Method and apparatus for detecting a blood leak in a hemodialysis system

• US 4,166,961 A
• Filed: 03/22/1978
• Issued: 09/04/1979
• Est. Priority Date: 03/22/1978
• Status: Expired due to Term

• Current Assignee: Hoechst Aktiengesellschaft (Sanofi )
• Original Assignee: Hoechst Aktiengesellschaft (Sanofi )
• Inventors: Hufnagel, John P., Dam, Naim G.
• Primary Examiner(s): Nelms, David C.
• Application Number:
  US05/888,859
• Time in Patent Office: 531 Days
• Field of Search: 210/22 A, 210/22 C, 210/321, 250/573, 250/574, 250/575, 250/214 R, 356/39
• US Class Current: 250/573
• CPC Class Codes: A61M 1/1692 Detection of blood traces in dialysate
• CPC Class Codes: B01D 65/104 Detection of leaks in membrane apparatus or modules
• CPC Class Codes: G01F 1/661 using light
• CPC Class Codes: G01M 3/38 by using light G01M3/02 takes precedence

Abstract

A blood leak in the dialyzer is detected by transmitting a pulsed beam of light into the dialysate flowstream at a predetermined angle of incidence between the central axis of the flowstream and the normal axis and measuring variations in reflecting light received by a photodetector arranged on the same side of the flowstream as the phototransmitter at a predetermined angle of reflection. The beam of light is interupted at a rate with a substantially equal on-time to off time ratio.

Claims

1. A method for detecting the presence of blood in the dialysate flowstream of a hemodialysis system comprising the steps of:

transmitting a narrow beam of light into said dialysate flowstream from one side thereof in a direction incident upon the central axis of the flowstream with a predetermined angle of incidence relative to an axis normal to said central axis;

locating an optical receiver in a substantially common plane with said narrow beam of light and on the same side of said flowstream such that it forms an included angle of reflection with said normal axis substantially equal to said angle of incidence;

interrupting said transmission of light at a relatively low repetition rate with the ratio of on time to off time being substantially equal;

detecting the average DC level of the signal received by said optical receiver; and

generating an alarm signal when said average DC level exceeds a predetermined level.

2. A method as defined in claim 1 wherein said predetermined angle of incidence is substantially about 55°

.

3. A method as defined in claim 2 further comprising the steps of:

substracting a predetermined DC offset voltage from said average DC level;

converting the substracted signal into a digital signal;

storing said digital signal as a digital reference signal at the end of a first predetermined time;

repeatedly comparing said digital reference signal to said digital signal following said first predetermined time; and

generating said alarm signal when said digital signal varies from digital reference.

4. A method as defined in claim 3 wherein said repetition rate for interrupting said transmission of light is above zero and below about 100 H_z.

5. A method as defined in claim 4 wherein said narrow beam of light has a beam divergence of no more than about 12°

.

6. A sensor system for detecting the presence of blood in a conduit through which a dialysate solution flows for performing artificial kidney hemodialysis comprising:

an optical transmitter connected on one side of said conduit for transmitting a narrow beam of light into said dialysate solution at a predetermined angle of incidence relative to an axis normal to said central axis;

an optical receiver connected to said conduit on the same side thereof as said transmitter in substantially the same plane and at a predetermined angle of reflection relative to said normal axis for receiving reflected light from said dialysate solution, said angle of reflection being substantially equal to said predetermined angle of incidence;

means for intermittently passing pulses of direct current through said optical transmitter at a relatively low frequency with a pulse width being at least substantially equal in duration to the time separation between pulses;

means for detecting the output of said optical receiver;

means for generating an output DC signal responsive to the average DC level of said detected output; and

means responsive to said output DC signal for providing an output alarm signal when said output DC signal exceeds a predetermined level.

7. A system as defined in claim 6 wherein said predetermined angle of incidence is substantially about 55°

.

8. A system as defined in claim 7 wherein said means for intermittently passing pulses of direct current through said optical transmitter comprises an oscillator and means for generating a constant current during a predetermined portion of each oscillating cycle.

9. A system as defined in claim 8 wherein said means for generating a DC output signal comprises a peak envelop detector.

10. A system as defined in claim 9 wherein said means for providing an output alarm signal comprises:

a difference amplifier having one input connected to said output DC signal and a second input connected to the output of an adjustable DC reference source,

means for converting the output of said difference amplifier into a digital control signal; and

microcomputer means for tracking said digital control signal for a first predetermined period of time, storing said digital control signal as a digital reference signal at the end of said first period of time and comparing said digital reference signal to said digital control signal following said first predetermined period of time.