Reflection standard for fiber optic probe

• US 4,050,450 A
• Filed: 03/05/1976
• Issued: 09/27/1977
• Est. Priority Date: 03/05/1976
• Status: Expired due to Term

• Current Assignee: Warner-Lambert Company (Pfizer Inc.)
• Original Assignee: American Optical Corporation
• Inventors: Ostrowski, David Stanley, Polanyi, Michael Lajos
• Primary Examiner(s): Howell, Kyle L.
• Application Number:
  US05/664,345
• Time in Patent Office: 571 Days
• Field of Search: 128/2 L, 128/2 M, 128/9, 128/214 R, 356/39-41
• US Class Current: 600/332
• CPC Class Codes: A61B 2560/0233 Optical standards
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: G01N 21/474 Details of optical heads therefor, e.g. using optical fibres

Abstract

A flexible fiber optic probe or catheter insertable into the cardiovasular system for monitoring blood oxygen saturation or the like is provided with an improved standard for the calibration of the catheter and its associated electro-optic equipment. The improved calibration standard is particularly suited for catheters of very small diameter, is provided by a generally tubular reflecting member aligned with and adjacent to the distal end of the catheter. The reflecting member may be vinyl tubing or the like which may be removably of fixedly positioned about the distal end of the catheter to reflect light directed thereon from the catheter when in air or a clear sterile solution for calibration.

Claims

1. In a fiber optic probe for use in measuring amounts of diffuse reflection of light from a target medium, said probe having light conducting fiber means and a housing tubing surrounding said light conducting fiber means, said light conducting fiber means extending between the proximal and distal ends of the housing tubing with the corresponding end faces thereof exposed at said proximal and said distal ends of the probe respectively, the improvement comprising:

reflecting means for establishing a calibration standard, said reflecting means having a generally tubular passage therein defining an interior surface, said tubular passage having a diameter at least as great as said light conducting fiber means, said reflecting means extending distally from the end face of said light conducting fiber means at the distal end of the housing tubing with said passage in registry with said light conducting fiber means, at least said interior surface of said reflecting means being a material which characteristically diffusely reflects and returns a fixed ratio of at least two preselected wavelengths of light directed thereupon from said exposed face of said light conducting fiber means at said distal end of said probe when said distal end exposed face of said fiber means and said reflecting means is disposed in air and clear fluids, said returned fixed ratio of light providing a calibration standard.

2. The fiber optic probe of claim 1 wherein said reflecting means extends distally from said end face at least a minimum length greater than which said fixed ratio of said at least two preselected wavelengths of returned light is substantially constant.

3. The fiber optic probe of claim 2 wherein said minimum extension length of said reflecting means is about at least twenty times the diameter of said housing tubing.

4. The fiber optic probe of claim 2 wherein said reflecting means removably embraces the housing of said optic probe.

5. The fiber optic probe of claim 4 wherein said probe is a catheter and said target medium is blood, said distal end of the catheter being disposed in said blood for said measurement of diffuse reflection of light therefrom and said reflecting means being removed from said catheter prior to said measurement in blood.

6. The fiber optic probe of claim 5 wherein said reflecting means and said interior surface thereof comprise a white pigmented plastic material.

7. The fiber optic probe of claim 5 wherein said tubular passage extends through said reflecting means.

8. The fiber optic probe of claim 1 wherein said probe is a catheter, said target medium is blood and said reflecting means is in fixed engagement with the housing of said probe.

9. The fiber optic probe of claim 8 wherein said reflecting means includes port means extending transversely therethrough adjacent the end face of said optical fiber means at the distal end of said probe for allowing blood to flow by said optical fiber means end face.

10. The fiber optic probe of claim 8 wherein said catheter is intended for use in measuring amounts of diffuse reflection of light from blood within the cardiovascular system of a living subject, said reflecting means being sufficiently rigid to prevent its collapse by contact with the cardiovascular walls to an extent which would occlude the end face of said light conducting fiber means at the distal end of said housing tubing and being sufficiently flexible to facilitate its passage within the cardiovascular system.

11. The fiber optic probe of claim 1 wherein said reflecting means and said interior surface thereof comprises a white pigmented plastic material.

12. The fiber optic probe of claim 1 wherein said light conducting fiber means comprises a multiplicity of light conducting fibers all being intimately juxtaposed adjacent said distal end of the probe, and the diameter of said passage and the positioning of said reflecting means place said passage in registry with said multiplicity of light conducting fibers.

13. The fiber optic probe of claim 1 wherein the diameter of said passage in said reflecting means is at least as great as the exterior diameter of said probe housing tubing and said reflecting means additionally extends rearwardly of said distal end of the probe in encircling relationship therewith.

14. In a fiber optic catheter for use in measuring amounts of diffuse reflection of light in blood, said catheter having light-conducting fiber means and a catheter tubing surrounding said fiber means, said fiber means extending between the proximal and distal ends of the catheter tubing with corresponding end faces thereof exposed at said proximal and distal ends of the catheter respectively, a reflecting member cooperatively associated with said catheter adjacent the distal end thereof serving to characteristically diffusely reflect and return a fixed ratio of at least two preselected wavelengths of light directed thereupon from said exposed face of said light-conducting fiber means at said distal end of said catheter when said distal end exposed face of said fiber means and said reflecting member are disposed in air and clear fluids for establishing a calibration standard, the improvement wherein said reflecting member comprises a tube of white pigmented plastic material, said tube having a proximal portion in concentric removable embracing relationship with said distal end of said catheter tubing and a distal portion extending distally beyond said distal end of said catheter, said tube distal portion having an interior surface of said white plastic material for said diffuse reflection of said two preselected wavelengths of light.

15. The method of calibrating and using a fiber optic probe to measure amounts of diffuse reflection of light from blood, said probe having light conducting fiber means in a housing tubing surrounding said light conducting fiber means, said light conducting fiber means extending between the proximal and distal ends of the housing tubing with the corresponding end faces thereof exposed at said proximal and said distal ends of the probe respectively, comprising the steps of:

positioning a reflecting means having a generally tubular passage therein adjacent to said light conducting fiber means at the distal end of said housing tubing, said tubular passage having a diameter at least as great as said light conducting fiber means and being in optical registry therewith, said tubular passage defining an interior surface in said reflecting means, said interior surface being of a material which characteristically diffusely reflects and returns a fixed ratio of at least two preselected wavelengths of light directed thereupon from said exposed face of said light conducting fiber means at said distal end of said probe when said distal end exposed face of said fiber means and said reflecting means is disposed in air and clear fluids, said returned fixed ratio of light providing a calibration standard;

disposing said distal end exposed face of said fiber means and said reflecting means adjacent thereto in air or a clear fluid to establish said calibration standard; and

subsequently disposing at least said exposed face of said light conducting fibers in blood for measuring the diffuse reflection of light from the blood.

16. The method of claim 15 further including the step of removing said reflecting means from said position adjacent said distal end exposed face of said fiber means following said disposing in air or clear fluid to establish said calibration standard and prior to said disposing in blood for measuring said amounts of diffuse reflection of light from the blood.

17. The method of claim 15 wherein said reflecting means comprises flexible tubing which remains affixed to said housing tubing during said disposing in blood for measuring said amounts of diffuse reflection of light from the blood.