Control of blood flow

• US 4,828,544 A
• Filed: 05/01/1986
• Issued: 05/09/1989
• Est. Priority Date: 09/05/1984
• Status: Expired due to Fees

• Current Assignee: Quotidian No 100 Pty Limited
• Original Assignee: Quotidian No 100 Pty Limited
• Inventors: Pace, Gary W., Taylor, George R., Lane, Rodney J.
• Primary Examiner(s): Pellegrino, Stephen C.
• Assistant Examiner(s): Lewis, Ralph
• Application Number:
  US06/864,699
• Time in Patent Office: 1,104 Days
• Field of Search: 604/8-10, 604/99, 604/256, 128/79, 128/1 R, 128/325, 128/326, 128/346, 128/344, 128/686, 128/DIG. 25, 128/899, 251/341, 251/342, 251/348, 600/29-31, 623/1
• US Class Current: 604/9
• CPC Class Codes: A61B 17/12 for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord specially adapted for vas deferens or fallopian tubes A61F6/20; materials for ligaturing blood vessels A61L17/00
• CPC Class Codes: A61F 2/26 Penis implants
• CPC Class Codes: Y10S 128/25 Artificial sphincters and devices for controlling urinary incontinence

Abstract

A blood flow control system comprising a primary arteriovenous fistula connecting a blood source to a vein, and a secondary fistula connected to the first fistual leading to a venous sink. A blood flow control device is engaged with the primary fistula so as to impede the flow therethrough, and is disposed between the secondary fistula and the vein, and it is actuated transcutaneously, whereby restriction of the blood flow through the primary fistula increases the flow of blood to the venous sink.

Claims

1. A blood flow control system comprising a primary arteriovenous fistula fluidly connecting a blood source to a vein, a secondary fistula fluidly connected to said primary fistula leading to a venous sink;

and blood flow control means engaged with the primary fistula so as to impede the flow therethrough, and disposed between the secondary fistula and the vein and being actuated transcutaneously;

whereby restriction of the blood flow through the primary fistula by the blood flow control means increases the flow of blood to the venous sink.

2. A blood flow control system according to claim 1, wherein the blood flow control means includes pressure means capable of engaging and constricting the primary fistula, pump means in fluid communication with the pressure means adapted to inflate the pressure means so as to restrict the flow of blood from the primary fistula to the vein and means for deflating the pressure means.

3. A blood flow control system according to claim 2 wherein the pump means includes a balloon connected through a valve to said pressure means.

4. A blood flow control system according to claim 3 wherein the valve is adapted to provide controlled back-flow so that the blood flow restriction of the primary fistula decreases over a pre-determined period.

5. A blood flow control system according to claim 3 wherein the valve includes a valve seat and a flexible diaphragm within a valve body and wherein the valve is opened by deforming the valve body.

6. A blood flow control system according to claim 3 wherein the valve is normally closed and can be opened by the application of a compressive force on the exterior of the valve, said valve comprising:

(i) a valve body defining a valve chamber,

(ii) an inlet to and an outlet from the chamber,

(iii) a valve seat member disposed across the valve chamber and having a bore in communication with the inlet and selectively in communication with the outlet,

(iv) a perforated support member positioned in the valve chamber between the outlet and the valve seat member and having a valve plunger extending therefrom adapted to engage and close the bore of the valve seat member, the arrangement being such that when the valve body is distorted by the application of an external compressive force between the perforated support member and the valve seat member, the valve seat moves away from the plunger towards the inlet whereby the outlet is placed in communication with the inlet.

7. A blood flow control system according to claim 6 wherein the valve seat member is perforated so to provide controlled flow of fluid back to the valve body.

8. A blood flow control system according to claim 3 wherein the valve is normally closed and can be opened by the application of a compressive force on the exterior of the valve, said valve comprising:

(i) a valve body defining a valve chamber,

(ii) an inlet to and an outlet from the chamber,

(iii) a valve seat member having;

(a) an annular body portion held captive within the chamber by the valve body

(b) a bore in communication with the inlet and extending to the outlet,

(c) an annular valve seat around the outlet end of the bore, and

(d) a plunger supported within the bore and extending towards the outlet, and,

(iv) a valve member overlying and normally closing the annular valve seat, said valve member being coupled to the plunger so that when the valve body is distorted by the application of an external compressive force at or adjacent to the inlet, the valve seat member is so distorted that the plunger moves towards the outlet whereby the valve member is moved away from the valve seat so as to place the outlet in communication with the inlet.

