Tissue-compatible medical device and method for manufacturing the same
First Claim
1. A tissue compatible medical device for use on or within a human or animal body, comprisinga matrix comprising a polyurethane elastomer having a main chain which includes an effective amount of less than about 50% by weight of an organic silicone polymer having a molecular weight of from about 500 to about 10,000, andan oligodynamic agent embedded in a substantially spatially uniform distribution within said matrix, said oligodynamic agent comprising from about 1 to about 15% by weight of the total weight of said matrix and releasing metal ions when exposed to body fluids.
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Abstract
A medical device which can be introduced into the body tissue of a human or animal comprises a matrix of a polyurethane elastomer with organic silicone polymer units built into the main polymer chain and an oligodynamic agent spatially distributed uniformly within the matrix. The oligodynamic agent releases bacteriocidal or microbicidal metal ions when exposed to body tissues. The method for manufacturing the medical device is characterized by the addition of the oligodynamic agent in a solid or dissolved form prior to the reaction of the educts with isocyanate.
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9 Claims
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1. A tissue compatible medical device for use on or within a human or animal body, comprising
a matrix comprising a polyurethane elastomer having a main chain which includes an effective amount of less than about 50% by weight of an organic silicone polymer having a molecular weight of from about 500 to about 10,000, and an oligodynamic agent embedded in a substantially spatially uniform distribution within said matrix, said oligodynamic agent comprising from about 1 to about 15% by weight of the total weight of said matrix and releasing metal ions when exposed to body fluids.
Specification