Drug administration device

• US 4,692,147 A
• Filed: 07/19/1985
• Issued: 09/08/1987
• Est. Priority Date: 04/02/1980
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Duggan, Stephen R.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/757,092
• Time in Patent Office: 781 Days
• Field of Search: 604/31, 604/50, 604/65, 604/66, 604/67, 604/70, 604/93, 604/890, 604/164, 604/891, 128/DIG. 12, 128/DIG. 13, 128/419 PG, 128/419 PT
• US Class Current: 604/891.1
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/353 using mechanical means, e.g. subcutaneous pushbuttons
• CPC Class Codes: A61M 5/14232 Roller pumps
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

An implantable drug administration device can be non-invasively programmed to change both the dosage amount and the dosage interval. Verification of received dosage and interval commands is being achieved by means of an audio transducer which is attached to the device case. Application of a magnet or a programmer to the device inhibits drug delivery.

Claims

1. A medical device comprising:

reservoir for the storage of liquid;

means operatively coupled to said reservoir for dispensing said liquid;

means operatively coupled to said dispensing means for controlling said dispensing means in response to programming signals; and

means for generating programming signals wherein said programming signals further comprise a set of dispensing signals wherein each of said dispensing signals further comprises a dosage value and an interval value representing a time period wherein no liquid is dispensed.

2. A medical device according to claim 1 wherein said controlling means further comprises a microprocessor having memory means for storing each of said set of dispensing signals and timing means for sequentially causing said dispensing means to dispense from said reservoir an amount of said liquid corresponding to said dosage value after the elapse of said interval value for each of said dispensing signals within said set of dispensing signals.

3. A medical device according to claim 2 wherein said generating means causes an interrupt to said microprocessor upon generation of said programming signals.

4. An implantable medical device comprising:

reservoir for the storage of a liquid;

means operatively coupled to said reservoir for dispensing said liquid;

means for receiving external programming signals comprising updated dosage information and internal command information signals;

means operatively coupled to said dispensing means for controlling said dispensing means in response to said external programming signals; and

means operatively coupled to said controlling means for inhibiting said dispensing means while receiving said external programming signals.

5. An implantable medical device according to claim 4 further comprising:

means operatively coupled to said controlling means for reinitiating said dispensing means upon completion of said external programming signals.

6. An implantable medical device comprising:

reservoir for the storage of a liquid;

means operatively coupled to said reservoir for dispensing said liquid;

means for receiving external programming commands;

means responsively coupled to said receiving means for storing said external programming commands;

means operatively coupled to said dispensing means for controlling said dispensing means in response to said stored external programming commands; and

means for notifying an operator of said external programming commands stored in said storing means.

7. An implantable medical device according to claim 6 further comprising:

means for powering either said dispensing means or said notifying means.

8. A drug dispenser system comprising:

external programmer means for generating and transmitting programming signals, said programming signals comprising time interval data, dosage data and metering control data and means for individually generating and transmitting said programming signals;

an implantable drug dispenser which includes;

reservoir means for storage of a liquid drug;

delivery means for delivering said liquid drug to the human body;

metering means, coupled between said reservoir means and said delivery means for controlling the flow of drug from said reservoir means to said human body;

receiver means for receiving said time interval data, dosage data and metering control data, said receiver means further comprising first storage means for storing said time interval data, second storage means for storing said dosage data, and third storage means for storing said metering control data, said third storage means having a plurality of individually addressable storage locations, said dosage data indicative of one of said plurality of said individually addressable storage locations of said third storage means;

timer means responsive to said dosage interval data stored in said first storage means for timing out a dosage interval and for initiating a dosage interval time out signal at the expiration of said dosage interval; and

control means responsive to said timing means for causing said metering means to deliver a predetermined quantity of said liquid drug in response to said dosage interval time out signal, said control means comprising addressing means coupled to said second storage means and said third storage means for addressing said third storage means at said one of said plurality of storage locations of said third storage means indicated by said dosage data in said second storage means and metering control means for controlling operation of said metering means according to said metering control data in said addressed one of said plurality of storage locations in said third storage means.

9. A system according to claim 8 wherein said metering means comprises a roller pump coupled thereto a stepper motor coupled thereto wherein said pump is driven by said stepper motor, and wherein said metering control data specifies a predetermined operational sequence for said stepper motor.

10. A system according to claim 9 wherein said metering control comprises means for generating a predetermined number of electrical pulses in combination with said stepper motor wherein said pulses are applied to said stepper motor, and wherein said metering control means applies said predetermined number of electrical pulses to said stepper motor.

11. A system according to claim 10 wherein said metering control data further comprises data indicative of pulse widths of and pulse intervals between said predetermined number of electrical pulses to be applied to said stepper motor, wherein said receiver means further comprises fourth storage means for storing said metering data related to pulse intervals and pulse widths, and wherein said metering control means applies said predetermined number of electrical pulses to said stepper motor in accordance with said metering control data stored in said fourth storage means.