Diagnostic methods and apparatus employing monitoring of myocardial ischemia
First Claim
1. A method for monitoring the onset of a myocardial ischemic event during the induction of anesthesia in a subject comprising the steps ofmonitoring values of a parameter corresponding to systemic vascular resistance of the subject, anddetecting the onset of myocardial ischemic events during the induction of anesthesia when said monitored parameter value changes in accordance with a selected numerical amount.
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Abstract
A method and apparatus monitor myocardial ischemic events in various medical applications for providing continuous and contemporaneous information regarding, for example, modifying the amount of medication for a patient, determining response during (PTCA) balloon angioplasty, monitoring the onset of myocardial ischemic events during induction of anesthesia, determining painless myocardial ischemia in a resting patient, and monitoring the onset of myocardial ischemic during stress conditions in a patient. The method and apparatus also provide a calibration method for determining from a Resistive Index and using the resulting transformation for calculating, on a continuing basis, both systemic vascular resistance and cardiac output.
101 Citations
13 Claims
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1. A method for monitoring the onset of a myocardial ischemic event during the induction of anesthesia in a subject comprising the steps of
monitoring values of a parameter corresponding to systemic vascular resistance of the subject, and detecting the onset of myocardial ischemic events during the induction of anesthesia when said monitored parameter value changes in accordance with a selected numerical amount.
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3. A method for quantifying the extent of myocardial ischemic response during (PTCA) balloon angioplasty of a subject comprising the steps of
monitoring values of a parameter corresponding to systemic vascular resistance of the subject, and detecting when said parameter value changes by a selected numerical value for indicating the degree of myocardial ischemia developed during said (PTCA) balloon angioplasty.
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5. A method for monitoring the onset of painless myocardial ischemia in a resting patient comprising the steps of
monitoring a parameter corresponding to systemic vascular resistance of the patient, and detecting when the parameter being monitored changes above or below a predetermined base line value as an indication that a myocardial ischemic change in the patient has occurred.
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7. A method for monitoring the onset of myocardial ischemia during a stress condition in a patient comprising the steps of
monitoring a parameter value corresponding to the systemic vascular resistance of the subject, and detecting when said parameter value increases a selected amount of determining the onset of the myocardial ischemic event during said stress condition.
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9. A method for determining the drug dose level for inhibiting myocardial ischemic events in a subject comprising the steps of:
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monitoring a parameter value corresponding to the systemic vascular resistance of the subject, recognizing the time of myocardial ischemic event by a selected increase in value of said monitored parameter, and increasing the subject drug level in response to said selected increase in the monitored parameter value. - View Dependent Claims (10)
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11. A method for continuously determining systemic vascular resistance and cardiac output of a patient comprising the steps of
A. generating values of a parameter corresponding to systemic vascular resistance of the patient by a first method; -
B. determining the systemic vascular resistance of the patient at two operating conditions using a method other than that of step A above; and C. calibrating said determining method of step A for providing a one-to-one reading of the thus calibrated parameter and said systemic vascular resistance. - View Dependent Claims (12, 13)
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Specification