Methods of and apparatus for the measurement of blood pressure

• US 4,263,918 A
• Filed: 03/21/1977
• Issued: 04/28/1981
• Est. Priority Date: 03/21/1977
• Status: Expired due to Term

• Current Assignee: Creditanstalt-Bankverein (Unicredit SPA)
• Original Assignee: Biomega Corporation
• Inventors: Watson, Robert C., Swearingen, Jerry D.
• Primary Examiner(s): Michell, Robert W.
• Assistant Examiner(s): Jaworski, Francis J.
• Application Number:
  US05/779,374
• Time in Patent Office: 1,499 Days
• Field of Search: 128/2.05 A, 128/2.05 M, 128/2.05 Q, 128/2.05 T, 128/680-681, 364/417
• US Class Current: 600/494
• CPC Class Codes: A61B 5/02116 of pulse wave amplitude A61B5/02225 takes precedence
• CPC Class Codes: A61B 5/02225 using the oscillometric method

Abstract

Blood pressure is measured with the aid of a programmed data processor such as a microcomputer. Electrical signals are provided in response to the pressure in a blood pressure cuff as the pressure therein is changed to vary the constriction of an artery. The signals are processed to provide a train of pulses corresponding to successive blood pressure pulses and digital signals representing the amplitude of each pulse and the cuff pressure which accompanies each pulse are stored in the memories of the data processor. The processor has means by which the pulses are first selected in accordance with their relative amplitudes and location in the train so as to satisfy criteria for the rejection of artifacts. The processor provides outputs from its memories in which digital signals representing cuff pressures which were acquired at the same time as the pulses which are identified as occurring at the times of the systolic and diastolic events. These outputs may be displayed as on a digital readout device or processed for remote transmission so as to indicate the blood pressure. Information as to the pulse rate may be obtained from the time intervals between a group of pulses in the train by converting that time interval into a digital signal which represents the pulse rate. This signal may also be outputted to a display or for remote transmission.

Claims

1. The method of measuring blood pressure by the use of the arterial pressure pulses which accompany the temporary constriction of an artery by means of a compression cuff or the like, said method comprising the steps of

selecting, and storing signals corresponding to, a plurality of pulses which consist of the highest pulses in a group of said pressure pulses regardless of the order of their occurrence during said temporary constriction,

detecting from said highest pulses a reference level, and

then providing outputs corresponding to the pressure exerted by the blood in said artery upon occurrence of first and second pulses in said group, respectively preceding and following at least one of said highest pulses, which first and second pulses bear certain amplitude relationships to first and second levels which are in predetermined proportional relationship with said reference level, the one of said outputs provided upon occurrence of said first pulse corresponding to the systolic blood pressure and the other of said outputs provided upon occurrence of said second pulse corresponding to the diastolic blood pressure.

2. The invention as set forth in claim 1 further comprising the steps of

timing the occurrence of a number of said pressure pulses, said number being more than two, and

providing an output pulse rate corresponding to the time interval during which said number of said pulses occur.

3. The invention as set forth in claim 2 including the step of selecting said number of pulses for timing from those of said pressure pulses which occur approximately when one of said first and second pulses occurs.

4. The invention as set forth in claim 1 wherein said detecting step is carried out while said artery is being constricted.

5. The invention as set forth in claim 1 wherein said detecting step is carried out while the constriction of said artery is being released.

6. The invention as set forth in claim 1 wherein said method further comprises the step of

detecting the static pressure applied by said cuff and providing said outputs from the detected static pressures which are concurrent with said first and second pulses.

7. The invention as set forth in claim 1 wherein said predetermined proportional relationship which said first level bears to said reference level is approximately forty-five percent, and said proportional relationship which said second level bears to said reference level is seventy-five percent.

8. The invention as set forth in claim 7 wherein said amplitude relationships of said first pulse to said first level and said second pulse to said second level are:

that said first pulse is a member of a first set of three pulses, two of which are adjacent and have amplitudes lower than said first level and the other of which has an amplitude at east equal to said first level and is the closest of said pulses in said first set to said one highest amplitude pulse, said other pulse of said first set being said first pulse; and

that said second pulse is a member of a second set of three pulses, two of which are adjacent and have amplitudes lower then said second level and the other of which has an amplitude at least equal to said second level and is the closest of said pulses in said second set to said one highest amplitude pulse.

