Continuous glucose monitoring and a system utilized therefor
First Claim
1. An in situ method of continuously monitoring the glucose level in the body of a patient including the steps of:
- locating a filter member within the interior of a blood vessel for direct contact with blood therein;
directing said blood within the vessel through the filter member for filtering a clear liquid component of the blood then in the vessel from the blood cells and proteins therein, said clear liquid component containing the glucose to be monitored;
continuously passing said clear liquid component along a predetermined path outside the vessel and entirely within the body of the patient so that the clear liquid component does not leave the body of the patient;
detecting an optical property of the clear component as it moves along said predetermined path; and
employing information obtained regarding the detected optical property to determine the glucose level in the blood.
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Accused Products
Abstract
A continuous process for monitoring blood glucose level includes the steps of segregating a clear liquid component of blood from the protein and cells of the blood, wherein the clear liquid component includes the glucose to be monitored; continuously passing the clear liquid in a predetermined path between a light-emitting and a light-detecting device; detecting an optical property of the clear liquid component of the blood and employing the optical property to determine the glucose level in the blood. The invention also relates to the system for carrying out the continuous glucose monitoring process, and to a device for automatically controlling the pressure level in the system as a function of the breathing pattern of a patient in which the system is implanted.
432 Citations
32 Claims
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1. An in situ method of continuously monitoring the glucose level in the body of a patient including the steps of:
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locating a filter member within the interior of a blood vessel for direct contact with blood therein; directing said blood within the vessel through the filter member for filtering a clear liquid component of the blood then in the vessel from the blood cells and proteins therein, said clear liquid component containing the glucose to be monitored; continuously passing said clear liquid component along a predetermined path outside the vessel and entirely within the body of the patient so that the clear liquid component does not leave the body of the patient; detecting an optical property of the clear component as it moves along said predetermined path; and employing information obtained regarding the detected optical property to determine the glucose level in the blood. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A continuous glucose monitoring system for implantation within the body of a patient to be employed by the patient while the patient is mobile, said system including:
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microporous filter means configured for disposition within the interior of a blood vessel of the patient for direct contact with the blood therein for permitting a clear liquid component of the blood then within the vessel to filter through said filter means, said clear liquid component being separated from the blood cells and proteins of said blood and including the glucose to be monitored; conduit means having a passage for receiving a flow of the clear liquid component from the filter means; optical detecting means for detecting an optical property of the clear liquid component of the blood, said optical detecting means being disposed adjacent the passage in the conduit means through which the clear liquid component flows; measuring means for determining the glucose level in the blood based on the detected optical property of the clear liquid component without the clear liquid component having to leave the body of the patient; and regulating means for controlling the flow of liquid through the passage in the conduit means and past the optical detecting means. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. In a method of continuously monitoring glucose level in the body of a patient, the steps of:
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locating a filter member within the interior of a blood vessel for direct contact with blood therein; directing a clear liquid component of the blood through the filter member for separating the clear liquid component from the blood cells and proteins of the blood then within the vessel, said clear liquid component containing the glucose to be monitored and being confined within a path located entirely within the body of the patient; and monitoring the glucose level in the clear liquid component by means located entirely within the body of the patient so that the clear liquid component does not have to leave the body of the patient during the monitoring thereof. - View Dependent Claims (23, 24, 25, 26)
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- 27. In a glucose monitoring system to be implanted within the body of a patient to be employed by the patient while the patient is mobile, a microporous filter means configured for disposition within a blood vessel of the patient for direct contact with blood therein for permitting a clear liquid component of the blood to filter through said filter means, said clear liquid component being separated from the blood cells and proteins of said blood and containing the glucose to be monitored, said microporous filter means for providing the clear liquid component into a path located entirely within the body of the patient outside of the vessel in which the glucose level is to be monitored so that the clear liquid component does not have to leave the body of the patient during the monitoring thereof.
Specification