Multiple microwave applicator system and method for microwave hyperthermia treatment

• US 4,397,313 A
• Filed: 08/03/1981
• Issued: 08/09/1983
• Est. Priority Date: 08/03/1981
• Status: Expired due to Fees

• Current Assignee: NationsBank of Texas NA (Bank of America Corp.)
• Original Assignee: Clini-Therm Corporation
• Inventors: Vaguine, Victor A.
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): Yanulis, George
• Application Number:
  US06/289,126
• Time in Patent Office: 736 Days
• Field of Search: 128/399, 128/400, 128/401, 128/419 N, 128/422, 128/736, 128/783, 128/804, 219/10.55 A, 219/10.55 F, 219/10.55 M, 219/10.55 R, 343/757, 343/758, 343/759, 343/760, 343/761, 343/762
• US Class Current: 607/104
• CPC Class Codes: A61N 5/02 using microwaves

Abstract

Multiple microwave applicators are configured to optimize the treatment in a hyperthermia system. Individual applicators are positioned for incrementally varying the treatment field size by the addition or subtraction of individual applicators. A fan beam geometric configuration may be utilized with individual applicators for producing a concave electric field for focusing the electromagnetic energy at a particular region of the body. The microwave applicator system may be positioned either in direct or indirect contact with a treatment area by positioning individual applicators to conform to the contours of the surface treatment area. The applicators may be combined to provide a continuing electromagnetic field pattern.

Claims

1. A multiple microwave applicator unit for use in a microwave hyperthermia treatment system including a source of microwave power, comprising:

a plurality of microwave waveguide applicators combined to form a microwave applicator unit;

means for microwave input power coupling said applicators to a source of microwave power;

means for selectively adding and removing individual applicators from among said plurality of applicators from coupling with said source of microwave power so as to incrementally increase or decrease the resultant treatment field size; and

means for positioning the geometry of said applicators, whereby the heating pattern may be controlled in a treatment area by shaping the propagated electromagnetic field and said plurality of applicators may be configured to conform to the contour of the treatment surface area, said plurality of microwave applicators being operated in a transverse electric mode whereby the electric field generated by the applicators is generally parallel the contour of the surface treatment area to minimize heating of healthy surface tissue.

2. The multiple microwave applicator unit of claim 1, wherein said microwave input power coupling is a magnetic coupling means.

3. The multiple microwave applicator unit of claim 1, wherein said plurality of applicators are operated in the incoherent mode, whereby the heating pattern is the sum of the heating pattern produced by each of said applicators.

4. The multiple microwave applicator unit of claim 1, wherein said applicators are operated in the coherent mode.

5. The multiple microwave applicator unit of claim 1, wherein said individual applicators are adjusted in a fan beam geometric configuration, whereby the microwave radiation is focused into an area of the patient selected for treatment.

6. The multiple microwave applicator unit of claim 5, wherein the angle of separation between said individual applicators is equal.

7. The multiple microwave applicator unit of claim 5, wherein the angle of separation between said individual applicators is unequal.

8. The microwave applicator unit of claim 1, wherein said applicators are operated in the fundamental transverse electric mode.

9. The microwave applicator unit of claim 1, wherein said applicators are operated in a higher order transverse electric mode.

10. The microwave applicator unit of claim 1, wherein said waveguide applicators are rectangular waveguides.

11. The microwave applicator unit of claim 1, wherein said waveguide applicators are cylindrical waveguides.

12. The microwave applicator unit of claim 1, wherein said waveguide applicators are elliptical waveguides.

13. The microwave applicator unit of claim 1, wherein said waveguide applicators are aligned to have their sidewalls substantially parallel, whereby a continuing electromagnetic field pattern is formed.

14. The microwave applicator unit of claim 1, wherein said plurality of applicators are sufficient in number and are adjusted to surround a region of a patient'"'"'s body, whereby the electric field is substantially parallel to the contour of the region of the patient'"'"'s body to be treated.