9. The method of obtaining information as to the vascular condition of a body comprising the steps of

producing a change in circulation through a blood vessel and generating electrical signals corresponding thereto,

translating said signals into a train of pulses which correspond to the pressure pulsations in said blood vessel as said circulation changes,

deriving from a plurality of pulses in said train which are of the highest amplitude pulses in said train and certain of which have predetermined amplitude relationship with respect to the pulse of highest amplitude in said plurality of pulses, a reference level corresponding to the average peak level thereof,

detecting those of said pulses in said train having amplitudes which are approximately of amplitudes which are certain percentages of said reference level, and

providing outputs representing said information from those of said electrical signals which are substantially coincidental with said pulses.

10. The invention as set forth in claim 9 wherein said detecting step is carried out by detecting first and second pulses which respectively precede and succeed at least one of said plurality of pulses of highest amplitude.

11. The invention as set forth in claim 10 wherein said detecting step is carried out by detecting, as said first pulse and second pulse, pulses having amplitudes which are different percentages of said reference level.

12. The invention as set forth in claim 11 wherein said first pulse is a member of a first set of at least three adjacent pulses in said train one of which is of amplitude equal to or greater than a first of said different percentages of said reference level and the others of which are of amplitudes less than said first percentage of said reference level, said first pulse being the one of said pulses in said pair of amplitude equal to or greater than said first percentage of said reference level and which is closest to said one pulse of highest amplitude, and wherein said second pulse is a member of a second set of at least three adjacent pulses in said train one of which is of amplitude equal to or greater than a second of said different percentages of said reference level and the others of which are of amplitude less than said second percentage of said reference level, said second pulse being the member of said second pair of amplitude equal to or greater than said second percentage of said reference level and which is closest to said one pulse of highest amplitude level.

13. The invention as set forth in claim 12 wherein said information is systolic and diastolic blood pressure and said first percentage is about 45% and said second percentage is about 75%, said output coincident with said first pulse representing said systolic pressure and said output coincident with said second pulse representing said diastolic pressure.

14. The invention as set forth in claim 13 including the steps of timing the duration of the total time between a plurality of pairs of said pulses which occur sequentially in said train, and

deriving another output representing pulse rate from the said duration of said sequentially occurring pulses.

15. The invention as set forth in claim 12 wherein said deriving step is carried out by selecting a set of pulses of highest amplitude, the highest amplitude one of which is at most 25% higher than the amplitude of the lowest pulses in said set and said highest amplitude one of said pulses is no more than 150% of both of a pair of pulses which are consecutive therewith and are next adjacent thereto.

16. The invention as set forth in claim 15 including the step of detecting an error in said information when less than a certain number of pulses occur in said train.

17. The invention as set forth in claim 16 wherein said error detecting step includes detecting an error when said first pulse is the first pulse in said train.

18. The invention as set forth in claim 17 wherein said error detecting step includes detecting an error when less than a certain number of pulses occur in said train after said second pulse.

19. The method of obtaining information as to blood pressure comprising the steps of

providing electrical signals corresponding to the constriction pressure exerted on a blood vessel as the constriction thereof is changed,

translating said electrical signals into a train of successive pulses each corresponding to a successive pulsation of said vessel and having an amplitude which is a function of the pulsatile component of the blood pressure,

translating said electrical signals into first digital signals each corresponding to a different one of said pulses in said train and representing the amplitude of said electrical signals when each of said pulses in said train occur, which first digital signals represent the constriction pressure on said vessel,

storing all said first digital signals,

storing all second digital signals representing the amplitudes of said pulses in said train,

developing from said pulses in said train a reference level corresponding to the average of the amplitudes of a set of those of said pulses in said train which are of highest amplitude level regardless of where they occur in said train,

identifying from said stored second digital signals first and second pulses in said train respectively having amplitudes at least equal to a systolic threshold level and a diastolic threshold level each of which are different percentages of said reference level, and

displaying as systolic blood pressure and as diastolic blood pressure the values of said first digital signals respectively corresponding to said first pulse and to said second pulse.

