Cardiac pacer and method providing means for periodically determining capture threshold and adjusting pulse output level accordingly

• US 4,729,376 A
• Filed: 05/28/1985
• Issued: 03/08/1988
• Est. Priority Date: 05/28/1985
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: DeCote, Robert Jr.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/738,606
• Time in Patent Office: 1,015 Days
• Field of Search: 128/419 P, 128/419 PG, 128/419 PT
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

A low-power cardiac pacer and method includes an automatic capture threshold determination system wherein the minimum pulse energy required to reliably stimulate contractions of a patient'"'"'s heart is periodically determined. The energy level of pacing pulses generated by the pacer is automatically set in accordance with the determined capture threshold level to reduce battery current drain and thereby extend the pacer'"'"'s useful life.

Claims

1. A cardiac pacer for stimulating contractions in a patient heart having a recurring refractory period of predetermined minimum duration, comprising:

means for establishing a pacing period within the refractory period of the heart;

pacing pulse generating means for generating a series of pacing signals for application to the heart, said generating means having a first operating mode wherein each of said pacing signals comprises a single pulse occurring during said refractory period, and a second operating mode wherein each of said signals comprises a pair of pulses occuring during said pacing period, the energy level of said pulses in said first operating mode being dependent on an applied amplitude control signal;

means defining recurring test periods;

pacer control means for conditioning said pacing pulse generating means to said second operating mode during each of said test periods;

capture thereshold detection means responsive to contractions within the heart induced by paired pulses from said generating means during said second mode of operation thereof, periodically operable during each of said recurring test periods for automatically determining the minimum pacing pulse energy required during each of said test periods to reliably stimulate contractions in the patient heart; and

amplitude control means responsive to said capture threshold detection means for providing following each of said test periods an amplitude control signal to said pacing pulse generating means to cause said generating means to thereafter generate pacing pulses having an energy level related to said capture threshold.

2. A cardiac pacer as defined in claim 1 wherein said amplitude control signal developed by said amplitude control means exceeds said threshold level by a predetermined margin factor whereby the energy level of said pacing pulses set by said amplitude control means exceeds said capture threshold by said margin factor.

6. A cardiac pacer as defined in claims 1 or 5 wherein said closely spaced pulses are generated with equal amplitudes, and said capture thereshold detection means compare said generated closely-spaced pacing pulses with the electrical response of the heart thereto during said test period to detect capture at the energy level of said pulses.

7. A cardiac pacer as defined in claim 6 wherein capture threshold determination means vary energy level of said generated closely spaced pulses within a range extending above and below said capture threshold.

3. A cardiac pacer for stimulating contractions in a patient heart having a recurring refractory period of predetermined minimum duration, comprising:

pacing pulse generating means for generating recurring pacing signals for application to the heart, said pacing means having a first operating mode wherein each signal comprises a single pulse, and a second operating mode wherein each signal comprises a pair of closely spaced pulses;

means defining recurring test periods;

pacer control means for conditioning said pacing pulse generating means to said second operating mode during said recurring test periods;

capture threshold detection means responsive to contractions of the heart in response to said closely spaced pulses during each of said test periods for determining the capture threshold of the heart; and

amplitude control means for causing said generating means to generate pacing pulses at an energy level related to said determined capture threshold during said first mode of operation.

4. A caridac pacer as defined in claim 3 wherein said amplitude control signal developed by said amplitude control means exceeds said threshold level by a predetermined margin factor whereby the energy level of said pacing pulses set by said amplitude control means exceeds said capture threshold by said margin factor.

5. A cardiac pacer as defined in claim 3 wherein said pacer includes means for establishing a pacing period within the refractor period of the heart, and said closely spaced pair of pulses generated by said generating means occur during said pacing period.

8. A power-conservative method of pacing a patient heart comprising the steps of:

defining first and second operating modes;

generating recurring pacing signals for application to the heart wherein, said pacing signals each comprising a single pacing pulse in said first mode of operation, and a pair of closely spaced pulses in said second mode of operation;

periodically analyzing contractions to the heart resulting from the closely spaced double pacing pulses in said second mode to determine the capture threshold of the heart; and

maintaining the amplitude of said pacing pulses at an amplitude related to said capture threshold during said first mode of operation.

9. A method of pacing as defined in claim 8 comprising the additional step of maintaining the amplitude of said pacing pulses above that of said capture threshold by a predetermined margin factor.

10. A method of pacing as defined in claim 8 including the additional step of establishing a pacing period within the refractory period of the heart, and wherein said generating of recurring pacing signals comprises generating said closely spaced pulses during said pacing period.

11. A method of pacing as defined in claim 10 wherein said generating means generate said closely spaced pulses at equal amplitudes, and including the additional step of comparing said generated closely spaced pulses with the electrical response of the heart thereto to detect capture at the energy level of said pulses.

12. A method of pacing as defined in claim 11 includes the additional step of varying the energy level of said generated closely spaced pulses within a range extending above and below said threshold level.