Toothpaste permitting of controlling the tooth brushing time

• US 4,150,106 A
• Filed: 04/12/1978
• Issued: 04/17/1979
• Est. Priority Date: 02/16/1978
• Status: Expired due to Term

• Current Assignee: Bernard Blanc
• Original Assignee: The Cooper Companies Incorporated
• Inventors: Assal, Jacques, Monnerat, Bernard, Blanc, Bernard
• Primary Examiner(s): Rose, Shep K.
• Application Number:
  US05/895,612
• Time in Patent Office: 370 Days
• Field of Search: 424/7, 424/49-58
• US Class Current: 424/9.7
• CPC Class Codes: A61K 2800/45 Colour indicators, e.g. pH- or Redox indicators
• CPC Class Codes: A61K 8/49 containing heterocyclic compounds
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

This toothpaste contains reagents for controlling the tooth brushing time by the change in color occurring after a predetermined brushing time. It contains essentially a citrate/citric acid buffer having a molarity of 0.07 to 0.35 M and a pH of 4 to 5.5 in the proportion of 10 to 50%, and chlorophenol red in the proportion of 0.02 to 0.1%.

Claims

1. A toothpaste containing reagents for controlling the tooth brushing time by the change in color occurring after a predetermining brushing time, said reagents comprising essentially a citrate-citric acid buffer having a molarity within the range of 0.07 to 0.35 M with a pH of 4 to 5.5 in the proportion of 10 to 50% and chlorophenol red in the proportion of 0.02 to 0.1%.

2. A toothpaste according to claim 1, having the following composition:

a mixture, not in excess of 3.5% of synthetic polymers carboxypolymethylenes) and modified celluloses (sodium carragheenate);

8 to 25% silicic acid;

1 to 6% silica;

1.5 to 3% Sodium dodecylhydrogensulphate;

3 to 4 propandiol;

20 to 60% sorbitol;

0.1 to 0.5% p-hydroxybenzoic acid esters;

0.02 to 0.1% chlorophenol red;

about 1.5% aromas;

0.01 to 0.04% foodstuff dyes;

10 to 50% of a citrate/citric acid buffer having a ionic strength and a pH value adapted to yield a final pH within the range of 4.0 to 5.5;

water, q.s 100%.

3. Toothpaste according to claim 2, wherein the carboxypolymethylene and carragheenate consist of Carbopol 940 and Satiagum B.

4. A toothpaste according to claim 2, wherein said esters of p-hydroxybenzoic acid are a mixture of methyl p-hydroxybenzoate and popyl p-hydroxybenzoate.

5. A toothpaste according to claim 2, wherein said citrate buffer consists of 0.07 M citric acid and 0.07 M sodium citrate set at a pH of 4.2 to 4.6.

6. Toothpaste according to claim 2, wherein said foodstuff dye is a moderately concentrated corn-poppy red (0.01 to 0.04%) in order not to interfere with the turning of the chlorophenol red to purple red.

7. Toothpaste according to claim 1, of which the preferred composition is:

space="preserve" listing-type="tabular">______________________________________ Carbopol 940 1.5% Satiagum B 1.5% Silicic acid 10.0% Titanium dioxide 4.0% Sodium laurylsulphate 2.1% 70% Sorbitol 33.0% Methyl p-hydroxybenzoate 0.15% Propyl p-hydroxybenzoate 0.15% Chlorophenol red 0.05% Aromas 1.3% Sodium Saccharin 0.5% Sodium monofluorophosphate 0.75% Bromochlorophene 0.15% Buffer ;

0.07 M citric acid/ sodium citrate, pH = 4.5 q.s. 100.00 grams. ______________________________________