20. The invention as set forth in claim 19 wherein said developing step includes the steps of storing a peak table of third digital signals which correspond to those pulses in said train which are of highest amplitude, said third digital signals each representing the amplitude of a different one of said highest amplitude pulses,

selecting those of said third digital signals which correspond to three pulses in said train and have amplitudes, the highest of which is at most a first predetermined percentage of the smallest and the highest of which is at most a second predetermined percentage of the amplitudes of each of the pair of pulses next adjacent thereto in said train, said three pulses constituting said set, and

obtaining from said third digital signals corresponding to the pulses in said set, a digital signal representing said reference level.

21. The invention as set forth in claim 20 wherein said identifying step includes the step of selecting said first and second pulses from said stored second digital signals located on opposite sides of the one of said second digital signals which corresponds to one of said highest amplitude pulses, said vessel being in a more constricted condition while the pulses on the one of said opposite sides which includes said first pulse are being produced than while the pulses on the other of said opposite sides which include said second pulse are being produced, and said first and second pulses being members of first and second sets of at least three pulses which correspond to digital signals of values one of which is at least equal to said systolic and diastolic threshold values respectively and the other two of which are both less than said systolic and diastolic threshold values respectively, said one pulse of said set being closest to said highest amplitude pulses and said first and second pulses being said one pulses of their respective sets.

22. The invention as set forth in claim 21 including the step of measuring the intervals of time between the pulses of each pair of pulses in said train and inhibiting the displaying of said pressures if more than a predetermined number of said intervals are greater than a given length.

23. The invention as set forth in claim 22 including the step of inhibiting the displaying of said systolic pressure if said first pulse corresponds to the one of said second digital signals which is located at an end of said table.

24. The invention as set forth in claim 23 including the step of also inhibiting the displaying of said pressures if less than a certain number of second digital signals are stored.

25. The invention as set forth in claim 24 including the step of also inhibiting the displaying of said pressures unless the values of the one of the first digital signals corresponding to said first pulse is at least the sum of the value of said first digital signal corresponding to said second pulse and a value corresponding to a certain pressure which is lower than any normal blood pressure difference between systolic and diastolic pressures.

26. The invention as set forth in claim 20 wherein the constriction of said vessel is changed by applying pressure with the aid of a cuff externally to the body member which carries said blood vessel and releasing said pressure, and said step of providing electrical signals is carried out by transducing said cuff pressure into said electrical signals as said cuff pressure changes in one of two opposite senses, in the first of which said pressure is applied and in the second of which said pressure is released, and wherein said step of storing said second digital signals is carried out to provide a pulse table of said second digital signals representing the heights of said pulses as said cuff pressure changes in said one sense from a first cuff pressure to a second cuff pressure, and said step of storing said first digital signals is carried out to provide a cuff table of said first digital signals representing the static pressure presented by said cuff when each of said pulses occur as said cuff pressure changes from said first cuff pressure to said second cuff pressure, and said steps of storing said first and second digital signals in said pulse table and in said cuff table are carried out until certain digital signals in said tables satisfy predetermined criteria.

27. The invention as set forth in claim 26 wherein said criteria are that

(a) at least a certain number of said second digital signals are stored in said pulse table after the storage of the one of said second digital signals which corresponds to a pulse near the middle of said peak table between approximately like numbers of digital signals corresponding to pulses of higher amplitude and of lower amplitude which are also stored in said peak table,

(b) the one of said first digital signals in said cuff table which represents the last cuff pressure in said cuff table has a value which is predetermined by the value of the third digital signal representing the lowest one of the pulses in said peak table, and

(c) there are at least two consecutive second digital signals stored in said pulse table after the storage of said one of said second digital signals which corresponds to said pulse near the middle of said peak table which represents values below a predetermined threshold value corresponding to a predetermined percentage of the average of the three lowest third digital signals in said peak table.

28. The invention as set forth in claim 27 wherein said first and second digital signals are stored in said pulse table and said cuff table nevertheless until said tables are fully occupied even if any of said criteria remain unsatisfied.

29. The invention as set forth in claim 27 wherein said systolic threshold value is 0.45 times the said average from the amplitudes of said set of three highest third digital signals in said peak table and said diastolic threshold is 0.75 times said last named average.

