Ostomy adhesive

• US 4,253,460 A
• Filed: 07/27/1979
• Issued: 03/03/1981
• Est. Priority Date: 07/27/1979
• Status: Expired due to Term

• Current Assignee: E R Squibb & Sons Incorporated
• Original Assignee: E R Squibb & Sons Incorporated
• Inventors: Chen, James L., Hill, John A., Cilento, Rudolfo D., La Via, Anthony L.
• Primary Examiner(s): Michell, Robert W.
• Assistant Examiner(s): ROSENBAUM, C FRED
• Application Number:
  US06/061,772
• Time in Patent Office: 585 Days
• Field of Search: 128/155-156, 128/283, 260/17.4 BB, 260/17.4 CL, 260/17.4 GC, 260/17.4 ST
• US Class Current: 604/336
• CPC Class Codes: A61L 24/043 Mixtures of macromolecular materials
• CPC Class Codes: A61L 2400/14 Adhesives for ostomy devices
• CPC Class Codes: C08L 23/22 Copolymers of isobutene; Butyl rubber ; Homo- or copolymers of other iso-olefins
• CPC Class Codes: C08L 5/00 Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
• CPC Class Codes: C08L 5/06 Pectin; Derivatives thereof

Abstract

An adhesive composition adapted for use with an ostomy appliance consisting of a mixture of a hydrocolloid gum, a pressure sensitive adhesive, and a cohesive strengthening agent. The cohesive strengthening agent is either an inert natural or synthetic fibrous material, finely divided cellulose, a cross-linked dextran, a cross-linked carboxymethylcellulose, or a starch-acrylonitrile graft copolymer.

Claims

1. A skin barrier comprising an adhesive layer having a thin continous or discontinuous polymeric film laminated to one surface of the adhesive, said adhesive consisting essentially of a substantially homogenous mixture on a percent weight basis of from about 15% to about 40% of guar gum, locust bean gum, or mixtures thereof;

from 0% to about 25% of pectin, gum karaya, or mixtures thereof provided that the total amount of guar gum, locust bean gum, gum karaya and pectin is from about 20% to about 55%;

from about 40% to about 60% of a mixture of a low molecular weight polyisobutylene having a viscosity average molecular weight of from about 36,000 to about 58,000 on the Flory scale and butyl rubber having a viscosity average molecular weight of from about 300,000 to about 450,000 on the Flory scale, said polyisobutylene and said butyl rubber combined in a ratio of from about 3 to 1 to about 5 to 1 on a weight basis; and

as a cohesive strengthening agent from about 2% to about 12% of an inert natural or synthetic fibrous material or from about 10% to about 30% of a finely divided cellulose, a finely divided substantially water insoluble cross-linked dextran, a finely divided substantially water insoluble cross-linked sodium carboxymethyl-cellulose, or a finely divided substantially water insoluble starch-acrylonitrile graft polymer.

2. The skin barrier of claim 1 wherein the cohesive strengthening agent is from about 2% to about 12% cotton.

3. The skin barrier of claim 2 said adhesive comprising from about 15% to about 40% guar gum;

from 0% to 25% pectin provided that the total amount of guar gum and pectin is from about 35% to about 55%; and

from about 45% to about 55% of the mixture of said low molecular weight polyisobutylene and said butyl rubber wherein the ratio of low molecular weight polyisobutylene to butyl rubber is about 4 to 1 on a weight basis.

4. The skin barrier of claim 3 said adhesive comprising about 5% cotton, about 28.5% guar gum, about 19% pectin, about 47.5% of a 4 to 1 mixture of polyisobutylene of a viscosity average molecular weight of about 36,000 to about 45,000 on the Flory scale and butyl rubber of a viscosity average molecular weight of about 425,000 on the Flory scale.

5. The skin barrier of claim 1 wherein the cohesive strengthening agent is from about 10% to about 30% finely divided purified wood cellulose.

6. The skin barrier of claim 5 said adhesive comprising from about 15% to about 40% guar gum;

from 0% to 25% pectin provided that the total amount of guar gum and pectin is from about 20% to 45%; and

from about 45% to about 55% of said mixture of low molecular weight polyisobutylene and said butyl rubber wherein the ratio of low molecular weight polyisobutylene to butyl rubber is about 4 to 1 on a weight basis.

7. The skin barrier of claim 6 said adhesive comprising about 20% finely divided purified wood cellulose, about 30% guar gum, and about 50% of a 4 to 1 mixture of polyisobutylene of a viscosity average molecular weight of about 36,000 to about 45,000 on the Flory scale and butyl rubber of a viscosity average molecular weight or about 425,000 on the Flory scale.

8. An ostomy bag having a faceplate to which a layer of adhesive is permanently bonded, said adhesive consisting essentially of a substantially homogenous mixture on a percent weight basis of from about 15% to about 40% of guar gum, locust bean gum, or mixtures thereof;

from 0% to about 25% of pectin, gum karaya, or mixtures thereof provided that the total amount of guar gum, locust bean gum, gum karaya and pectin is from about 20% to about 55%;

from about 40% to about 60% of a mixture of a low molecular weight polyisobutylene having a viscosity average molecular weight of from about 36,000 to about 58,000 on the Flory scale and butyl rubber having a viscosity average molecular weight from about 300,000 to about 450,000 on the Flory scale, said polyisobutylene and said butyl rubber combined in a ratio of from about 3 to 1 to about 5 to 1 on a weight basis; and

as a cohesive strengthening agent from about 2% to about 12% of an inert natural or synthetic fibrous material or from about 10% to about 30% of a finely divided cellulose, a finely divided substantially water insoluble cross-linked dextran, a finely divided substantially water insoluble cross-linked sodium carboxymethylcellulose, or a finely divided substantially water insoluble starch-acrylonitrile graft polymer.

9. The ostomy bag of claim 8, said adhesive consisting essentially of from about 15% to about 40% guar gum;

from 0% to 25% pectin provided that the total amount of guar gum and pectin is from about 35% to about 55%;

from about 45% to about 55% of the mixture of said low molecular weight polyisobutylene and said butyl rubber wherein the ratio of low molecular weight polyisobutylene to butyl rubber is about 4 to 1 on a weight basis; and

as the cohesive strengthening agent from about 2% to about 12% cotton.

10. The ostomy bag of claim 9, said adhesive consisting essentially of about 5% cotton, about 28.5% guar gum, about 19% pectin, about 47.5% of a 4 to 1 mixture of polyisobutylene of a viscosity average molecular weight of about 36,000 to about 45,000 on the Flory scale and butyl rubber of a viscosity average molecular weight of about 425,000 on the Flory scale.

11. The ostomy bag of claim 8, said adhesive consisting essentially of from about 15% to about 40% guar gum;

from 0% to 25% pectin provided that the total amount of guar gum and pectin is from about 20% to 45%;

from about 45% to about 55% of said mixture of low molecular weight polyisobutylene and said butyl rubber wherein the ratio of low molecular weight polyisobutylene to butyl rubber is about 4 to 1 on a weight basis; and

as the cohesive strengthening agent from about 10% to about 30% finely divided purified wood cellulose.

12. The ostomy bag of claim 11, said adhesive consisting essentially of about 20% finely divided purified wood cellulose, about 30% guar gum, and about 50% or a 4 to 1 mixture of polyisobutylene of a viscosity average molecular weight of about 36,000 to about 45,000 on the Flory scale and butyl rubber of a viscosity average molecular weight or about 425,000 on the Flory scale.