Method for determining respiratory function

• US 4,802,492 A
• Filed: 03/11/1987
• Issued: 02/07/1989
• Est. Priority Date: 03/11/1987
• Status: Expired due to Fees

• Current Assignee: National Jewish Center for Immunology and Respiratory Medicine
• Original Assignee: National Jewish Center for Immunology and Respiratory Medicine
• Inventors: Grunstein, Michael M.
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US07/024,684
• Time in Patent Office: 699 Days
• Field of Search: 128/720, 128/716, 128/725
• US Class Current: 600/533
• CPC Class Codes: A61B 5/085 Measuring impedance of respiratory organs or lung elasticity

Abstract

A method for determining respiratory function in subjects, as well as the apparatus thus employed. The method involves blocking exhalation while the subject inhales spontaneously. Increased volume in the lungs and face mask pressure are measured to determine respiratory compliance. When the exhalation block or occlusion is removed, flow of exhaled air and volume changes in the lungs are measured to determine the time constant. The relationship between time constant and respiratory compliance permits determination of respiratory resistance.

Claims

1. A method for measuring respiratory function in a subject comprising:

(a) covering nose and mouth of said subject with a sealable face mask, said face mask equipped with means connected to a flowmeter, a two way valve with a first port delivering air for inhalation and a second port for removing exhaled air, and connecting means connecting said face mask to a pressure transducer;

(b) permitting spontaneous breathing by said subject through said first port for a predetermined number of breaths while occluding exhalation of air inhaled by said patient through said first port;

(c) measuring progressive cumulation of inspired volume in the lungs of said subject with said flowmeter and increases in mask pressure with said pressure transducer;

(d) relating said volume cumulation measured with said flowmeter and mask pressure increases measured with said pressure transducer to determine the subject'"'"'s respiratory compliance;

(e) spontaneously releasing said exhalation occlusion;

(f) measuring flow of exhaled air through said second port following release of said occlusion with said flowmeter;

(g) measuring volume change in said subject'"'"'s lungs following release of said occlusion;

(h) relating said measured flow and said volume change to determine the time constant of said subject'"'"'s respiratory system; and

,

(i) relating the time constant and said respiratory compliance to determine respiratory system resistance in said subject.

2. A method as in claim 1, wherein said subject is an infant.

3. A method as in claim 1, wherein said subject is infirm.

4. A method as in claim 1 wherein said said respiratory system resistance determination is an indication of presence or lack thereof of a respiratory abnormality.

5. A method as in claim 4, wherein said abnormality is a respiratory abnormality characterized by airflow resistance abnormality.

6. A method as in claim 5, wherein said abnormality is asthma.

7. A method as in claim 5, wherein said abnormality is a chronic obstructive pulmonary disease.

8. A method as in claim 4, wherein said abnormality is characterized by parenchymal lung stiffness.

9. A method as in claim 8, wherein said abnormality is emphysema.

10. A method as in claim 8, wherein said abnormality is a restructive lung disease.