30. The invention as set forth in claim 27 including the step of obtaining information respecting pulse rate by first measuring the time interval for the occurrence of a group of said pulses the first of which occurs after the occurrence of a plurality of pulses commencing with the pulse following the pulse which corresponds to the digital signal in said peak table having the lowest amplitude, obtaining said pulse rate information in terms of the average rate at which the pulses in said group occurs.

31. The invention as set forth in claim 27

wherein said identifying step includes the steps of obtaining from said reference level said diastolic threshold level in terms of the product of average level of the pulses in said set and a factor which is about 0.75,

obtaining from said reference level said systolic threshold in terms of the product of said average level of the pulses in said set and a factor which is about 0.45,

selecting a set of said second digital signals in said pulse table from those second digital signals therein which correspond to three consecutive pulses more than two pulses beyond the pulse which is located in the middle of said peak table on the side of said middle pulse in the direction of lower cuff pressures, which said set of second digital signals represent two values below said diastolic threshold level and one value at least equal to said diastolic threshold level, said digital signal having a said one value corresponding to said second pulse, and

selecting another set of second digital signals in said pulse table from those second digital signals which correspond to three consecutive pulses more than two pulses beyond the pulse which is located in the middle of said peak table in the direction of higher cuff pressures, which said another set of second digital signals represent two values below and one value at least equal to said systolic threshold level, said digital signal having said one value corresponding to said first pulse.

32. Apparatus for obtaining physiological information from the pressure exerted by a blood vessel which comprises

(a) means for producing a pair of electrical signals a first of which is a function of the pressure exerted by said blood vessel as a changing constricting pressure is applied thereto and a second of which is a function of the pulsatile component of said pressure and is in the form of a train of pulses each for a successive blood pressure pulse,

(b) means for converting said first and second signals into first and second digital signals,

(c) a programmed data processor responsive to said first and second digital signals having means for

(1) acquiring and storing said first and second digital signals upon occurrence of each of said pulses and a group of said second digital signals of highest amplitudes,

(2) locating one of said second digital signals the value of which has a certain relationship to the average of the peak value of a plurality of the second digital signals in said group, and was acquired after a member of said second digital signals in said group when said constricting pressure changes in a decreasing sense and before said member of second digital signals in said group when said constricting pressure changes in an increasing sense,

(3) producing an output corresponding to the value of said first digital signal which is acquired for the same one of said pulses in said train as said one of said second digital signals to represent the diastolic blood pressure.

33. The invention as set forth in claim 32 wherein said programmed data processor further comprises means for

(4) locating another of said second digital signals the value of which has another certain amplitude relationship to said average of the peak value of second digital signals in said group, and was acquired before said member of said second digital signals in said group when said constricting pressure changes in a decreasing sense and after said second digital signals in said group when said constricting pressure changes in an increasing sense, and

(5) producing another output corresponding to the value of said first digital signal which is acquired for the same one of said pulses as said another of said second digital signals to represent the systolic blood pressure.

34. The invention as set forth in claim 33 wherein said processor further comprises means for

(6) eliminating the effect of pulses which are artifacts including means for including in said group only such of said second digital signals which have values which satisfy certain relationships.

35. The invention as set forth in claim 34 wherein said processor further comprises means for

(7) computing pulse rate from the time interval for the acquisition of a plurality of said digital signals in another group which are acquired after said first named group.

36. The invention as set forth in claim 35 wherein said programmed data processor is a microcomputer having memories for the storage of the program and for said first and second groups of digital signals.

37. The invention as set forth in claim 36 wherein said apparatus further comprises display means responsive to said outputs from said processor for indicating the numerical value of said systolic and diastolic pressures and said pulse rate.

38. The invention as set forth in claim 32 wherein said means for producing said electrical signals includes transducer means for providing an analog signal which is proportional to said pressure, said analog signal providing said first signal, and means for filtering said analog signal so as to pass frequencies in said pulsatile component for providing said second signal.

39. The invention as set forth in claim 38 wherein said converting means includes analog to digital converter means, switching circuit means for selectively applying one of said first and second signals to said analog to digital converter means, and means for generating a control signal in response upon occurrence of each pulse of said second signal, said processor also having means responsive to said control signals for operating said switching means to apply said second signal to said analog to digital conversion means whereby to present said first and second digital signals to said processor for acquisition upon occurrence of each of said pulses in said train.

