8-alkoxyquinolonecarboxylic acid and salts thereof

  • US 4,980,470 A
  • Filed: 01/16/1987
  • Issued: 12/25/1990
  • Est. Priority Date: 01/21/1986
  • Status: Expired due to Term
First Claim
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1. 8-Alkoxyquinolonecarboxylic acid derivatives represented by a general formula (I);

  • ##STR27## wherein R indicates a hydrogen atom or lower alkyl group, R1 indicates a lower alkyl group, R2 indicates a hydrogen atom X indicates a halogen atom, and Z indicates a halogen atom, piperazino group, N-methylpiperazino group, 3-methylpiperazino group, 3-hydroxypyrrolidino group, or pyrrolidino group of the following formula, ##STR28## where, n is 0 or 1, R3 indicates a lower alkylgroup, R4 indicates a hydrogen atom, lower alkyl group, hydroxy-substituted lower alkyl group or halogenated lower alkyl group and R5 indicates a hydrogen atom, lower alkyl group, acyl group or alkoxycarbonyl group, the hydrates or the pharmaceutically acceptable acid addition or alklai salts thereof.

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