Dialysis system and method
First Claim
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1. An apparatus for equilibrating dialyzable components from a complex fluid for analysis or for adding specified components to a fluid, comprising:
- (1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane;
(2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and
(3) fluid communication means adapted to pass a membrane solution to and from said body portion wherein said fluid communication means comprises a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other.
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Abstract
An apparatus and a method of use for removing specified dialyzable components from a complex reference fluid such as, for example, blood. The invention includes a semi-permeable tubular dialysis membrane, which is inserted into the reference fluid. An equilibration fluid is injected into the tubular membrane and allowed to equilibrate with the outside reference fluid. The equilibrated fluid is then removed for analysis.
201 Citations
10 Claims
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1. An apparatus for equilibrating dialyzable components from a complex fluid for analysis or for adding specified components to a fluid, comprising:
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(1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane; (2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and (3) fluid communication means adapted to pass a membrane solution to and from said body portion wherein said fluid communication means comprises a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A dialysis system having a size and shape to fit within a blood vessel for equilibrating dialyzable components in a blood stream, said system comprising:
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(1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane, wherein said body portion is substantially of uniform cross-section and the permeability of said body portion extends along the length of said tubular membrane between its proximal and distal ends; (2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and (3) fluid communication means adapted to pass a membrane solution and from said body portion, said fluid communication means comprising a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other.
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10. A method for equilibrating dialyzable components in a complex fluid for analysis comprising:
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(1) placing a dialysis apparatus into said fluid, said apparatus comprising a body portion including a flexible elongated tubular dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzing membrane, a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion, an elongated tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first end and a second end wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portions and said conduit communicate directly with each other, and said conduit being adapted to receive a means for injecting and withdrawing a membrane solution into said body portion lumen in such a manner that the distal portion of said injecting means is in adjacent and direct communication with said body portion lumen; (2) injecting a membrane solution through said conduit into said lumen of said tubular membrane, said membrane solution being adapted to equilibrate with said complex fluid, (3) maintaining said membrane solution in said lumen of said tubular membrane for a time sufficient to equilibrate said membrane solution; and (4) withdrawing said equilibrated membrane solution from said lumens for analysis.
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Specification