9. A blood flow control system according to claim 8 wherein a portion of the valve member is secured to the valve seat and a hinge is formed in the valve member adjacent to the portion secured to the valve seat.

10. A blood flow control system according to claim 1 wherein the blood flow control means comprises magnetic means secured to the primary fistula at a location remote from the epidermis adapted to squeeze the primary fistula under the influence of an exterior magnet.

11. An implantable device for controlling the flow of blood to a vein through a primary arteriovenous fistula and a venous sink through a secondary fistula connected to the primary fistula, comprising inflatable pressure means adapted to engage the primary fistula between the secondary fistula and the vein, pump means in communication with the pressure means adapted to inflate the pressure means, whereby the pressure means restricts the flow of blood through the primary fistula and increases the flow of blood to the venous sink, and means for deflating the pressure means, wherein the means for deflating the pressure means includes a valve that can be opened by the application of a compressive force on the exterior valve, said valve comprising:

(i) a valve body defining a valve chamber

(ii) an inlet to and an outlet from the chamber,

(iii) a valve seat member disposed across the valve chamber and having a bore in communication with the inlet and selectively in communication with the outlet,

(iv) a perforated support member positioned in the valve chamber between the outlet and the valve seat member and having a valve plunger extending therefrom adapted to engage and close the bore of the valve seat member, the arrangement being such that when the valve body is distorted by the application of an external compressive force between the perforated support member and the valve seat member, the valve seat moves away from the plunger towards the inlet whereby the outlet is placed in communication with the inlet.

12. An implantable device for controlling the flow of blood to a vein through a primary arteriovenous fistula and a venous sink through a secondary fistula connected to the primary fistula, comprising inflatable pressure means adapted to engage the primary fistula between the secondary fistula and the vein, pump means in communication with the pressure means adapted to inflate the pressure means, whereby the pressure means restricts the flow of blood through the primary fistula and increases the flow of blood to the venous sink, and means for deflating the pressure means, wherein the means for deflating the pressure means includes a valve that can be opened by the application of a compressive force on the exterior valve, said valve comprising:

(i) a valve body defining a valve chamber

(ii) an inlet to and an outlet from the chamber,

(iii) a valve seat member having;

(a) an annular body portion held captive within the chamber by the valve body

(b) a bore in communication with the inlet and extending to the outlet,

(c) an annular valve seat around the outlet end of the bore, and

(d) a plunger supported within the bore and extending towards the outlet, and

(iv) a valve member overlying and normally closing the annular valve seat, said valve member being coupled to the plunger so that when the valve body is distorted by the application of an external compressive force at or adjacent to the inlet, the valve seat member is so distorted that the plunger moves towards the outlet whereby the valve member is moved away from the valve seat so as to place the outlet in communication with the inlet.

13. A normally closed valve which can be opened by the application of a compressive force on the exterior of the valve, comprising:

(i) a valve body defining a valve chamber,

(ii) an inlet to and an outlet from the chamber,

(iii) a valve seat member having;

(a) an annular body portion held captive within the chamber by the valve body,

(b) a bore in communication with the inlet and extending to the outlet,

(c) an annular valve seat around the outlet end of the bore, and

(d) a plunger supported within the bore and extending towards the outlet, and,

(iv) a valve member overlying and normally closing the annular valve seat, said valve member being coupled to the plunger so that when the valve body is distorted by the application of an external compressive force at or adjacent to the inlet, the valve seat member is so distorted that the plunger moves towards the outlet whereby the valve member is moved away from the valve seat so as to place the outlet in communication with the inlet, wherein a portion of the valve member is secured to the valve seat and a hinge is formed in the valve member adjacent to the portion secured to the valve seat.

14. A blood flow control system, comprising:

a first blood flow path fluidly connecting a blood source to a vessel, a second blood flow path fluidly connecting said first blood flow path to a venous sink, and blood flow control means engaged with said first blood flow path between said second blood flow path and said vessel, said blood flow control means including an inflatable cuff adapted to constrict said first blood flow path thereby to restrict the flow of blood through said first blood flow path an to increase the flow of blood through said second blood flow path, means for inflating the cuff and means for deflating the cuff, said blood flow control means being fully implanted within a body and said inflating and deflating means being operable by pressure applied transcutaneously.

15. The blood flow control system according to claim 14, wherein said first blood flow path is a fistula.

16. The blood flow control system according to claim 14, wherein said second blood flow path is a fistula.

17. The blood flow control system according to claim 14, wherein said first and second blood flow paths are fistulas.