Insulin delivery method and apparatus

• US 4,822,337 A
• Filed: 06/22/1987
• Issued: 04/18/1989
• Est. Priority Date: 06/22/1987
• Status: Expired due to Term

• Current Assignee: Martin, Roy, Robert Lerner, Stanley Newhouse
• Original Assignee: Martin, Roy, Robert Lerner, Stanley Newhouse
• Inventors: Lerner, Robert, Martin, Roy, Newhouse, Stanley
• Primary Examiner(s): Yasko, John D.
• Application Number:
  US07/064,355
• Time in Patent Office: 666 Days
• Field of Search: 604/50, 604/51, 604/52, 604/65, 604/66, 604/67
• US Class Current: 604/503
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A method and apparatus for providing for the insulin needs of a diabetic individual utilizes blood flow in the digestive tract as the operative variable. Such blood flow is monitored and when deviations from a base level are sensed insulin is provided in measured amounts. The blood flow may be monitored on a continuous basis to provide real-time analysis and delivery. The system may be under microprocessor control, and may include recording means to allow a record of blood flow and insulin delivery to be made either for insulin need computation or for later review.

Claims

1. A method for providing for the insulin needs of a diabetic individual, comprising:

mounting a blood flow sensor on the individual such that digestive tract blood flow may be monitored;

monitoring said digestive tract blood flow and forming an electrical data signal relating thereto;

computing the individual insulin needs based upon said electrical data signal; and

delivering an amount of insulin responsive to said determined need to the individual.

2. The method of claim 1 wherein said step of monitoring blood flow comprises monitoring blood flow in the portal vein.

3. The method of claim 2 wherein said step of monitoring blood flow comprises the step of inserting a catheter containing monitoring means proximate said portal vein through the obliterated umbilical vein.

4. The method of claim 1 wherein said processing step comprises comparing sensed blood flow rate to a predetermined level and said delivery step comprises delivering insulin at a pre-established rate until said blood flow rate returns to said pre-determined level.

5. A method for providing of the insulin needs of an individual, comprising:

mounting a blood flow sensor on the individual such that digestive tract blood flow may be monitored;

monitoring said digestive tract blood flow and forming a data signal embodying such blood flow data at a first time;

computing the individual'"'"'s insulin needs based upon said blood flow data;

delivering an amount of insulin responsive to said computed insulin need;

storing said blood flow and insulin amount in memory means;

sampling said digestive tract blood flow at a second time;

recalculating said individual'"'"'s insulin needs based upon said second time blood flow data and said stored blood flow and insulin amount data; and

storing said recalculated insulin amount and second time blood flow data in system memory.

6. Apparatus for administering insulin to a patient in accordance with the patient'"'"'s requirements, comprising a blood flow sensor located upon the patient to sense digestive tract blood flow;

control means operatively connected to said flow sensor to calculate the insulin need of the patient based upon data received from said flow sensor; and

insulin dispensing means operatively connected to said control means to administer the amount of insulin calculated by said control means.

7. The apparatus of claim 6 wherein said blood flow sensor comprises ultrasonic transducer means.

8. The apparatus of claim 7 wherein said ultrasonic transducer means comprises a catheter positioned to monitor blood flow in the digestive system.

9. The apparatus of claim 8 wherein said catheter is located approximate the portal vein.

10. The apparatus of claim 9 wherein said catheter is located within the obliterated umbilical vein.

11. The apparatus of claim 10 wherein said control means comprises a microprocessor.

12. The apparatus of claim 11 wherein said control means includes means for periodic storage of blood flow data received from said blood flow sensor and administered insulin data.

13. The apparatus of claim 12 wherein said control

means calculates the insulin need of the patient based upon the data received from said flow sensor and said stored blood flow and administered insulin data.

14. The apparatus of claim 11 wherein said control means is mounted in a pouch worn by the user.

15. The apparatus of claim 13 wherein said control means is operatively connected to said blood flow sensor by electrical signal transmission means located at least partially within the obliterated umbilical vein.

16. The apparatus of claim 11 when said control means is battery powered.