40. Apparatus for obtaining information as to the vascular condition of a body comprising

means for producing a change in circulation through a blood vessel and generating electrical signals corresponding thereto,

means for translating said signals into a train of pulses which correspond to the pressure pulsations in said blood vessel as said circulation changes,

means for deriving from a plurality of pulses in said train which are of the highest amplitude and certain of which have predetermined amplitude relationships with the pulse of highest amplitude in said plurality of pulses a reference level corresponding to the average peak level thereof,

means for detecting those of said pulses in said train having amplitudes which are approximately of amplitudes which are certain percentages of said reference level, and

means for providing outputs representing said information from those of said electrical signals which are substantially coincidental with said pulses.

41. The invention as set forth in claim 40 wherein said detecting means includes means for detecting first and second pulses which respectively precede and succeed at least one of said pulses of highest amplitude.

42. The invention as set forth in claim 41 wherein said first and second pulses detecting means includes means for detecting, as said first pulse and second pulses, pulses having amplitudes which are different percentages of said reference level.

43. The invention as set forth in claim 42 wherein first and second pulse detecting means include

(a) means for detecting said first pulse when said first pulse is a member of a first set of at least three adjacent pulses in said train one of which is of amplitude equal to or greater than a first of said different percentage of said reference level and the others of which are of amplitudes less than said first percentage of said reference level, said first pulse being the one of said pulses in said pair of amplitude equal to or greater than said first percentage of said reference level and which is closest to said one pulse of highest amplitude, and

(b) means for detecting said second pulse when said second pulse is a member of a second set of at least three adjacent pulses in said train one of which is of amplitude equal to or greater than a second of said different percentages of said reference level and the others of which are of amplitude less than said second percentage of said reference level, said second pulse being the member of said second pair of amplitude equal to or greater than said second percentage of said reference level and which is closest to said one pulse of highest amplitude level.

44. The invention as set forth in claim 43 wherein said information is systolic and diastolic blood pressure and said detecting means includes means for establishing said first percentage as about 45% and said second percentage as about 75%, whereby said outputs providing means provides the one of said outputs which is coincident with said first pulse as representing said systolic pressure and the other of said outputs which is coincident with said second pulse as representing said diastolic pressure.

45. The invention as set forth in claim 44 further comprising means for timing the duration of the total time between a plurality of pairs of said pulses which occur sequentially in said train, and

means for deriving another output representing pulse rate from the said duration of said sequentially occurring pulses.

46. The invention as set forth in claim 43 wherein said deriving means includes means for selecting a set of pulses of highest amplitude, the highest amplitude one of which is at most 25% higher than the amplitude of the lowest pulses in said set and said highest amplitude one of said pulses is no more than 150% of both of a pair of pulses which are consecutive therewith and are next adjacent thereto.

47. The invention as set forth in claim 46 including means for detecting an error in said information when less than a certain number of pulses occur in said train.

48. The invention as set forth in claim 47 wherein said error detecting means also includes means for detecting an error when said first pulse is the first pulse in said train.

49. The invention as set forth in claim 48 wherein said error detecting means also includes means for detecting an error when less than a certain number of pulses occur in said train after said second pulse.

50. Apparatus for obtaining information as to the vascular condition of a body comprising

means for producing a change in circulation through a blood vessel and generating electrical signals corresponding thereto,

means for translating said signals into a train of pulses which correspond to the pressure pulsations in said blood vessel as said circulation changes,

means for selecting certain pulses in said train which comprises an envelope detector for providing an output signal which follows the peaks of the pulses in said train, a peak detector which provides an output signal having an amplitude corresponding to the peak amplitude of that envelope detector output signal, multiplier means for providing a systolic threshold level which is a certain percentage of said peak detector signal level and a diastolic threshold level which is another percentage of said peak detector output level, comparators for outputting trigger signals when said envelope reaches said systolic reference level and said diastolic threshold level, respectively, and

means for providing outputs representing said information includes means operated by said trigger signals for producing as said outputs, signals corresponding to the amplitude of said electrical signals which correspond to the circulation through said blood vessel upon occurrence of said systolic trigger signal and upon occurrence of said diastolic trigger signal, the amplitude of said electrical signals produced upon occurrence of said systolic trigger signal being a measure of the systolic blood pressure in said vessel and the amplitude of said electrical signal produced upon occurrence of said diastolic trigger being a measure of the diastolic blood pressure in said blood vessel.

