Transdermal delivery of drugs
First Claim
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1. An improved medical bandage for the administration of drug through the skin or mucosa which comprises a layered bandage comprising first a heat-generating layer containing a hydrate-forming inorganic salt dispersed throughout an inactive matrix layer, and second, a pressure-sensitive adhesive area containing drug to be administered to the patient, dispersed intimately throughout said adhesive layer.
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Abstract
An improved method for the topical administration of systemically or locally active drugs utilizes a bandage containing one or more layers including a drug useful in the treatment of disease and a heat-generating substance, each dispersed intimately throughout said bandage layers.
178 Citations
2 Claims
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1. An improved medical bandage for the administration of drug through the skin or mucosa which comprises a layered bandage comprising first a heat-generating layer containing a hydrate-forming inorganic salt dispersed throughout an inactive matrix layer, and second, a pressure-sensitive adhesive area containing drug to be administered to the patient, dispersed intimately throughout said adhesive layer.
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2. An improved medical bandage for the administration of drug through the skin or mucosa which comprises a layered bandage comprising first a heat-generating layer containing a heat-generating chemical substance dispersed throughout an inactive matrix layer, and second, a pressure-sensitive adhesive area containing drug to be administered to the patient, dispersed intimately throughout said adhesive layer.
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Current AssigneeMerck & Co., Inc.
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Original AssigneeMerck & Co., Inc.
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InventorsHarwood, Richard J.
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Primary Examiner(s)Rosenbaum, C. Fred
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Application NumberUS05/960,354Time in Patent Office715 DaysField of Search128/155-156, 128/260-261, 128/268, 128/293, 128/403US Class Current604/304CPC Class CodesA61K 9/703 characterised by shape or s...A61K 9/7053 obtained by reactions only ...B32B 2535/00 Medical equipment, e.g. ban...B32B 7/12 using interposed adhesives ...
