Manufacturing method for an occult fecal blood test slide

• US 4,983,416 A
• Filed: 01/19/1988
• Issued: 01/08/1991
• Est. Priority Date: 02/04/1985
• Status: Expired due to Term

• Current Assignee: Propper Manufacturing Co. Inc.
• Original Assignee: Propper Manufacturing Co. Inc.
• Inventors: Hunsinger, Peter, Zwarun, Andrew
• Primary Examiner(s): Hill, Jr., Robert J.
• Application Number:
  US07/147,569
• Time in Patent Office: 1,085 Days
• Field of Search: 427/2, 422/56, 422/57, 422/58, 436/66
• US Class Current: 427/2.13
• CPC Class Codes: G01N 33/526 the element being adapted for a specific analyte
• CPC Class Codes: G01N 33/726 Devices

Abstract

A test slide for conducting a test of occult blood in feces is fabricated with a sheet of filter paper or other reagent carrier material impregnated with a test reagent and packaged in an envelope enclosure which overlies both sides of the reagent carrier sheet. One or more specimen apertures are provided in the enclosure on one side of the reagent carrier sheet to permit the placement of feces specimens on the reagent carrier sheet through the apertures. On the other side, the enclosure is openable to form a test opening (which encompasses the feces specimens) so that a developing reagent can be applied to the other side of the reagent carrier sheet at the location of the specimens. A barrier material, impervious to the passage of liquids, is deposited on the reagent carrier sheet in a line which runs across the area of the test opening. This line of barrier material isolates a portion of the reagent carrier sheet from the specimen areas, preventing the migration of liquids from the specimen area to the isolated area. A line of positive test material is desposited on the reagent carrier sheet in the isolated area to function as a positive test of the operability of the test slide. The barrier prevents contamination of the specimens by the positive test material. In the fabrication of a test slide of this type, the line of barrier material and the line of positive test material are preferably deposited in a single pass of the reagent carrier material from roll stock.

Claims

1. A method for fabricating a test slide including an enclosure comprising the steps of:

a. impregnating a length of carrier material with a reagent which, when mixed with an appropriate developing reagent, provides a color change in the presence of blood;

b. feeding said length of carrier material adjacent a first application station and applying a line of barrier material to one surface of said length of carrier along a first selected line at said first application station;

c. feeding said length of carrier material adjacent a second application station and applying a line of positive test material to said one surface of said length of carrier along a second selected line at said second application station;

d. positioning a sheet of said length of carrier material having said line of barrier material and said line of positive test material on only one side thereof within an enclosure of the test slide.

2. A method in accordance with claim 1 wherein said length of carrier material is fed from a roll and said line of barrier material and said line of positive test material are applied in a single pass of said carrier material.

3. A method in accordance with claim 1 wherein said barrier material is a wax.

4. A method in accordance with claim 3 wherein said line of wax barrier material is deposited from a container of wax maintained at a desired temperature.

5. A method in accordance with claim 1 wherein said line of barrier material and said line of positive test material are applied by printing.

6. A method for fabricating a test slide for identifying the presence of blood in feces comprising the steps of:

a. impregnating a length of carrier material with a reagent which, when mixed with an appropriate developing reagent, provides a color change in the presence of blood;

b. feeding said length of carrier material adjacent a first application station and applying a line of barrier material to one side of said length of carrier along a first selected line at said first application station;

c. feeding said length of carrier material adjacent a second application station and applying a line of positive test material to said one side of said length of carrier along a second selected line at said second application station;

d. positioning a sheet of said length of carrier material having said line of barrier material and said line of positive test material on only one side thereof in an enclosure which overlays both side of said carrier sheet, said enclosure on a given side of said carrier sheet having one or more specimen apertures defining one or more specimen areas and permitting the deposit of feces samples on said carrier sheet through said one or more specimen apertures and said enclosure being openable on the other side of said carrier sheet to provide a test opening encompassing said specimen areas for permitting the deposit of developing reagent on said other side of said carrier sheet at said specimen area; and

e. securing said reagent carrier sheet in said enclosure with said line of barrier material lying across said test opening so as to isolate a section of said carrier sheet within said test opening from said one or more specimen areas with said line of positive test material being in said isolated section.

7. A method in accordance with claim 6 wherein said other side of said carrier is said one side of said carrier.

8. A method in accordance with claim 6 wherein said line of barrier material and said line of positive test material are applied by printing.