51. Apparatus for obtaining information as to blood pressure comprising

means for providing electrical signals corresponding to the constriction pressure exerted on a blood vessel as the constriction thereof is changed,

means for translating said electrical signals into a train of successive pulses each corresponding to a successive pulsation of said vessel and having an amplitude which is a function of the pulsatile component of the blood pressure,

means for translating said electrical signals into first digital signals each corresponding to a different one of said pulses in said train and representing the amplitude of said electrical signals when each of said pulses in said train occur, which first digital signals represent the constriction pressure on said vessel,

means for storing all said first digital signals,

means for storing all second digital signals representing the amplitudes of said pulses in said train,

means for developing from said pulses in said train a reference level corresponding to the average of the amplitudes of a set of those of said pulses in said train which are of highest amplitude level regardless of where they occur in said train,

means for identifying from said stored second digital signals first and second pulses in said train respectively having amplitudes at least equal to a systolic threshold level and a diastolic threshold level each of which are different percentages of said reference level, and

means for displaying as said systolic blood pressure and as said diastolic blood pressure the values of said first digital signals respectively corresponding to said first pulse and to said second pulse.

52. The invention as set forth in claim 51 wherein said developing means includes

(i) means for storing a peak table of third digital signals which correspond to those pulses in said train which are of highest amplitude, said third digital signals each representing the amplitude of a different one of said highest amplitude pulses,

(ii) means for selecting those of said third digital signals which correspond to three pulses in said train and have amplitudes, the highest of which is at most a first predetermined percentage of the smallest and the highest of which is at most a second predetermined percentage of the amplitudes of each of the pair of pulses next adjacent thereto in said train, said three pulses constituting said set, and

(iii) means for obtaining from said third digital signals corresponding to the pulses in said set, a digital signal representing said reference level.

53. The invention as set forth in claim 52 wherein said identifying means includes means for selecting said first and second pulses from said stored second digital signals located on opposite sides of the one of said second digital signals which corresponds to said highest amplitude pulse, said vessel being in a more constricted condition while the pulses on the one of said opposite sides which includes said first pulse are being produced than while the pulses on the other of said opposite sides which include said second pulse are being produced, and said first and second pulses being members of different sets of at least three pulses which correspond to digital signals of values one of which is at least equal to said threshold values and the other two of which are both less than said threshold values, said one pulse of said set being closest to said highest amplitude pulses and said first and second pulses being said one pulses of their respective sets.

54. The invention as set forth in claim 53 including means for measuring the intervals of time between the pulses of each pair of pulses in said train, and means for inhibiting said means for displaying said pressures if more than a predetermined number of said intervals are greater than a given length.

55. The invention as set forth in claim 54 including means for inhibiting said means for displaying said systolic pressure if said first pulse corresponds to the one of said second digital signals which is located at an end of said table.

56. The invention as set forth in claim 55 including means for also inhibiting said means for displaying said pressures if less than a certain number of second digital signals are stored.

57. The invention as set forth in claim 56 including further means for inhibiting said means for displaying said pressures unless the values of the one of the first digital signals corresponding to said first pulse is at least the sum of the value of said first digital signal corresponding to said second pulse and a value corresponding to a certain pressure which is lower than any normal blood pressure difference between systolic and diastolic pressures.

58. The invention as set forth in claim 52 including cuff means for changing the constriction of said vessel which applies pressure externally to the body member which carries said blood vessel and which releases said pressure;

and said means for providing said electrical signals includes means for transducing the pressure at said cuff means into said electrical signals as said cuff means pressure changes in one of two opposite senses, in the first of which said pressure is applied and in the second of which said pressure is released; and

wherein said means for storing said second digital signals is operative to establish a pulse table of said second digital signals representing the heights of said pulses as said cuff means pressure changes in said one sense from a first cuff pressure to a second cuff pressure; and

said means for storing said first digital signals is operative to establish a cuff table of said first digital signals representing the static pressure presented by said cuff means when each of said pulses occur as said cuff means pressure changes from said first cuff pressure to said second cuff pressure, and said means for storing said first and second digital signals in said pulse table and in said cuff table are operative to store said first and second digital signals in said tables until certain digital signals in said tables satisfy predetermined criteria.

