Apparatus for measurement of expired gas concentration in infants

• US 4,202,352 A
• Filed: 04/06/1978
• Issued: 05/13/1980
• Est. Priority Date: 04/06/1978
• Status: Expired due to Term

• Current Assignee: Johnson & Johnson Medical Incorporated (Johnson & Johnson)
• Original Assignee: UAB Research Foundation (University of Alabama System)
• Inventors: Osborn, John J.
• Primary Examiner(s): Howell, Kyle L.
• Application Number:
  US05/894,170
• Time in Patent Office: 768 Days
• Field of Search: 128/2.07, 128/2.08, 128/2 C, 128/719, 128/727, 128/728, 128/730, 73/123 R, 73/421.5 R
• US Class Current: 600/532
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: G01N 33/497 of gaseous biological material, e.g. breath

Abstract

Apparatus for measuring expired gas concentration in infants whose breathing rate is too high for normal analyzers by sampling the breath, for instance from the tube between the respirator and the infant, and drawing that sample of gas into an elongated, small diameter tube which serves to store the sample in a linear array substantially without intermixing. Several breaths are thus stored after which time the sampling may be interrupted and the stored gas drawn slowly through a gas analyzer.

Claims

1. In an apparatus for measuring expired gas concentrations of a patient, an airway adapted to be placed in communication with the patient'"'"'s respiratory system, pump means having its intake connected to said airway for drawing a predetermined volume of gas therefrom to be sampled, a captive bag assembly having an outer chamber and a captive bag within said outer chamber, the interior of said captive bag defining an inner chamber, the exhause of said pump means being connected to one of said chambers and the other of said chambers being connected to said airway whereby the captive bag assembly replenishes the gas to the airway in the same predetermined volume and simultaneously with the operation of said pump means to draw gas therefrom.

2. Apparatus as defined in claim 1 wherein said airway includes first and second taps, the intake of said pump means being connected to said first tap, said one of said chambers being connected to said second tap, and baffle means disposed in said airway between said taps for isolating the same.

3. Apparatus as defined in claim 1 wherein said airway includes an elongated tube having an internal diameter sufficiently small in consideration of pumping capacity of said pump means to provide laminar flow therethrough and a length sufficiently great, compared to the lung volume and respiration rate of the patient, that the transit time of a gas particle through the tube is greater than the time required for several breaths of the patient.

4. Apparatus as defined in claim 3 wherein said elongated tube has an internal diameter no greater than 1 mm. and a length of approximately 10 meters, said pump means having a pumping capacity of about 0.5 liter per minute.

5. In an apparatus for measuring expired gas concentrations of an infant, an airway adapted to be placed in communication with the infant'"'"'s respiratory system, an elongated tube, pump means in communication with said elongated tube for pumping respiratory gas therethrough, a gas analyzer, valve means having a first position placing said elongated tube in communication with said airway whereby gases from the respiratory system of the infant may be drawn into said elongated tube by said pump means, said valve means having a second position placing said elongated tube in communication with said gas analyzer whereby gases previously drawn into said elongated tube while the valve means was in its first position may be analyzed when said valve means is in its second position.

6. Apparatus as defined in claim 5 wherein said elongated tube has an internal diameter sufficiently small in consideration of the pumping capacity of said pump means to provide laminar flow therethrough and a length sufficiently grea, compared to the lung volume and respiration rate of the infant, that the transit time of gas particle through the tube is greater than the time required for several breaths of the infant.

7. Apparatus as defined in claim 6 wherein said elongated tube has an internal diameter no greater than 1 mm. and a length of approximately 10 meters, and pump means having a capacity of about 0.5 liter per minute.

8. Apparatus as defined in claim 5 wherein said pump means includes means for drawing a predetermined volume of gas from said airway through elongated tube when said valve means is in its first position, together with replenish means coupled to said airway for replenishing gas therein in the same predetermined volume and at the time said valve means is in its first position.

9. Apparatus as defined in claim 8 wherein said replenish means comprises a captive bag assembly having an outer chamber and a captive bag within said outer chamber, the interior of said captive bag defining an inner chamber, one of said chambers being in communication with said airway and the other of said chambers being in communication with said elongated tube when said valve means is in its first position.

10. Apparatus for measuring expired gas concentrations of a patient comprising pumping means adapted to be placed in communication with the airway of the patient for drawing a sample of the patient'"'"'s respiratory gases, storage means in communication with said pumping means for storing the drawn respiratory gases in a sequence corresponding to the sequence that the gases are expired by the patient, a gas analyzer for analyzing said gases and valve means for interrupting the communication between said storage means and the airway of the patient and for simultaneously placing said storage means in communication with said gas analyzer.