Exothermic package body having a layer containing a medicinal component

• US 4,963,360 A
• Filed: 10/26/1988
• Issued: 10/16/1990
• Est. Priority Date: 02/12/1988
• Status: Expired due to Term

• Current Assignee: Zars, Inc.
• Original Assignee: Albert Argaud
• Inventors: Argaud, Albert
• Primary Examiner(s): Cashion, Jr., Merrell C.
• Assistant Examiner(s): Horne, Leon R.
• Application Number:
  US07/262,879
• Time in Patent Office: 720 Days
• Field of Search: 424/443, 424/447, 424/448, 424/449
• US Class Current: 424/443
• CPC Class Codes: A61F 2007/0261 medicated
• CPC Class Codes: A61F 7/03 thermophore, i.e. self-heating, e.g. using a chemical reaction
• CPC Class Codes: A61K 9/703 characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches

Abstract

An exothermic package body having a carrier layer comprising a medicinal component, and an exothermic layer which develops heat when exposed to the air to enhance absorption of the medicinal component through the skin, hence improving medicinal effects.

Claims

1. An exothermic medical package body comprising:

a base sheet;

a carrier layer provided on an obverse surface of said base sheet, said carrier layer comprising 4.0-5.0 g of water, 1-2 g of gelatin, 2-4 g of kaoline, 0.1-0.3 g of antiseptic, 0.2-0.4 g of aluminum chloride, 0.1-0.3 g of propylene glycol, and a medicinal component;

an exothermic layer, provided on a reverse surface of said base sheet, which develops heat when brought into contact with air;

a separable cover for covering said carrier layer;

an air-permeable film covering said exothermic layer, said film to be brought into contact with human skin to transmit heat of said exothermic layer to the skin; and

an air-impermeable packing sheet for sealing and packing said exothermic layer covered by said film.

2. An exothermic medical package body according to claim 1, wherein said medicinal component is selected from the group consisting of marine algae essence, scopolamine, nitroglycerin, clonidine, and estradiol.

3. An exothermic medical package body comprising:

a base sheet;

a carrier layer provided on an obverse surface of said base sheet, said carrier layer comprising cloth or fibers impregnated with a medicinal component;

an exothermic layer, provided on a reverse surface of said base sheet, which develops heat when brought into contact with air;

a separable cover for covering said carrier layer;

an air-permeable film covering said exothermic layer, said film to be brought into contact with human skin to transmit heat of said exothermic layer to the skin; and

an air-impermeable packing sheet for sealing and packing said exothermic layer covered by said film.

4. An exothermic medical package body according to claim 3, wherein said medicinal component is selected from the group consisting of marine algae essence, scopolamine, nitroglycerin, clonidine, and estradiol.