Tremor measurement device

• US 4,306,291 A
• Filed: 12/14/1979
• Issued: 12/15/1981
• Est. Priority Date: 03/27/1979
• Status: Expired due to Term

• Current Assignee: Alcoholism And Drug Addiction Research Foundation
• Original Assignee: Alcoholism And Drug Addiction Research Foundation
• Inventors: Durand, Dominique M., Kaplan, Howard L., Zilm, Duane H.
• Primary Examiner(s): Wise, Edward J.
• Application Number:
  US06/103,685
• Time in Patent Office: 732 Days
• Field of Search: 364/421, 364/508, 128/739, 128/733, 73/649
• US Class Current: 600/552
• CPC Class Codes: A61B 5/1101 Detecting tremor
• CPC Class Codes: A61B 5/4082 Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F

Abstract

Apparatus is provided in which a signal indicative of the tremor is sensed. This signal is amplified in a variable gain amplifier. During an initial time interval the size of the amplifier signal is determined and the gain of the amplifier is adjusted in response to the signal size. Then means are provided for indicating the size of frequency of the adjusted signal during a further time period to give a tremor measurement which may be relatively easily interpreted.

Claims

1. Apparatus for measuring tremor in a part of a living body, including means for sensing tremor and providing an electrical signal indicative of said tremor, variable gain amplifier means for amplifying said signal, means for sensing the size of said amplified signal during an initial predetermined period of time, means responsive to said signal size sensing means to adjust the variable gain of said amplifier means to a suitable level, and means for determining and indicating the size and frequency of the signal of adjusted amplification during a further predetermined period of time.

2. Tremor measuring apparatus according to claim 1, wherein the signal size sensing means comprises means for rectifying and integrating said signal, means for resetting said integrating means when the integral of said signal reaches a predetermined level, and said responsive means comprises means for counting the number of times the integral means is reset during said initial predetermined period of time and adjusting said amplifier means accordingly.

3. Tremor measuring apparatus according to claim 2, wherein said responsive means includes a programmed memory of suitable gain values for said amplifier means corresponding to the number of times the integral means is reset during said initial predetermined period of time, and said responsive means adjusts said amplifier means in accordance with the gain value in said memory corresponding to said number of resets.

4. Apparatus as claimed in claim 2 further including means for determining and indicating the mean of the mean square signal size and mean of the signal frequencies of a plurality of predetermined periods.

5. Tremor measuring apparatus according to claim 1, wherein said indicating means includes means for measuring and squaring the size of said signal of adjusted amplification at intervals during said further predetermined period of time, and means for calculating and indicating the mean squared sizes.

6. Apparatus as claimed in claim 5 further including means for determining and indicating the mean of the mean square signal size and mean of the signal frequencies of a plurality of predetermined periods.

7. Tremor measuring apparatus according to claim 1, further including means for detecting and indicating the dominant frequency of the tremor signal.

8. Tremor measuring apparatus according to claim 7, wherein said frequency detecting means includes means for counting the number of times the tremor signal crosses a zero line during said further predetermined period of time.

9. Apparatus as claimed in claim 7 further including means for determining and indicating the mean of the mean square signal size and mean of the signal frequencies of a plurality of predetermined periods.

10. Tremor measuring apparatus according to claim 1, wherein said tremor sensing means comprises an accelerometer.

11. Apparatus as claimed in claim 10 further including means for determining and indicating the mean of the mean square signal size and means of the signal frequencies of a plurality of predetermined periods.

12. Tremor measuring apparatus according to claim 1, wherein the signal size sensing means comprises means for rectifying and integrating said signal, means for resetting said integrating means when the integral of said signal reaches its predetermined level, said responsive means comprises means for counting the number of times the integral means is reset during said initial predetermined period of time and adjusting said amplifier means accordingly, and said indicating means includes means for measuring and squaring the size of said signal of adjusted amplification at intervals during said further predetermined period of time, and means for calculating and indicating the mean of the squared sizes.

13. Apparatus as claimed in claim 12 further including means for determining and indicating the mean of the mean square signal size and mean of the signal frequencies of a plurality of predetermined periods.

14. An apparatus as claimed in claim 1 further including means for determining and indicating the mean of the mean square signal size and mean of the signal frequencies of a plurality of predetermined periods.