DRESSING

• US 3,814,097 A
• Filed: 01/24/1973
• Issued: 06/04/1974
• Est. Priority Date: 02/14/1972
• Status: Expired due to Term

• Current Assignee: David Ganderton, Gordon Varney, James Mcainsh
• Original Assignee: David Ganderton, Gordon Varney, James Mcainsh
• Inventors: McAinsh, James, Ganderton, David, Varney, Gordon
• Primary Examiner(s): Medbery, Aldrich F.
• Application Number:
  US05/326,474
• Time in Patent Office: 496 Days
• Field of Search: 128/2W,260,268,253,215,333,214F
• US Class Current: 604/304
• CPC Class Codes: A61F 13/00063 comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic drug delivery dressings A61K9/70; chemical aspect of the additives A61L15/00
• CPC Class Codes: A61F 13/05 specially adapted for use with sub-pressure or over-pressure therapy, wound drainage or wound irrigation, e.g. for use with negative-pressure wound therapy [NPWT]
• CPC Class Codes: A61F 2013/0017 possibility of applying fluid
• CPC Class Codes: A61K 9/0021 Intradermal administration, e.g. through microneedle arrays, needleless injectors mechanical aspects A61M
• CPC Class Codes: A61M 2037/0007 having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles

Abstract

A dressing for administering a drug through the skin of a host comprising a reservoir for the drug and, located between the reservoir and the skin of the host when the dressing is in use, a pad provided with tiny spikes. These tiny spikes augment the absorption of the drug without causing irritation.

Claims

1. A pad for augmenting the absorption of a liquid formulation of a pharmacologically active material through the skin of a host comprising a sheet of material, a plurality of tiny hollow fibres passing through the sheet and projecting from at least one face of said sheet, said fibres having an external diameter at the end of the fibre in the range 8 Mu m. to 100 Mu m. and projecting from said sheet from 20 Mu m. to 1,000 Mu m and a means on one side of said sheet material constituting a means for supplying said liquid material.

2. A pad according to claim 1 wherein the sheet is provided with a multitude of said tiny hollow fibres.

3. A pad according to claim 1 wherein the fibres are composed of glass.

4. A pad according to claim 3 wherein the sheet is made from cellulose acetate.

5. A dressing for administering a liquid formulation of a pharmacologically active material to a host through the skin of said host, comprising a pad according to claim 1 said supply means comprising a reservoir for receiving a liquid formulation of the pharmacologically active material located to permit said liquid formulation, when present, to pass from said reservoir and through said pad to the skin of said host.

6. A dressing according to claim 5 wherein the reservoir comprises a case with the pad forming one wall.

7. A dressing according to claim 5 which additionally includes pressure applying means for increasing the pressure in the reservoir.

8. A dressing according to claim 5 which additionally includes securing means for attaching the dressing to the skin of the host.

9. A dressing according to claim 5 wherein the reservoir contains a plug for the insertion of a means for supplying said liquid formulation of the pharmacologically active material.

10. A dressing according to claim 9 wherein the pharmacologically active material is a polypeptide.