Self-locking cerebral electrical probe

• US 4,245,645 A
• Filed: 07/20/1978
• Issued: 01/20/1981
• Est. Priority Date: 09/28/1977
• Status: Expired due to Term

• Current Assignee: Gilles Tremblay, Gratien Bouillon, Pierre-Michel Arseneault, Roland Picard
• Original Assignee: Gilles Tremblay, Gratien Bouillon, Pierre-Michel Arseneault, Roland Picard
• Inventors: Tremblay, Gilles, Arseneault, Pierre-Michel, Picard, Roland, Bouillon, Gratien
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US05/926,391
• Time in Patent Office: 915 Days
• Field of Search: 128/642, 128/731, 128/784, 128/785, 128/786, 128/303 B
• US Class Current: 600/378
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/4094 Diagnosing or monitoring seizure diseases, e.g. epilepsy
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/6864 Burr holes
• CPC Class Codes: A61M 2025/006 having a special surface topography or special surface properties, e.g. roughened or knurled surface
• CPC Class Codes: A61M 2025/0213 where the catheter is attached by means specifically adapted to a part of the human body
• CPC Class Codes: A61M 2039/025 through bones or teeth, e.g. through the skull
• CPC Class Codes: A61M 2039/0261 Means for anchoring port to the body, or ports having a special shape or being made of a specific material to allow easy implantation/integration in the body
• CPC Class Codes: A61M 2039/0267 comprising sensors or electrical contacts
• CPC Class Codes: A61M 2210/02 Bones
• CPC Class Codes: A61M 2210/0693 Brain, cerebrum
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 25/02 Holding devices, e.g. on the body
• CPC Class Codes: A61M 25/06 Body-piercing guide needles or the like
• CPC Class Codes: A61M 39/0247 Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body peritoneal dialysis catheters A61M1/285; tracheostomy devices A61M16/0465; measuring pressure within the body A61B5/03; colostomy devices A61F5/445; gastrotomy feeding tubes A61J15/0015; means for fixing a feeding tube outside of the body A61J15/0053

Abstract

A self-locking encephalic electrical probe is used for stereoelectroencephalographic exploration in the treatment of epilepsy or other brain diseases. The probe includes a long, hollow, flexible tube of small diameter, preferably made of medium density polyethylene. A series of at least two electrically conductive rings, preferably made of silver, are located close to one another along the tube for detecting the electrical activity of nerve cells. A series of insulated electrical conductors are located inside the hollow tube, each conductor connecting a conductive ring to a multi-contact terminal located outside the hollow tube. A removable stylet is inserted into the hollow tube to give it rigidity and to control the direction of introduction of the probe into the brain. The stylet is removed from the tube to restore flexibility to the tube after the probe has been introduced in the brain. A self-locking rigid anchor preferably made of stainless steel holds the probe in place. The anchor is funnel-shaped and quickly and firmly fixes the hollow tube to the brain-pan of the patient after the probe has been introduced to the selected depth in the brain. The probe is used in conjunction with other probes for transmitting to a receptor the cerebral activity of the patient which is recorded and analyzed. As a result of this analysis, a medical staff may accurately locate the region of the brain that must be operated upon to cure the patient.

Claims

1. A probe for electroencephalographic exploration of a patient'"'"'s brain after being secured to the patient'"'"'s brain-pan, comprising:

a flexible tube of small diameter for insertion to a given depth in the brain of a patient;

at least two electrically conductive rings spaced along the flexible tube at relatively small distances from one another for detecting electrical activity of nerve cells in the brain;

a terminal block located outside the tube and having a plurality of terminals;

a plurality of insulated electrical conductors located inside the flexible tube, each conductor connecting one of the conductive rings to one of the terminals of the terminal block;

a removable stylet inserted inside the flexible tube for giving rigidity to the flexible tube and for enabling a directional insertion thereof into the brain whereby when the stylet is removed from the flexible tube after the tube has been inserted into the brain flexibility returns to the tube, the flexible tube and stylet each having one end for insertion into the patient'"'"'s brain and a free end opposite the one end; and

a self-locking, rigid anchor, the anchor including means for securing the anchor with respect to the brain-pan and means for quickly and firmly fixing the flexible tube to said anchor after the tube has been inserted to a given depth in the brain.

2. A probe as claimed in claim 1, wherein:

the flexible tube is made of medium density polyethylene and has an external diameter of substantially almost 1.5 mm;

the conductive rings are made of silver and comprise from five to ten elements spaced from each other at a constant interval of about 5 mm from the one end of the tube;

the removable stylet is made of stainless steel and is provided at its free end with a loop which is easy to seize so as to facilitate extraction of the one end of the stylet from the flexible tube when the probe has been introduced in the brain; and

the anchor is made of stainless steel and is in the shape of a small funnel through which the flexible tube is introduced.