59. The invention as set forth in claim 58 wherein said storing means includes means responsive to said first and second digital signals for storing said signals in said cuff table and pulse table until said criteria which are met are that

(a) at least a certain number of said second digital signals are stored in said pulse table after the storage of the one of said second digital signals which corresponds to a pulse near the middle of said peak table between approximately like numbers of digital signals corresponding to pulses of higher amplitude and of lower amplitude which are also stored in said peak table,

(b) the one of said first digital signals in said cuff table which represents the last cuff pressure in said cuff table has a value which is predetermined by the value of the third digital signal representing the lowest one of the pulses in said peak table, and

(c) there are at least two consecutive second digital signals stored in said pulse table after the storage of said one of said second digital signals which corresponds to said pulse near the middle of said peak table which represents values below a predetermined threshold value corresponding to a predetermined percentage of the average of the three lowest third digital signals in said peak table.

60. The invention as set forth in claim 59 wherein means included in said storing means includes means for storing said first and second digital signals in said cuff table and said pulse table nevertheless until said tables are fully occupied if any of said criteria remain unsatisfied.

61. The invention as set forth in claim 60 including means for developing said systolic threshold value which is 0.45 times the said average from the amplitude of said set of three highest third digital signals in said peak table and for developing said diastolic threshold which is 0.75 times said last named average.

62. The invention as set forth in claim 60 including means for obtaining information respecting pulse rate operative first to measure the time interval for the occurrence of a group of said pulses the first of which occurs after the occurrence of a plurality of pulses commencing with the pulse following the pulse which corresponds to the digital signal in said peak table having the lowest amplitude, and means for obtaining said pulse rate information in terms of the average rate at which the pulses in said group occurs.

63. The invention as set forth in claim 60 wherein said identifying means includes

(a) means for obtaining from said reference level said diastolic threshold level in terms of the product of average level of the pulses in said set and a factor which is about 0.75,

(b) means for obtaining from said reference level said systolic threshold in terms of the product of said average level of the pulses in said set and a factor which is about 0.45,

(c) means for selecting a set of said second digital signals in said pulse table from those second digital signals therein which correspond to three consecutive pulses more than two pulses beyond the pulse which is located in the middle of said peak table on the side of said middle pulse in the direction of lower cuff pressures, which said set of second digital signals represent two values below said diastolic threshold level and one value at least equal to said diastolic threshold level said digital signal having a said one value corresponding to said second pulse, and

(d) means for selecting another set of second digital signals in said pulse table from those second digital signals which correspond to three consecutive pulses more than two pulses beyond the pulse which is located in the middle of said peak table in the direction of higher cuff pressures, which said another set of second digital signals represent two values below and one value at least equal to said systolic threshold level, said digital signal having said one value corresponding to said first pulse.

64. The method of measuring blood pressure by the use of the arterial pressure pulses of varying amplitude which accompany the temporary constriction of an artery by means of a compression cuff or the like, said method comprising translating said pulses into corresponding electrical signals, storing digital signals corresponding to the amplitudes of said electrical signals, deriving from said stored digital signals a reference level related to at least one of said digital signals which corresponds to a pressure pulse of highest amplitude and a predetermined threshold level which is less than said reference level, selecting a plurality of said stored signals corresponding to a plurality of successive ones of said pulses the amplitudes of which and said threshold bear a predetermined relationship with each other, and then providing an output corresponding to the pressure exerted by the blood in said artery upon occurrence of a selected one of said plurality of successive ones of said pulses.

65. A system for measuring blood pressure by the use of the arterial pressure pulses of varying amplitude which accompany the temporary constriction of an artery by means of a compression cuff or the like, said system comprising means for translating said pulses into corresponding electrical signals, means for storing digital signals corresponding to the amplitudes of said electrical signals, means for deriving from said stored digital signals a reference level related to at least one of said digital signals corresponding to a pressure pulse of highest amplitude and the predetermined threshold level which is less than said reference level, means for selecting a plurality of said stored signals corresponding to a plurality of successive ones of said pulses, the amplitudes of which and said threshold level bear a predetermined relationship, and means for providing an output corresponding to the pressure exerted by the blood in said artery upon occurrence of a selected one of said successive ones of said plurality of pulses.