENCE 30.24 PERCENT OXYGEN, THE SAID ANALYTICAL VALUES ESTABLISHING THE EMPIRICAL FORMULA
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6 Claims
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6. A COMPOUND SELECTED FROM THE GROUP CONSISTING OF TYLOSIN, DESMYCOSIN, AND ACID ADDITION SALTS THEREOF, SAID TYLOSIN BEING CHARACTERIZED AS A WHITE, SOLID SUBSTANCE, SOLUBLE IN ACIDIC AQUEOUS SOLUTION AND IN MOST POLAR SOLVENTS, BEING SUBSTANTIALLY INSOLUBLE IN MOST POLAR ORGANIC SOLVENTS AND IN ALKALINE AQUEOUS SOLUTIONS, BEING STABLE IN AQUEOUS SOLUTION AT A PH IN THE RANGE OF ABOUT PH 4 TO ABOUT PH 9, HAVING A MOLECULAR WEIGHT OF ABOUT 900, HAVING SHOWN UPON ANALYSIS THE PRESENCE OF 59.68 PERCENT CARBON, 8.53 PERCENT HYDROGEN, 1.55 PERCENT NITROGEN, AND BY DIFFERENCE 30.24 PERCENT OXYGEN, THE SAID ANALYTICAL VALUES ESTABLISHING THE EMPIRICAL FORMULA
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Current AssigneeJames M. Mcguire, Martha C. Stamper, Michael E. Haney Jr, Robert L. Hamill
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Original AssigneeJames M. Mcguire, Martha C. Stamper, Michael E. Haney Jr, Robert L. Hamill
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InventorsHamill, Robert L., Haney, Michael E. Jr., Mcguire, James M., Stamper, Martha C.
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Application NumberUS04/039,104Time in Patent Office1,751 DaysField of SearchUS Class Current424/120CPC Class CodesA23K 20/195 AntibioticsY10S 435/896 Streptomyces fradiae
