Intravascular liquid velocity sensing method using a polarographic electrode
First Claim
1. The method of measuring the flow rate of an intravascular aqueous liquid containing dissolved oxygen comprising contacting said liquid with a polarographic cathode having a surface area greater than 8 square millimeters and with a reference anode, applying between said cathode and said anode a fixed, predetermined d.c. voltage corresponding to the characteristic plateau current of said liquid, said voltage being in the order of 0.4-0.9 volts and, while maintaining said predetermined voltage, measuring the current passing between said anode and said cathode, said current being variable as a function of the rate of flow of said liquid over a substantial range due to the substantial electrode area available to produce depletion in the adjacent volume of said liquid.
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Abstract
The linear flow rate of a liquid containing dissolved oxygen, such as blood, can be determined by means of an electrode assembly having exposed to the liquid a relatively large polarographically active cathode and spaced therefrom a reference anode. With an applied energizing voltage of about 0.4-0.9 volts a current plateau is reached which is proportional to fluid flow rate. As the device is also sensitive to oxygen content, compensation can be measured by providing on the assembly an oxygen sensing membrane covered polarographic electrode pair of the Clark type.
117 Citations
1 Claim
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1. The method of measuring the flow rate of an intravascular aqueous liquid containing dissolved oxygen comprising contacting said liquid with a polarographic cathode having a surface area greater than 8 square millimeters and with a reference anode, applying between said cathode and said anode a fixed, predetermined d.c. voltage corresponding to the characteristic plateau current of said liquid, said voltage being in the order of 0.4-0.9 volts and, while maintaining said predetermined voltage, measuring the current passing between said anode and said cathode, said current being variable as a function of the rate of flow of said liquid over a substantial range due to the substantial electrode area available to produce depletion in the adjacent volume of said liquid.
Specification
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- Resources
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Current AssigneeCordis Corporation (Cardinal Health, Inc.)
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Original AssigneeCordis Corporation (Cardinal Health, Inc.)
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InventorsWilliamson, Donald E.
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Primary Examiner(s)Gaudet, Richard A.
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Assistant Examiner(s)Cohen, Lee S.
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Application NumberUS05/512,477Time in Patent Office456 DaysField of Search128/2.05 F, 128/2 L, 128/2 E, 128/2.1 E, 128/2.05 D, 73/194 F, 73/194 E, 324/29 R, 324/30 R, 204/195 B, 204/195 P, 204/195 R, 204/195 L, 204/195 MUS Class Current600/505CPC Class CodesA61B 5/027 using cathetersA61B 5/14542 for measuring blood gases A...A61B 5/1473 invasive, e.g. introduced i...
