Stable mouthwash compositions containing zinc and fluoride compounds

• US 4,289,755 A
• Filed: 11/03/1980
• Issued: 09/15/1981
• Est. Priority Date: 11/03/1980
• Status: Expired due to Term

• Current Assignee: Topol-Dep Corporation
• Original Assignee: Richardson-Vicks, Inc. (The Procter & Gamble Company)
• Inventors: Dhabhar, Dadi J.
• Primary Examiner(s): Rose, Shep K.
• Application Number:
  US06/203,634
• Time in Patent Office: 316 Days
• Field of Search: 424/49-58
• US Class Current: 424/52
• CPC Class Codes: A61K 8/21 Fluorides; Derivatives thereof
• CPC Class Codes: A61K 8/27 Zinc; Compounds thereof
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

A stable mouthwash composition is provided with acceptable astringency and without loss of anti-odor properties, and improved compatibility with fluoride ions.

Claims

1. A stable mouthwash composition containing zinc and fluoride compounds comprising a mouthwash carrier, from about 0.1 to about 15% by weight zinc citrate, from about 0.01 to about 1% by weight sodium fluoride, an amount of citric acid sufficient to solvate the zinc citrate and an amount of an alkali compound sufficient to adjust the pH of the mouthwash composition to a pH within the range of pH 6.0 to 7.2.

2. A stable mouthwash composition of claim 1 wherein the amount of citric acid present is an amount of from about 1.5 to about 10 moles citric acid per 1 mole of zinc citrate.

3. A stable mouthwash composition of claim 2 wherein the amount of citric acid present is an amount of from about 2.5 to about 3.5 moles per 1 mole of zinc citrate.

4. A stable mouthwash composition of claim 3 wherein the amount of citric acid present is an amount of about 2.76 moles per 1 mole of zinc citrate.

5. A mouthwash composition of claim 3 wherein the alkali compound is an alkali metal or ammonium hydroxide.

6. A mouthwash composition of claim 5 wherein the alkali compound is sodium hydroxide.

7. A mouthwash composition of claim 6 wherein the mouthwash carrier comprises about 5 to 40% by weight ethyl alcohol, about 0 to 20% by weight humectant, about 0 to 12% by weight surface active agent, about 0 to 0.5% by weight sweetening agent, about 0 to 0.31% by weight flavoring agent, and the balance distilled water.