Novel endotracheal tube and mass spectrometer

• US 4,850,371 A
• Filed: 06/13/1988
• Issued: 07/25/1989
• Est. Priority Date: 06/13/1988
• Status: Expired due to Term

• Current Assignee: John H. Broadhurst, Marvin B. Bacaner
• Original Assignee: John H. Broadhurst, Marvin B. Bacaner
• Inventors: Bacaner, Marvin B., Broadhurst, John H.
• Primary Examiner(s): Pearson, Charles
• Assistant Examiner(s): Lewis, Aaron J.
• Application Number:
  US07/205,668
• Time in Patent Office: 407 Days
• Field of Search: 128/207.14, 128/207.15, 128/719, 128/720, 128/725, 128/730, 604/43, 604/45, 604/283, 138/40, 138/44
• US Class Current: 600/532
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61M 16/0459 one cuff behind another
• CPC Class Codes: A61M 16/0493 with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
• CPC Class Codes: A61M 16/0858 Pressure sampling ports
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2230/432 partial CO2 pressure (P-CO2)
• CPC Class Codes: A61M 2230/435 partial O2 pressure (P-O2)

Abstract

A non-invasive apparatus for continuously measuring the cardiac output and cardio-respiratory function includes a gas sampling device which is inserted into the mouth of a human subject. The gas sampling device may be a disposable endotracheal tube or a smaller disposable mouthpiece. Each of these gas sampling devices is provided with a plurality of passages for sampling the lung gases and for continuously sampling the gas pressure on opposite sides of a capillary restriction member. A miniature motor pump mass spectrometer module is mounted on the upper end of the endotracheal tube or mouthpiece. Electronic circuitry connected to the mass spectrometer permits constant visual monitoring of the cardiac output and cardio-respiratory function.

Claims

1. An apparatus for sampling and analyzing the lung gases from a human subject, comprising:

a gas sampling device for insertion into the mouth of a human subject including a double wall tube having upper and lower ends and including inner and outer tube elements, the interior of said inner tube defining a central passage therethrough, means dividing the space between the inner and outer tube elements into a plurality of elongate passages extending throughout the length of the double wall tube, a plurality of openings in the lower end portion of said inner tube element, each opening communicating with one of said passages, a capillary restriction member positioned within said inner tube having a plurality of capillary openings therein for restricting the flow of air through said central passage,

a miniature motor pump mass spectrometer module, including a mass spectrometer, means connecting the mass spectrometer to a vacuum source, means connecting the motor pump mass spectrometer module with the upper end of said gas sampling device for intercommunicating a pair of said passages with said motor pump mass spectrometer module whereby lung gases are directed to said mass spectrometer,

a differential pressure transducer with a pair of said passages whereby the gas pressure located below and above said capillary restriction member are sensed, and

electronic circuitry cooperating with said mass spectrometer and said pressure transducer for analyzing the lung gases and lung capacity of the human subject.

2. The apparatus as defined in claim 1 wherein said gas sampling device comprises an elongate endotracheal tube which extends downwardly into the lower trachea of the human subject.

3. The apparatus as defined in claim 1 wherein said gas sampling device comprises a mouthpiece having a lower end terminating in the oral cavity of the human subject.

4. The apparatus as defined in claim 2 and means dividing the space between the inner and outer tubular elements into an elongate inflation passage, a tracheal sampling passage, and a tracheal return passage,

a tracheal sample opening and a tracheal return opening in said inner tube communicating with said tracheal sample passage and a tracheal return passage, a pair of inflation openings in said outer tube, and

a pair of inflatable balloon members secured to said outer tube element, each of said inflation openings communicating with one of said balloon members to permit inflation and deflation of the latter, said balloon members, when inflated, engaging the inner surface of the trachea of the human subject and cooperating therewith to define an annular tracheal sampling cell, said tracheal sampling opening and said tracheal return opening communicating with the tracheal sampling cell, means for selectively connecting said tracheal sampling and return passages to said mass spectrometer to permit tracheal tissue gases to be analyzed.

5. The apparatus as defined in claim 1 wherein said motor pump mass spectrometer module includes a motor pump unit including a motor pump housing having an outlet communicating with said mass spectrometer, a non-magnetic divider wall dividing the interior of said motor pump housing into a motor chamber and a pump chamber, a pair of revolvable meshing gears in said motor chamber, and a pair of revolvable meshing gears in said pump chamber, each gear in one chamber being coaxially disposed with a gear in the other chamber,

co-acting magnetic elements on the gear in the motor chamber and on the co-axially disposed gear in the pump chamber,

said pair of passages of said gas sampling device being connected in communicating relation with said pump chamber, and

means connecting the motor chamber to a source of air under pressure to drive said motor chamber gears and thereby drive the pump chamber gears for directing sample gas into said mass spectrometer.

6. A disposable gas sampling device for use in obtaining respiratory gases for analysis from the human subject, comprising:

an elongate flexible double wall tube for insertion into the mouth of a human subject, said double wall tube defining a central passage therethrough and having upper and lower ends and including inner and outer tubular elements,

a plurality of axially extending, peripherally arranged auxiliary passages located between the inner and outer tubular elements of the double wall tube, including a gas sample passage, a return passage, and a pair of pressure sensing passages, a plurality of openings in the lower end portion of the inner tubular element, including a gas sample opening, a return opening, and a pair of pressure sensing openings, said gas sample opening communicating with said gas sample passage to permit lung gases to pass in an upward direction, said return opening communicating with said return passage through which lung gases are returned, each of said pressure sensing openings communicating with one of said pressure sensing passages,

a capillary restriction member positioned within the inner tube element adjacent the lower end portion thereof and having a plurality of axially extending capillary passages therein for restricting the flow of gases through the central passage of the double wall tube, one of said pressure sensing openings being located below the capillary restriction member and the other pressure sensing opening being located adjacent but above said capillary restriction member, and

means on the upper end of said double wall tube to permit the upper end of the sampling device to be connected in communicating relation to a differential pressure transducer and to a mass spectrometer, whereby the lung gases can be analyzed and the lung capacity determined.

7. The disposable gas sampling device as defined in claim 6 wherein said double wall tube comprises an elongate endotracheal tube having its lower end portion extending into the lower trachea of the human subject.

8. The disposable gas sampling device as defined in claim 6 wherein the double wall tube comprises a mouthpiece having a lower end portion extending into the oral cavity of the human subject.

9. The disposable gas sampling device as defined in claim 7 and means dividing the space between the inner and outer tubular elements into an elongate inflation passage, a tracheal sampling passage, and a tracheal return passage,

a tracheal sample opening and a tracheal return opening in said inner tube communicating with said tracheal sample passage and a tracheal return passage, a pair of inflation openings in said outer tube, and

a pair of inflatable balloon members secured to said outer tube element, each of said inflation openings communicating with one of said balloon members to permit inflation and deflation of the latter, said balloon members, when inflated, engaging the inner surface of the trachea of the human subject and cooperating therewith to define an annular tracheal sampling cell, said tracheal sampling opening and said tracheal return opening communicating with the tracheal sampling cell, means for selectively connecing said tracheal sampling and return passages to said mass spectrometer to permit tracheal tissue gases to be analyzed.