Noninvasive device for photoelectrically measuring the property of arterial blood

• US 4,586,513 A
• Filed: 02/17/1983
• Issued: 05/06/1986
• Est. Priority Date: 02/19/1982
• Status: Expired due to Fees

• Current Assignee: Minolta Camera Kabushiki Kaisha
• Original Assignee: Minolta Camera Kabushiki Kaisha
• Inventors: Hamaguri, Kenji
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Hanley, John C.
• Application Number:
  US06/467,431
• Time in Patent Office: 1,174 Days
• Field of Search: 128/633, 128/634, 128/666, 128/665, 356/41
• US Class Current: 600/326
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: G01J 1/1626 Arrangements with two photodetectors, the signals of which are compared
• CPC Class Codes: G01J 2001/161 Ratio method, i.e. Im/Ir
• CPC Class Codes: G01N 21/314 with comparison of measurements at specific and non-specific wavelengths dual wavelength spectrometry G01J3/427
• CPC Class Codes: G01N 2201/1245 Averaging several measurements

Abstract

A noninvasive device for photoelectrically measuring a property of arterial blood is provided. Light that contacts living tissue with arterial blood is converted into a pair of electrical signals. The electrical signals are processed to provide information of the amplitude of the measured signals and are further processed to produce a final output signal that is substantially a square function of a ratio between the electrical signals representative of the amplitudes.

Claims

1. A noninvasive device for photoelectrically measuring a property of arterial blood in living tissue comprising:

means for providing a source light to enter into living tissue, the light means remains outside the living tissue and only the light passes into the living tissue;

means for photoelectrically measuring the intensity of the source light emerging from the living tissue after contact with the arterial blood therein, at a pair of separate wavelengths, and for producing a pair of electric signals, respectively, each signal including an alternating-current component and a direct-current component;

means for calculating information from the signals representative of the relative amplitude of the alternating-current component compared to the direct-current component for each of the measured wavelengths and for producing first and second calculated outputs, respectively representing the relative amplitudes at each wavelength;

means for obtaining a final output signal that is a linear function of the square of a ratio between the first and second calculated outputs; and

means for indicating the property of the arterial blood in response to the final output.

2. The invention of claim 1, wherein said obtaining means includes means for approximating the linear function of the square of the ratio as a joint combination of a plurality of linear functions of the ratio.

3. The invention of claim 2, wherein said approximating means includes means for selecting one of the plurality of linear functions for use in approximating, the one selected being dependent upon the level of the ratio.

4. The invention of claim 1, wherein the calculating means includes a pair of means, responsive to the pair of electric signals of the photoelectrically measuring means, for producing the first and second calculated outputs, respectively.

5. The invention of claim 1, wherein the pair of wavelengths consist of a first wavelength at which the light absorption coefficient of the hemoglobin and that or the hemoglobin oxide are equal to each other, and a second wavelength at which the two light absorption coefficients are different from each other, and wherein the final output signal is representative of the oxygen saturation.

6. The invention of claim 1, wherein the pair of wavelengths consists of a first wavelength at which light absorption by a pigment to be measured in the blood does not occur, and a second wavelength at which absorption by the pigment effectively occurs relative to the first wavelength, and wherein the final output signal is representative of the density of the pigment.

7. The invention of claim 1, wherein the obtaining means includes a microprocessor and an associated digital memory circuit.

8. The invention of claim 1, wherein the obtaining means includes means for previously storing various values for the final output signal in relation to a variety of possible combinations of values for the first and second calculated outputs, and means for searching a specific value for the final output signal in accordance with a specific combination of values for the first and second calculated outputs actually obtained by the calculating means.

9. A noninvasive device for photoelectrically measuring a property of arterial blood in living tissue comprising:

means for providing a source light to enter into living tissue from the outside thereof;

means for photoelectrically measuring the intensity of the source light emerging from the living tissue after contact with the arterial blood contained therein, at a predetermined pair of wavelengths within the source light and for producing a pair of electric signals, respectively representing the intensity at each wavelength;

means for presenting information representative of the relative amplitude of each of the electric signa with respect to a reference level;

means for obtaining a final output signal that is a linear function of the square of a ratio between the information from said presenting means for the first of the pair of wavelengths and that for the second thereof; and

means for indicating the property of the arterial blood in response to the final output signal.

10. A noninvasive device for photoelectrically measuring the oxygen saturation of arterial blood in living tissue having hemoglobin and hemoglobin oxide comprising:

means for providing a source light to enter into living tissue, the light means remains outside the living tissue and only the light passes into the living tissue;

means for photoelectrically measuring the intensity of the source light emerging from the living tissue after contact with the arterial blood therein, at a pair of separate wavelengths, and for producing a pair of electric signals, respectively, each signal includes an alternating-current component and a direct-current component, wherein the pair of wavelengths consists of a first wavelength at which the light absorption coefficient of the hemoglobin and that of the hemoglobin oxide are equal to each other, and a second wavelength at which the two light absorption coefficients are different from each other;

means for determining the amplitude of the alternating-current component of each of the signals, respectively and for producing first and second outputs, respectively representing the relative amplitudes of the alternating current component of each signal with respect to the D.C. component;

means for obtaining a final output signal that is a linear function of the square of a ratio between the first and second outputs including a microprocessor and a digital memory circuit, the digital memory circuit having stored therein various values for the final output signal in relation to a variety of possible respective combinations of values for the first and second outputs, the microprocessor searching a specific value for the final output signal in accordance with a predetermined combination of values for the first and second outputs actually obtained by the determining means; and

means for indicating the oxygen saturation of the arterial blood in response to the final output signal value selected.