Allergy testing device with vented base

• US 4,222,392 A
• Filed: 05/23/1979
• Issued: 09/16/1980
• Est. Priority Date: 05/23/1979
• Status: Expired due to Term

• Current Assignee: Krueger JANE 30% & Brennan Louis G 70% Brennan Cynthia B 70% Both Jointly A Seventy Percent Undivided Interest
• Original Assignee: Alier-Screen Incorporated
• Inventors: Brennan, Louis G.
• Primary Examiner(s): Howell, Kyle L.
• Application Number:
  US06/041,957
• Time in Patent Office: 482 Days
• Field of Search: 128/743, 128/253, 206/364, 206/439
• US Class Current: 600/556
• CPC Class Codes: A61B 10/00 Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis vaccination prophylaxis, vaccination therapy A61B17/20; Sex determination; Ovulation-period determination menstruation tables G06C3/00; Throat striking implements

Abstract

An improved skin test kit comprising base well means and a plurality of injection units held in recessed depressions of the base and removable therefrom is provided with vent means for permitting gas escape during insertion of the injection units. The injection units comprise a hilt portion which may be mated with the periphery of the well depression. A vent hole communicating with a portion of the depression can vent gas through the base bottom, thereby preventing excessive pressure in the well means. The injection unit includes a hollow cannula within a hollow handle with a sharp point extending into liquid test substance in its respective well. Each cannula can be loaded with a predetermined amount of liquid by capillary action and the vent means prevents overloading and provides a controlled amount of liquid to be held in the cannula elements.

Claims

1. An improved allergy testing kit for allergen screening comprising:

a base member comprising a plurality of recessed depressions each having a well portion adapted to receive a needle-like prong, each of said depressions having annular ridge means disposed within said depression surrounding said well portion;

a plurality of intracutaneous injection units held in the recessed depressions of said base member and individually removable therefrom, each of said injection units comprising a hilt portion adapted for insertion into the recessed depression of said base member, an upwardly extending handle portion and a downwardly extending skin test prong portion adapted for insertion into a corresponding well, wherein each prong comprises a hollow metal cannula extending from the hilt into the corresponding well, and wherein the handle portion of each injection unit is hollow to receive an upper portion of said cannula, thereby permitting capillary loading of the prongs by dipping the prong into a liquid;

at least one of said prongs being loaded with biologically active allergen;

at least one of said prongs being loaded with a histamine control substance;

at least one of said prongs being loaded with a diluent devoid of biologically active substance; and

vent means for permitting gas escape during insertion of said injection units into said depressions.

2. The testing kit of claim 1 wherein said vent means comprises at least one hole communicating with that portion of said depression outside said annular ridge means for venting gas through a bottom portion of said base.

3. The testing kit of claim 1 wherein said hilt portions and said recessed depressions are closely mated, thereby forming a seal and resiliently holding said injection units.

5. The testing kit of claim 1 wherein said allergen is provided in a concentration of about 50 to 100 grams per liter.

6. The testing kit of claim 1 wherein at least one biologically active allergen substance comprises a mixture of allergens.

13. The testing kit of claim 1 wherein said well portion and annular ridge means are substantially circular and concentric with a circular periphery of said depression, and wherein said vent means comprises a vent hole in said base between said ridge means and said periphery.

4. The testing kit of claim wherein said hilt portion comprises a two-tier configuration with a small central tier portion adjacent said cannula and a large tier portion adjacent said handle portion.

7. In a skin test kit for in vivo intracutaneous use including a base member having a plurality of base well means for holding liquid test substances and having depressions for receiving and holding a corresponding plurality of injection units in cooperation with lid means, each of said injection units comprising a plate portion closely mated with a peripheral area of said base well means for sealing the liquid test substances, a hollow open-top handle portion attached to the plate portion on one side thereof and adapted for manually grasping the device, and a hollow cannula element mounted on said plate and extending outwardly from said plate opposite said handle portion a predetermined length for intracutaenous injection, said cannula having a sharp skin-piercing point at its lower extremity and an upper shaft portion extending upwardly through said plate into said hollow handle portion;

whereby said device may be loaded with a predetermined amount of fluent skin testing substance applied to said point by dipping and distributed into the cannula by capillary action;

the improvement which comprises fluid control means comprising at least one hole communicating with said base will means forequalizing pressure in said well means and providing a controlled amount of liquid test substance to be held in the hollow cannula element of said injection units.

8. The skin test kit of claim 7 wherein said plate portion includes a two-tier configuration having a small central hilt portion adjacent said cannula and larger outer plate portion recessed from said inner hilt portion, thereby disguising puncture of said cannula into and providing standardized skin penetration.

9. The skin test kit of claim 7 comprising at least one injection unit loaded with an effective amount of admixed allergens selected from tree allergens, mold allergens,grass allergens, ragweed allergens, epidermals, dust and weed allergens;

and further comprising histamine control substance and diluent control substance.

10. The skin test kit of claim 7 which comprises annular ridge means disposed within said depression and wherein said pressure equalization means comprises at least one vent hole in said base means between said ridge means and the periphery of said depression.

11. The skin test kit of claim 7 wherein said fluid control means comprises a hole in said plate portion of said injection unit.

12. The skin test kit of claim 12 wherein said plate portion and said depression are closely mated, thereby forming a seal and resiliently holding said injection unit.