15. The microwave applicator unit of claim 14, whereby the open ends of said plurality of applicators are contiguous.

16. The method of operating a multiple microwave applicator unit of a microwave hyperthermia system in the incoherent mode to treat a patient, each applicator having an axis of propagation, comprising:

generating microwave power to each of said applicators from an independent microwave power source;

magnetically coupling microwave power from each of said independent power sources to each of said applicators such that the magnetic field propagated through each of said applicators is parallel to the axis of propagation;

operating each of said microwave applicators in the fundamental transverse electric mode; and

positioning the geometric configuration of said applicators relative to the contour of the patient surface treatment area for shaping the resultant magnetic field produced by said applicators, whereby the overall heating pattern for the hyperthermia system may be optimized for a particular treatment and the electric field will generally be parallel to the contour of the patient surface treatment area to minimize heat generation in healthy tissue.

17. The method of operating a hyperthermia treatment system with multiple microwave applicators in the incoherent mode, said applicators having an axis of propagation, comprising:

generating a single source of microwave power for distribution to each of the individual microwave applicators;

switching the source of microwave power sequentially from one of said applicators to another of said applicators;

magnetically coupling the microwave power source switched to each of said applicators, such that the magnetic field propagated through said applicators is parallel to the axis of propagation;

operating each of said microwave applicators in the fundamental transverse electric mode; and

positioning the geometric configuration of said applicators to shape the resultant electromagnetic field produced by the summation of each independent applicator for optimizing the heating pattern for a hyperthermia treatment.

18. The method of operating a hyperthermia treatment system with multiple microwave applicators in the incoherent mode, each applicator having an axis of propagation, comprising:

generating an electromagnetic microwave signal;

dividing said generated microwave signal equally for each of said applicators of the multiple applicator unit;

transmitting one of said divided microwave signals to an applicator selected as the reference applicator;

phase shifting each of said other divided microwave signals for modulating the phase of said microwave signals at a time to operate the applicators in the incoherent mode;

transmitting each of said phase shifted microwave signals to said other applicators;

operating each of said applicators in the fundamental transverse electric mode;

means for magnetically coupling each of said applicators to its phase shifted microwave signal source for aligning the magnetic field propagated through said applicators parallel to the applicator axis of propagation; and

positioning the geometry of said applicators to shape the resultant propagated electromagnetic field to optimize the overall heating pattern for a hyperthermia treatment.

19. The method of operating a hyperthermia treatment system with multiple applicators in the coherent mode, said applicators having an axis of propagation, comprising:

generating a single microwave signal;

dividing said generated microwave signal equally among said applicators;

transmitting said divided microwave signal to one of said applicators selected as the reference applicator;

adjusting variable phase shifters with respect to the reference phase of the microwave signal transmitted to said reference applicator to provide a coherent electromagnetic wave propagated from said applicators;

means for magnetically coupling each of said applicators to its microwave signal, such that the magnetic wave propagated through said applicator is parallel to the axis of propagation;

operating the applicators in the fundamental transverse electric mode; and

positioning the geometry of said applicators to shape the resultant propagated electromagnetic wave to achieve the optimum heating pattern for a hyperthermia treatment.

20. A microwave applicator system for use in conjunction with a source of microwave power for a microwave hyperthermia system, comprising:

a plurality of microwave waveguide applicators;

means for microwave input power coupling said applicators to a source of microwave power;

means for operating said applicators in a transverse electric mode; and

means for positioning said applicators about a surface treatment area with the electric field component of the propagated wave substantially parallel to the contour of the surface treatment area, whereby the heating of healthy surface tissue from the electric field component is minimized.

21. The microwave applicator of claim 20, wherein the open ends of said applicators are contiguous, whereby the resultant field produced by said applicators is substantially continuous.

22. A method of operating a microwave applicator system for use in conjunction with a source of microwave power for a microwave hyperthermia system including the steps of:

coupling a plurality of microwave waveguide applicators to the source of microwave power;

operating said plurality of microwave waveguide applicators in a transverse electric mode; and

positioning said plurality of applicators about a surface treatment area with the electric field component of the propagated wave substantially parallel to the contour of the surface treatment area, whereby the heating of healthy surface tissue from the electric field component is minimized.

23. The method of claim 22 further comprising the step of positioning the open ends of said plurality of microwave waveguide applicators continuous, whereby the resultant field produced by said applicators is substantially continuous.