3. The probe as claimed in claim 2, wherein the anchor comprises:

a first hollow section of cylindrical shape for insertion through the bone of the skull of the patient to the level of the internal tabula of the brain in order to provide an opening for the flexible tube and in order to guide the flexible tube;

a second hollow cylindrical section coaxial with and connected to the first section and having a diameter slightly larger than the diameter of the first section, the second section being for insertion through the muscle which covers the skull to provide an opening for the flexible tube;

a third section, coaxial with and connected to the second section wherein the third section is a hollow truncated cone having a curved and flared internal surface, the third section being for bearing against the skin of the patient and permitting the relatively easy introduction of the flexible tube into the first and second sections and subsequently into the brain; and

a fourth section of cylindrical shape attached to the third conical section, wherein the fourth section includes a lateral slot extending and opening longitudinally and two other slots registered with the lateral slot and extending partially around the fourth section, the slots selectively receiving and wedging the flexible tube in place once the stylet has been removed.

4. The probe as claimed in claim 3, wherein the terminals to which the conductors are connected are located outside of the flexible tube and are arranged side by side within the terminal block and wherein the terminal block is fixed to the free end of the tube so as to form a unit therewith.

5. The probe as claimed in claim 1, wherein the terminals to which the conductors are connected are located outside of the flexible tube and are arranged side by side within the terminal block and wherein the terminal block is fixed to the free end of the tube so as to form a unit therewith.

6. The probe as claimed in claim 1 further including a conductive tip disposed at the one end of the flexible tube, the conductive tip being connected to one of the electrical conductors.

7. A system for conducting an electroencephalographic exploration of a patient'"'"'s brain comprising a telemetric system, a telemetric receiver, and a probe coupled with said telemetric system so that information detected by the probe is transmitted by the telemetric system to the telemetric receiver, the telemetric receiver including means for decoding and recoding the transmitted information, the probe being for insertion into a patient'"'"'s brain and being for attachment to the patient'"'"'s brain-pan, the probe comprising:

a flexible tube of small diameter for insertion to a given depth in the brain of a patient;

at least two electrically conductive rings spaced along the flexible tube at relatively small distances from one another for detecting electrical activity of nerve cells in the brain;

a terminal block located outside the tube and having a plurality of terminals;

a plurality of insulated electrical conductors located inside the flexible tube, each conductor connecting one of the conductive rings to one of the terminals of the terminal block, the telemetric system being connected to the terminal block;

a removable stylet inserted inside the flexible tube for giving rigidity to the flexible tube and for enabling a directional insertion thereof into the brain, whereby, when the stylet is removed from the flexible tube after the tube has been inserted into the brain, flexibility returns to the tube; and

a self-locking, rigid anchor, the anchor including means for securing the anchor with respect to the brain pan and means for quickly and firmly fixing the flexible tube to said anchor after the tube has been inserted to a given depth in the brain.

8. A method of conducting an electroencephalographic exploration of a patient'"'"'s brain comprising the steps of:

(a) boring a hole through the patient'"'"'s scalp, scalp muscle and skull to the level of the tubula of the brain;

(b) inserting a hollow guide through the hole and anchoring the guide to the skull;

(c) inserting a flexible probe stiffened by a rigid stylet through the internal tubula and into the brain, said flexible probe being electrically sensitive through the hollow guide;

(d) restoring flexibility to the probe by withdrawing the rigid stylet from the probe;

(e) securing the probe to the guide; and

(f) monitoring electrical activity within the brain by detecting electrical signals with the probe.

9. The method of claim 8 further including the steps of:

repeating steps (a) through (f) at a plurality of locations on the patient'"'"'s head to obtain signals from various locations within the patient'"'"'s brain.

10. The method of claim 9 wherein step (f) includes detecting signals at different positions along the length of the probe to determine the depth within the brain at which the signals occur.

11. The method of claim 8 or 9 further including the step of:

obtaining stereoscopic radiographics of the patient'"'"'s brain prior to boring the holes to locate arteries and veins so that the arteries and veins may be avoided when inserting a probe.

12. The method of claim 8 wherein in step (f) monitoring is accomplished by transmitting radio signals from a transmitter connected to the probe and secured to the patient'"'"'s head at a location spaced from a remotely located receiver.

13. The method of claim 8 further including the step of monitoring the patient audio-visually while performing step (f) in order to correlate electrical brain activity with physiological behavior.

14. The method of claim 8 further including the step of inducing electrical activity in the brain by supplying electrical current to the probe from a source external to the brain.